MSA-Net: a multi-scale and adversarial learning network for segmenting bone metastases in low-resolution SPECT imaging [0.03%]
MSA-Net:一种用于低分辨率SPECT影像中骨转移灶分割的多尺度对抗学习网络
Yusheng Wu,Qiang Lin,Yang He et al.
Yusheng Wu et al.
Background: Single-photon emission computed tomography (SPECT) plays a crucial role in detecting bone metastases from lung cancer. However, its low spatial resolution and lesion similarity to benign structures present sig...
Feasibility of in vivo small animal imaging using a clinical total-body PET/CT system [0.03%]
临床全身PET/CT系统的小动物成像可行性研究
Julia G Mannheim,Wenhong Lan,Maurizio Conti et al.
Julia G Mannheim et al.
Background: Clinical PET scanners have long been explored for preclinical imaging, but limited spatial resolution and sensitivity have restricted their use for preclinical studies. The recent availability of total-body (T...
Modeling of a population-based input function (PBIF) using the Feng model in dynamic ⁶⁸Ga-DOTATOC whole body PET/CT scans: feasibility of shortened imaging protocols on PET/CT Vision 600 system ® [0.03%]
基于人群的输入函数(PBIF)在动态⁶⁸Ga-DOTATOC全身PET/CT扫描中的Feng模型建模:在PET/CT Vision 600系统上缩短成像协议的可行性研究
Thomas Godefroy,Mathieu Pavoine,David Bourhis et al.
Thomas Godefroy et al.
Background: This study focuses on modeling a population-based input function (PBIF) in dynamic ⁶⁸Ga-DOTATOC PET/CT exams, with the aim of developing clinically adoptable protocols. The PBIF is derived from an image-deri...
Assessment and clinical relevance of pulmonary shunt on 166Ho-Scout Imaging in hepatocellular carcinoma [0.03%]
166霍噠肺灌注显像评价及肺通气/血流灌注异常的临床意义
Evelyn Vranken,An De Crop,Victor Nuttens et al.
Evelyn Vranken et al.
Aim: Prediction of posttreatment lung mean dose (LMD) during liver radioembolization (RE) work-up is essential for risk evaluation of radiation pneumonitis, especially when treating large hepatocellular carcinoma (HCC) wh...
Effect of data-driven motion correction for respiratory movement on lesion detectability in PET-CT: a phantom study [0.03%]
基于数据驱动运动校正的呼吸运动对PET/CT病灶检出性能的影响研究:体模实验
Marloes A de Winter,Robin Gevers,Jules Lavalaye et al.
Marloes A de Winter et al.
Purpose: While data-driven motion correction (DDMC) techniques have proven to enhance the visibility of lesions affected by motion, their impact on overall detectability remains unclear. This study investigates whether DD...
S-values for bone marrow dosimetry in preclinical radiopharmaceutical studies with rodents [0.03%]
用于放射性药物预临床研究的小鼠和大鼠骨髓剂量学S值
Mohammed Obaid,Arman Rahmim,William P Segars et al.
Mohammed Obaid et al.
Background: Development of novel radiopharmaceuticals involves dosimetry calculations to validate safety and aid with selection of those that should be translated into the clinical environment. Dosimetry is critical for l...
Evaluation of using small volume of interest regions for clinical kidney dosimetry in 177Lu-DOTATATE treatments [0.03%]
评估在177Lu-DOTATATE治疗中使用小体积感兴趣区域进行临床肾脏剂量学评价的方法
Jehangir Khan,Tobias Rydèn,Martijn Van Essen et al.
Jehangir Khan et al.
Segmentation of the whole-kidney parenchyma (WKP) is considered the reference method for kidney dosimetry of radiopharmaceuticals, as it provides the average absorbed dose to the fully delineated WKP. However manual segmentation of the WKP ...
Evaluation of relative biological effectiveness of 225Ac and its decay daughters with Monte Carlo track structure simulations [0.03%]
基于蒙特卡洛径迹结构模拟的225Ac及其衰变子体相对生物效应评价
Ziyi Hu,Shuiyin Qu,Hongming Liu et al.
Ziyi Hu et al.
Background: 225Ac is a radionuclide that can be utilized in targeted alpha therapy (TAT). To accurately assess the absorbed dose and radiation effects in TAT, it is necessary to calculate the relative biological effective...
Dosimetric study on radioembolization with 166Ho poly L-lactic acid microspheres: dead time effects on prediction power [0.03%]
166霍物理聚L-乳酸微球放射栓塞的定量化研究:死时间对预测能力的影响
Bartolomeo Cassano,Ludovica Miseo,Sara Ungania et al.
Bartolomeo Cassano et al.
Background: 166Ho-poly-L-lactic acid microspheres (166Ho-PLLA) offer the advantage of using the same microspheres for both Scout and Therapeutic Administrations (SA and TA) in radioembolization compared to 90Y. This study...
Comparison of tumour segmentation methods for dosimetry in [177Lu]Lu-PSMA I&T treated patients with metastatic castration resistant prostate cancer [0.03%]
[177Lu]Lu-PSMA I&T治疗转移性去势抵抗性前列腺癌的患者剂量学肿瘤分割方法比较
Peter Frøhlich Staanum,Peter Iversen
Peter Frøhlich Staanum
Background: Tumour dosimetry after radionuclide therapy using 177Lu-labelled radiopharmaceuticals requires determination of the 177Lu mean concentration, but this is challenging as tumours are often small, or 177Lu activi...