William S Oetting,Casey Dorr,Rory P Remmel et al.
William S Oetting et al.
Purpose of review: Identification of genetic variants to aid in individualized treatment of solid organ allograft recipients would improve graft survival. We will review the current state of knowledge for associations of ...
Negin Karimian,Heidi Yeh
Negin Karimian
Purpose of review: There is a vast discrepancy between the number of patients waiting for organ transplantation and the available donor organs. Ex vivo machine perfusion (MP) has emerged in an effort to expand the donor p...
Nanotechnological Approaches to Immunosuppression and Tolerance Induction [0.03%]
纳米技术在免疫抑制和耐受诱导中的应用
Kunal Patel,Carl Atkinson,Danh Tran et al.
Kunal Patel et al.
Purpose of review: Several preclinical studies have engineered nanoparticles for immune regulation, and have shown promising results in the fields of autoimmunity and cancer. In solid organ transplantation, the use of nan...
Vrushali V Agashe,William J Burlingham
Vrushali V Agashe
Organ transplantation is the only viable treatment for several end-stage organ failures. However chronic rejection prevents long-term graft survival. Traditionally this rejection was attributed to the development of alloimmunity in transpla...
Jennifer C Gander,Elisa J Gordon,Rachel E Patzer
Jennifer C Gander
Purpose of review: For the more than 636,000 adults with end-stage renal disease (ESRD) in the U.S., kidney transplantation is the preferred treatment compared to dialysis. Living donor kidney transplantation (LDKT) compr...
Xenotransplantation: Where Are We with Potential Kidney Recipients? Recent Progress and Potential Future Clinical Trials [0.03%]
异种移植：潜在的肾脏受者的现状近期进展和未来临床试验的潜力
Kazuhiko Yamada,Jigesh A Shah,Tatsu Tanabe et al.
Kazuhiko Yamada et al.
Purpose: Inter-species transplantation, xenotransplantation, is becoming a realistic strategy to solve the organ shortage crisis. Here we focus on seminal publications that have driven research in xenotransplantation, as ...
Measuring transplant center performance: The goals are not controversial but the methods and consequences can be [0.03%]
移植中心绩效评估：目标无争议 方法和结果有争议
Colleen Jay,Jesse D Schold
Colleen Jay
Purpose of review: Risks of regulatory scrutiny has generated widespread concern about increasingly risk averse transplant center behaviors regarding both donor and candidate acceptance patterns. To address potential unin...
Wayne M Tsuang
Wayne M Tsuang
Purpose of review: To discuss the current state of donor lung allocation in the United States, and future opportunities to increase the efficiency of donor lung allocation. ...
Strategies for assessing GFR and albuminuria in the living kidney donor evaluation [0.03%]
活体肾脏捐献者评估中评价肾小球滤过率和白蛋白尿的策略
Lesley A Inker,Naya Huang,Andrew S Levey
Lesley A Inker
Purpose of review: The international guideline development group Kidney Disease Improving Global Outcomes (KDIGO) recently published a comprehensive set of recommendations for living donor evaluation which contains a new ...
Extracorporeal Membrane Oxygenation (ECMO) and the Critical Cardiac Patient [0.03%]
体外膜氧合(ECMO)与心脏重症患者监护
David A Baran
David A Baran
Purpose of review: This review is to summarize the basics of veno-arterial (VA) extracorporeal membrane oxygenation (ECMO) as it is utilized for critically ill cardiac patients. ...