Pushing the Limits: Machine Preservation of the Liver as a Tool to Recondition High-Risk Grafts [0.03%]
突破极限:器官机保存技术作为重塑高风险移植物的工具
Yuri L Boteon,Simon C Afford,Hynek Mergental
Yuri L Boteon
Purpose of the review: Machine perfusion (MP) is a novel technology recently introduced in liver transplantation, redefining the current practice of organ preservation and pushing the limits of high-risk liver utilisation...
Olivia N Gilbert,Patricia P Chang
Olivia N Gilbert
A purpose of review: This review summarizes recent data about antibodies after cardiac transplantation; what testing modalities are available and how frequently to employ them; as well as when treatment is necessary. ...
James E Squires,Kyle A Soltys,Patrick McKiernan et al.
James E Squires et al.
Purpose of review: Significant recent scientific developments have occurred in the field of liver repopulation and regeneration. While techniques to facilitate liver repopulation with donor hepatocytes and different cell ...
Carlo D L Ceresa,David Nasralla,Wayel Jassem
Carlo D L Ceresa
Purpose of review: This review aims to introduce the concept of normothermic machine perfusion (NMP) and its role in liver transplantation. By discussing results from recent clinical studies and highlighting the potential...
Andrea Schlegel,Xavier Muller,Philipp Dutkowski
Andrea Schlegel
Purpose of review: In this review, we highlight which livers may benefit from additional treatment before implantation and describe the concept of hypothermic machine liver perfusion. Furthermore, we explain why cold oxyg...
From "Gut Feeling" to Objectivity: Machine Preservation of the Liver as a Tool to Assess Organ Viability [0.03%]
从"直觉"到客观性:利用机器保存肝脏以评估器官活力
Christopher J E Watson,Ina Jochmans
Christopher J E Watson
Purpose of review: The purpose of this review was to summarise how machine perfusion could contribute to viability assessment of donor livers. Recent find...
Elena Garreta,Sonia Sanchez,Jeronimo Lajara et al.
Elena Garreta et al.
Purpose of review: The goal of this paper is to highlight the major challenges in the translation of human pluripotent stem cells into a clinical setting. ...
Simultaneous Liver-Kidney Transplantation: Impact on Liver Transplant Patients and the Kidney Transplant Waiting List [0.03%]
肝肾联合移植:对肝移植受者和肾脏移植等待名单的影响
Clifford D Miles,Scott Westphal,AnnMarie Liapakis et al.
Clifford D Miles et al.
Purpose: The number of simultaneous liver-kidney transplants (SLKT) performed in the USA has been rising. The Organ Procurement and Transplantation Network implemented a new policy governing SLKT that specifies eligibilit...
Vasishta S Tatapudi,Robert A Montgomery
Vasishta S Tatapudi
Purpose of review: Over the past two decades, significant strides made in our understanding of the etiology of antibody-mediated rejection (AMR) in transplantation have put the complement system in the spotlight. Here, we...
Donation, Not Disease! A Multiple-Hit Hypothesis on Development of Post-Donation Kidney Disease [0.03%]
捐献而非疾病!关于捐后肾脏疾病的多因素假设
Xingxing S Cheng,Richard J Glassock,Krista L Lentine et al.
Xingxing S Cheng et al.
Purpose of review: The risks following living kidney donation has been the subject of rigorous investigation in the past several decades. How to utilize the burgeoning new knowledge base to better the risk assessment, edu...