Idiopathic Anaphylaxis [0.03%]
特发性过敏反应
Bright I Nwaru,Sangeeta Dhami,Aziz Sheikh
Bright I Nwaru
Idiopathic anaphylaxis is a rare life-threatening disorder with symptoms similar to other forms of anaphylaxis. There is lack of a robust evidence base underpinning the treatment of anaphylaxis and even less so for idiopathic anaphylaxis. M...
Agnieszka Lipińska-Ojrzanowska,Andrzej Marcinkiewicz,Jolanta Walusiak-Skorupa
Agnieszka Lipińska-Ojrzanowska
Determination of biomarkers may be useful in the surveillance of occupational exposure and workers' health. The possibility of predicting development/clinical course of specific disorders or current disease, diagnosing in early steps, and h...
Update on Biomarkers to Monitor Clinical Efficacy Response During and Post Treatment in Allergen Immunotherapy [0.03%]
allergen免疫治疗过程中和治疗后监测临床疗效反应的生物标志物的研究进展
Lubna Kouser,Jasper Kappen,Ross P Walton et al.
Lubna Kouser et al.
Allergen immunotherapy (AIT) is an immune modulating treatment for allergic diseases. Although highly effective, some patients do not respond to the treatment. To date there are no surrogate biomarkers that are predictive of the clinical re...
Rekha D Jhamnani,Pamela Frischmeyer-Guerrerio
Rekha D Jhamnani
Immunotherapy for peanut allergy has been an exploding topic of study within the last few years. Sublingual, epicutaneous, and oral immunotherapy are being investigated and show promise in the treatment of peanut allergy. Oral immunotherapy...
Pediatric Rhinosinusitis [0.03%]
儿童鼻窦炎
Dana T Badr,Jonathan M Gaffin,Wanda Phipatanakul
Dana T Badr
Rhinosinusitis, is defined as an inflammation of the paranasal and nasal sinus mucosae. Chronic rhinosinusitis (CRS)is a common problem in the pediatric age group and the diagnosis and treatment are challenging due to the chronicity and sim...
Merel C Onnes,Luciana K Tanno,Joanne N G Oude Elberink
Merel C Onnes
Mast cell clonal disorders are characterized by the clonal proliferation of pathological mast cells as a result of somatic mutations in the KIT gene, most commonly the D816V mutation. Accumulation and degranulation of these cells causes a w...
Anna James,Gunilla Hedlin
Anna James
An important issue in relation to the utility and reliability of biomarkers for asthma monitoring is how asthma is defined and characterized. What kind of asthma, or at what stage of the disease is a particular biomarker supposed to add inf...
Christian Lupinek,Eva Wollmann,Rudolf Valenta
Christian Lupinek
Allergen-specific immunotherapy (AIT) is the only treatment of IgE-mediated allergies so far that has a sustained effect on clinical symptoms and can modify the course of the disease. It is an allergen-specific treatment and therefore requi...
Using Component-Resolved Diagnostics in the Management of Peanut-Allergic Patients [0.03%]
用于花生过敏患者的分组诊断管理方法
F C van Erp,R J B Klemans,Y Meijer et al.
F C van Erp et al.
Instead of relying on crude peanut extract, component-resolved diagnostics (CRD) uses sensitization to allergenic proteins within peanut. In this review, we describe the recent advances and future perspectives of the use of CRD in the manag...
Mite-Allergic Rhinitis: How to Evaluate Clinical Efficacy in Allergen-Specific Immunotherapy Trials? [0.03%]
尘螨过敏性鼻炎：如何评估免疫治疗临床疗效？
Oliver Pfaar,Roy Gerth van Wijk
Oliver Pfaar
House dust mite (HDM) allergen exposure is the most important cause of perennial allergic rhinitis and/or asthma. Although allergen-specific immunotherapy (AIT) with HDM is well established, published studies have been characterized by subs...