Wilms' Tumor in Adults-Conventional and Unconventional Presentations of a Rare Entity with a Review of Literature [0.03%]
成人肾母细胞瘤——罕见疾病常见及非常见表现结合文献复习
Sujata Tripathi,Amit Mishra,Vijay C Popat et al.
Sujata Tripathi et al.
Wilms' tumor (WT) in adults is a rare neoplasm. Only a few reports are available in the literature. The tumor often masquerades as renal cell carcinoma (RCC). For accurate reporting, histopathological examination (HPE) plays a vital role in...
Partial Nephrectomy, a Comparison between Different Modalities: A Tertiary Care Center Experience [0.03%]
部分肾切除术的不同方式比较：一家三级医疗中心的经验报告
Ahmed Al Asker,Abdulmalik Addar,Mohammed Alghamdi et al.
Ahmed Al Asker et al.
Kidney cancer, with 4% of all malignancies, is one of the most common malignancies occurring among in adults. In Saudi Arabia, kidney cancer comprises 2.3% of all cancers, and its incidence has increased by 33%. Partial nephrectomy (PN) is ...
Nephrectomy Delay of More than 10 Weeks from Diagnosis Is Associated with Decreased Overall Survival in pT3 RCC [0.03%]
肾癌(pT3)的诊断至 nephrectomy 超过10周与总生存率下降相关
Jiping Zeng,Ken Batai,Benjamin R Lee
Jiping Zeng
In this study, we aimed to evaluate the impact of surgical wait time (SWT) on outcomes of patients with renal cell carcinoma (RCC), and to investigate risk factors associated with prolonged SWT. Using the National Cancer Database, we retros...
Dhruv Mahajan,Vishesh Jain,Sandeep Agarwala et al.
Dhruv Mahajan et al.
Renal angiomyolipoma is a rare cause of renal tumor in children. Most are associated with tuberous sclerosis, and the classic type is observed more commonly. Epithelioid angiomyolipoma is even rarer with only limited case reports and series...
Papillary Renal Cell Carcinoma in Lynch/Muir-Torre Syndrome with Germline Pathogenic Variant in MSH6 and Molecular Analysis: Report of a Case and Review of the Literature [0.03%]
Lynch/Muir-Torre综合征伴MSH6胚系致病突变的乳头状肾细胞癌及其分子分析：1例报告及文献复习
Yu Yang,Shweta Dhar,Jennifer Taylor et al.
Yu Yang et al.
Lynch syndrome (LS) is an autosomal dominant inherited disorder due to pathogenic variations in the mismatch repair genes, which predisposes to malignancies, most commonly colon and endometrial carcinoma. Muir-Torre syndrome is a subset of ...
Won Seok W Choi,Julia Boland,Jianqing Lin
Won Seok W Choi
Hypoxia-inducible factor (HIF), an important mediator of hypoxia response, is implicated in tumorigenesis in the setting of pseudohypoxia, such as in the inactivation of von Hippel-Lindau tumor suppressor protein (pVHL), leading to developm...
Thrombotic Microangiopathy Associated with Pazopanib in a Kidney Transplant Recipient [0.03%]
肾脏移植受者的帕唑帕尼相关性血栓性微血管病
Shabana Kalla,Robert J Ellis,Scott B Campbell et al.
Shabana Kalla et al.
Thrombotic microangiopathy (TMA) is characterised by abnormalities in the walls of arterioles and capillaries, precipitated by hereditary or acquired characteristics, and culminating in microvascular thrombosis because of dysregulated compl...
Germline Pathogenic Variants Identified by Targeted Next-Generation Sequencing of Susceptibility Genes in Pheochromocytoma and Paraganglioma [0.03%]
pheochromocytoma和paraganglioma易感基因的靶向高通量测序寻找胚系致病突变
Sinem Yalcintepe,Hakan Gurkan,Fatma Nur Korkmaz et al.
Sinem Yalcintepe et al.
The aim of this study was to evaluate germline variant frequencies of pheochromocytoma and paraganglioma targeted susceptibility genes with next-generation sequencing method. Germline DNA from 75 cases were evaluated with targeted next-gene...
Large Retroperitoneal Paraganglioma Associated with Germline Mutation of the Succinate Dehydrogenase Gene [0.03%]
与SDH基因胚系突变相关的巨大肾周副神经节瘤
Wen Min Chen,Philip Olson,Rohith Arcot et al.
Wen Min Chen et al.
Paragangliomas (PGLs) are rare neural tumors that can be benign or malignant and often associated with familial syndromes. We present a case of a 23-year-old male with a large retroperitoneal PGL found incidentally during the workup of elev...
Bilateral Single-Stage Nephrectomy for Synchronous Bilateral Renal Cell Carcinoma [0.03%]
同步双侧肾细胞癌的单阶段 nephrectomy治疗
Ahmed Kotb,Amer Alaref,David Kisselgoff et al.
Ahmed Kotb et al.
Bilateral synchronous renal cell carcinoma (RCC) is uncommonly encountered. Debate exists among urologists in managing these cases in a single surgery versus staged surgeries. We aim to report our experience in managing encountered cases us...