Treatment Algorithms for Inflammatory Myopathies in Adults: from Guidelines to Clinical Practice [0.03%]
成人炎性肌病治疗方案：从指南到临床实践
Albert Selva-O&#x;Callaghan,Ernesto Trallero-Araguás,Albert Gil-Vila et al.
Albert Selva-O&#x;Callaghan et al.
Purpose of review: Inflammatory myopathies are a heterogeneous group of systemic autoimmune disorders with highly variable clinical presentations. The limited number of clinical trials has hindered the development of stro...
Jennifer M Franks,Michael L Whitfield
Jennifer M Franks
Purpose of review: The emergence of genomic data science stands poised to revolutionize our molecular understanding of the heterogeneity of complex diseases including systemic autoimmune diseases. In systemic sclerosis (S...
Sandra Amara Ogbonnaya-Whittlesey,Dale Kobrin,Maria Casal-Dominguez et al.
Sandra Amara Ogbonnaya-Whittlesey et al.
Purpose of review: Immune-mediated necrotizing myositis (IMNM) is a rare autoimmune disorder characterized by proximal muscle weakness, elevated creatine kinase levels, and necrosis of muscle fibers. While the exact patho...
Soluble Biomarkers for Prediction of Vascular and Gastrointestinal Disease Severity in Patients with Systemic Sclerosis [0.03%]
可溶性生物标志物在系统性硬化症患者血管和胃肠道疾病严重程度预测中的作用
Miruna Carnaru,Monique Hinchcliff
Miruna Carnaru
Purpose of review: Disease severity biomarkers in patients with systemic sclerosis (SSc) provide an early and noninvasive screening tool to identify patients at increased risk for internal organ involvement that may impac...
Personalized Medicine for Systemic Sclerosis-Associated Interstitial Lung Disease [0.03%]
系统性硬化症相关间质性肺病的精准医疗
Angela Ma,Sydney B Montesi
Angela Ma
Purpose of the review: Systemic sclerosis (SSc) is a rare immune-mediated connective tissue disease with high morbidity and mortality. Interstitial lung disease (ILD) is now the leading cause of death for patients with SS...
Utility of Myositis-Specific Autoantibodies for Treatment Selection in Myositis [0.03%]
自身抗体在肌炎治疗选择中的作用
Maria Casal-Dominguez,Iago Pinal-Fernández,Andrew L Mammen
Maria Casal-Dominguez
Purpose of review: Autoimmune myopathies (IMs) are a group of diseases characterized by muscle weakness and inflammatory infiltrates on the muscle biopsy. 'However, muscle involvement is not always present and other organ...
Albert Selva-O&#x;Callaghan,Ernesto Trallero-Araguás,Albert Gil-Vila et al.
Albert Selva-O&#x;Callaghan et al.
Purpose of review: Eosinophilic fasciitis (EF) is a rare inflammatory disease characterized by skin induration. Although some guidelines from scientific societies exist, standard recommendations on monitoring and therapy ...
Treatment of rheumatoid arthritis-associated interstitial lung disease: An appraisal of the 2023 ACR/CHEST guideline [0.03%]
美国风湿病学会/美国胸科医师学会关于类风湿关节炎相关间质性肺疾病的治疗指南(2023年)解读
Alene A Saavedra,Kevin T Mueller,Emily N Kowalski et al.
Alene A Saavedra et al.
Purpose of review: To summarize the current treatment landscape of rheumatoid arthritis-associated interstitial lung disease (RA-ILD) in the context of the recent 2023 American College of Rheumatology/American College of ...
A Selva-O&#x;Callaghan,A Guillen-Del-Castillo,A Gil-Vila et al.
A Selva-O&#x;Callaghan et al.
Purpose of review: Systemic sclerosis (SSc) and myositis are two different entities that may coexist as an overlap syndrome. Immunological biomarkers such as anti-PM/Scl or anti-Ku reinforce the syndrome. This review is f...
Melody P Chung,Julie J Paik
Melody P Chung
Purpose of review: This review highlights current and emerging pharmacologic therapies for the treatment of dermatomyositis (DM). Current clinical evidence, in addition to recently published and ongoing clinical trials fo...