Dominic A Boardman,Jacinta Jacob,Lesley A Smyth et al.
Dominic A Boardman et al.
Direct allorecognition is the process by which donor-derived major histocompatibility complex (MHC)-peptide complexes, typically presented by donor-derived 'passenger' dendritic cells, are recognised directly by recipient T cells. In this r...
Hrishikesh S Kulkarni,Bradford C Bemiss,Ramsey R Hachem
Hrishikesh S Kulkarni
There has been increasing awareness of antibody-mediated rejection (AMR) as an important cause of graft failure after lung transplantation in recent years. However, the diagnostic criteria for pulmonary AMR are not well defined. All four te...
Acute Antibody-Mediated Rejection in Renal Transplantation: Current Clinical Management [0.03%]
肾移植急性抗体介导排斥反应的临床诊治进展
Carrie Schinstock,Mark D Stegall
Carrie Schinstock
Acute antibody mediated rejection (AMR) is recognized as a major cause of graft loss in renal transplant recipients. Early acute AMR in the first few days after transplantation occurs primarily in sensitized renal transplant recipients with...
Bettina Wilm,Riccardo Tamburrini,Giuseppe Orlando et al.
Bettina Wilm et al.
Worldwide, increasing numbers of patients are developing end-stage renal disease, and at present, the only treatment options are dialysis or kidney transplantation. Dialysis is associated with increased morbidity and mortality, poor life qu...
Educating Prospective Kidney Transplant Recipients and Living Donors about Living Donation: Practical and Theoretical Recommendations for Increasing Living Donation Rates [0.03%]
提高活体捐赠率的实用和理论建议——教育潜在的肾移植受者和活体捐献人了解活体捐赠事项
Amy D Waterman,Mark L Robbins,John D Peipert
Amy D Waterman
A promising strategy for increasing living donor kidney transplant (LDKT) rates is improving education about living donation for both prospective kidney transplant recipients and living donors to help overcome the proven knowledge, psycholo...
Early Graft Dysfunction in Living Donor Liver Transplantation and the Small for Size Syndrome [0.03%]
活体肝移植术后早期移植物功能障碍与小肝脏综合征的关系研究
Jay A Graham,Benjamin Samstein,Jean C Emond
Jay A Graham
LDLT has arisen as a viable means to reduce waitlist mortality. However, its widespread embrace by the liver transplant community has been met with frustration centered on donor morbidity and small-for-size-syndrome. Focusing on the later e...
Glomerular Function and Structure in Living Donors: Lessons from Single Nephron Studies [0.03%]
单肾小管研究对活体供者的肾功能及结构的启示作用
Colin R Lenihan,Bryan D Myers,Jane C Tan
Colin R Lenihan
One third of the kidney transplants performed in the USA come from living kidney donors. The long-term outcome of healthy individuals who donate kidneys is mostly excellent, although recent studies have suggested that living donation is ass...
Vichin Puri,James Eason
Vichin Puri
In 2014, simultaneous liver kidney transplants (SLK) accounted for 8.2 % of all liver transplants performed in the USA. Prior to introduction of the model of end stage liver disease (MELD) system, SLK accounted for 2.5 % in 2001 and only 1....
New Tools in Experimental Cellular Therapy for the Treatment of Liver Diseases [0.03%]
实验细胞疗法治疗肝病的新工具
Jennifer R Ferrer,Attasit Chokechanachaisakul,Jason A Wertheim
Jennifer R Ferrer
The current standard of care for end stage liver disease is orthotopic liver transplantation (OLT). Through improvement in surgical techniques, immunosuppression, and general medical care, liver transplantation has become an effective treat...
Jordi Ochando,Patricia Conde,Vincenzo Bronte
Jordi Ochando
Myeloid-derived suppressor cells (MDSC) are cells of myeloid origin with enhanced suppressive function. They are negative regulators of the immune responses and comprise a heterogeneous mixture of immunosuppressive cells of monocytic (M-MDS...