Clinical spectrum of α-Gal syndrome: from immediate-type to delayed immediate-type reactions to mammalian innards and meat [0.03%]
α-半乳糖综合征的临床谱系：从对哺乳动物内脏和肉类的即时型反应到延迟性即时型反应
Jörg Fischer,Amir S Yazdi,Tilo Biedermann
Jörg Fischer
The term α-Gal syndrome describes a novel IgE-mediated immediate-type allergy to the disaccharide galactose-α-1,3-galactose (α-Gal). Its classification as a syndrome is proposed on the basis of its clinical relevance in three different f...
Evidence vs. efficacy in allergen-specific immunotherapy: Considerations using the example of tradable products in Germany [0.03%]
过敏原特异性免疫疗法中的证据与疗效：以德国可交易产品为例的考量因素
Randolf Brehler,Ludger Klimek,Christian Vogelberg et al.
Randolf Brehler et al.
The recently published S2k-guideline on (allergen-) specific immunotherapy (AIT) provides an excellent overview of the evidence on allergen preparations available for AIT in Germany based on the published efficacy studies. Publications base...
Ambrosia artemisiifolia (ragweed) in Germany - current presence, allergological relevance and containment procedures [0.03%]
德国的艾菊（豚草）- 当前分布、致敏性及相关防控措施
Jeroen Buters,Beate Alberternst,Stefan Nawrath et al.
Jeroen Buters et al.
Ambrosia artemisiifolia (ragweed) is a neophyte in Europe and Germany, which originated from the United States of America. In the USA the rate of sensitization against ragweed equals that of grass pollen, and without containment the rate of...
Marek Lommatzsch,Paul Stoll
Marek Lommatzsch
Novel treatment strategies are currently emerging for patients with inadequately controlled asthma despite good adherence and trigger avoidance. These strategies serve primarily to reduce or completely avoid long-term oral corticosteroid th...
Current status of allergy prevalence in Germany: Position paper of the Environmental Medicine Commission of the Robert Koch Institute [0.03%]
德国过敏症流行现状：罗伯特·科赫研究所环境医学委员会立场文件
Karl-Christian Bergmann,Joachim Heinrich,Hildegard Niemann
Karl-Christian Bergmann
The lifetime prevalence of allergic diseases in adults in Germany [self-reported doctor diagnosed allergic diseases, Study on Adult Health in Germany (Studie zur Gesundheit Erwachsener in Deutschland, DEGS1, 2008-2011) of the Robert Koch In...
Molecular allergy diagnostics using multiplex assays: methodological and practical considerations for use in research and clinical routine: Part 21 of the Series Molecular Allergology [0.03%]
分子过敏诊断中多联检测方法的应用：在研究和临床常规应用中的方法学及实践问题：系列文章《分子过敏学》第21部分
Thilo Jakob,Peter Forstenlechner,Paolo Matricardi et al.
Thilo Jakob et al.
The availability of single allergens and their use in microarray technology enables the simultaneous determination of specific IgE (sIgE) to a multitude of different allergens (> 100) in a multiplex procedure requiring only minute amounts o...
13-year overview of serious adverse drug reactions following subcutaneous specific immunotherapy with a chemically modified allergen preparation [0.03%]
改良制剂变应原皮下免疫治疗严重不良反应13年回顾性分析
Andreas Distler,Debbie Pappelendam
Andreas Distler
Background: The Paul-Ehrlich-Institut (PEI) published an analysis of reports of adverse drug reactions (ADRs) in 2001 with test and therapy allergens from the period from 1991 to 2000. Possible risk factors were evaluated...
Guidelines on the management of IgE-mediated food allergies: S2k-Guidelines of the German Society for Allergology and Clinical Immunology (DGAKI) in collaboration with the German Medical Association of Allergologists (AeDA), the German Professional Association of Pediatricians (BVKJ), the German Allergy and Asthma Association (DAAB), German Dermatologic [0.03%]
德国变态反应学和临床免疫学会(IgE介导的食物过敏诊疗指南)
Margitta Worm,Imke Reese,Barbara Ballmer-Weber et al.
Margitta Worm et al.
Spiking with recombinant allergens to improve allergen extracts: benefits and limitations for the use in routine diagnostics: Part 19 of the Series Molecular Allergology [0.03%]
使用重组过敏原进行强化以改进过敏原提取物：在常规诊断中的应用及其局限性——系列文章《分子过敏学》第19部分
Johannes Huss-Marp,Monika Raulf,Thilo Jakob
Johannes Huss-Marp
Essentially, allergen components offer three possibilities to improve in vitro IgE diagnostics: Allergen components can be used individually for IgE determination.Allergen components can be combined as a mix in one test.Individual allergen ...
Molecular allergy diagnostics using IgE singleplex determinations: methodological and practical considerations for use in clinical routine: Part 18 of the Series Molecular Allergology [0.03%]
使用IgE单因子测定进行分子过敏诊断：在临床常规应用中的方法学及实践问题探讨（系列文章分子过敏学第18部分）
Jörg Kleine-Tebbe,Thilo Jakob
Jörg Kleine-Tebbe
Allergen molecules (synonyms: single allergens, allergen components) open up new horizons for the targeted allergen-specific diagnostics of immunoglobulin E (IgE) in singleplex determination. The following rationales support the targeted us...