Predictive Factors for Second-Line Therapy in Metastatic Renal Cell Carcinoma: A Retrospective Analysis [0.03%]
转移性肾细胞癌二线治疗的预测因素:一项回顾性分析
Hendrik Eggers,Philipp Ivanyi,Mareike Hornig et al.
Hendrik Eggers et al.
Currently, about 50% of patients with metastatic renal cell carcinoma (mRCC) receive a second-line therapy. Therefore, the choice at each subsequent treatment line remains an important issue. In this retrospective study, we sought to identi...
Federico Greco,Eliodoro Faiella,Domiziana Santucci et al.
Federico Greco et al.
Renal medullary carcinoma (RMC) is a rare, highly aggressive tumor recognized as an independent pathological entity. African-descent adolescents and young adults with sickle cell hemoglobinopathy are the most affected groups. This rare subt...
Federico Greco,Lorenzo Sabatino,Francesco Sabatino et al.
Federico Greco et al.
Blepharoptosis is the drooping or inferior displacement of the upper eyelid. Blepharoptosis can be either congenital or acquired. Tumour metastasis is one of the acquired causes of blepharoptosis. The lungs, locoregional lymph nodes, bone a...
Rat Kidney Cancers Determined by Dietary Ochratoxin A in the First Year of Life [0.03%]
幼年黄曲霉素A饮食对大鼠肾脏肿瘤的影响
Peter Mantle
Peter Mantle
An experiment to explore renal carcinogenic efficacy of male rat exposure to dietary ochratoxin A (OTA) only in the first year of life has been made in comparison to lifetime exposure. Ten months exposure to OTA at 300 µg/kg b.w. was suffi...
Multifocal Primary Neoplasms in Kidney Allografts: Evaluation of Two Cases [0.03%]
肾脏移植的多灶性原发肿瘤:两例报告评估
Robert J Ellis,Keng Lim Ng,Hemamali Samaratunga et al.
Robert J Ellis et al.
Renal cell carcinoma (RCC) is the fifth most common malignancy in kidney transplant recipients, with increased risk arising due to immunosuppression. De novo RCC occurrence in kidney allografts is much less common when compared with the nat...
Unusual Case of Coexisting Renal Malignancies: Mucinous Tubular and Spindle Cell Carcinoma Kidney With Sarcomatoid Dedifferentiation [0.03%]
罕见的共存肾恶性肿瘤病例:粘液管状和梭形细胞肾癌伴肉瘤样去分化
Kafil Akhtar,Pragati Agnihotri,Kiran Alam et al.
Kafil Akhtar et al.
Mucinous tubular and spindle cell carcinoma (MTSCC) is a recent entity introduced in the World Health Organization 2004 Classification. It is a tumour of low malignant potential. MTSCC is a subtype of renal cell carcinoma (RCC), which is ch...
Sunny Modi,Kor Woi Tiang,Po Inglis et al.
Sunny Modi et al.
Wilms' tumour (nephroblastoma) is the most common renal tumour in children. Wilms' tumour in adults is extremely rare and has a poorer prognosis than paediatric Wilms' tumour. It is difficult to differentiate adult Wilms' tumour from renal ...
Bradford R Hirsch,John M Burke,Manish Agrawal et al.
Bradford R Hirsch et al.
The treatment of metastatic renal cell carcinoma (mRCC) has changed dramatically in the past decade. As the number of available agents, and related volume of research, has grown, it is increasingly complex to know how to optimally treat pat...
Review of the Interaction Between Body Composition and Clinical Outcomes in Metastatic Renal Cell Cancer Treated With Targeted Therapies [0.03%]
靶向治疗转移性肾细胞癌患者体成分与临床结局相互作用的评述
Steven M Yip,Daniel Y C Heng,Patricia A Tang
Steven M Yip
Treatment of metastatic renal cell cancer (mRCC) currently focuses on inhibition of the vascular endothelial growth factor pathway and the mammalian target of rapamycin (mTOR) pathway. Obesity confers a higher risk of RCC. However, the infl...
Decreased Expression of Inhibitor of Caspase-Activated DNase (ICAD) in Renal Cell Carcinoma - Tissue Microarray of Human Samples [0.03%]
肾细胞癌中半胱天冬酶活化脱氧核糖核酸酶抑制因子(ICAD)表达降低-组织芯片的分析结果
Retnagowri Rajandram,Azad H A Razack,Keng Lim Ng et al.
Retnagowri Rajandram et al.
Although primary localised tumours of renal cell carcinoma (RCC) can be treated relatively successfully with surgery, metastatic RCC has poor prognosis because of late diagnosis and resistance to therapies. In the present study, we were int...