Philipp de Leuw,Christoph Stephan
Philipp de Leuw
The hepatitis C virus (HCV) has affected an estimate of 80 million individuals worldwide and is a strain of public health. Around 25-30% of patients in Europe and the US infected with HIV are coinfected with HCV. Despite treatment modalitie...
Intestinal carriage of multidrug-resistant bacteria among healthcare professionals in Germany [0.03%]
德国医疗专业人员多重耐药肠道细菌携带状况
Katalin Jozsa,Katja de With,Winfried Kern et al.
Katalin Jozsa et al.
Healthcare professionals (HCP) might be at increased risk of acquisition of multidrug-resistant bacteria (MDRB), i.e., methillicin-resistant Staphy l oc occus aureus (MRSA), vancomycin-resistant enterococci (VRE), and multidrug-resistant gr...
Spectrum and antibiotic resistance of catheter-associated urinary tract infections [0.03%]
导管相关尿路感染的病原体及其对抗菌药物的耐药性分析
Béla Köves,András Magyar,Peter Tenke
Béla Köves
Catheter associated urinary tract infections (CAUTIs) are amongst the most common nosocomial infections and are also considered among the most common complications associated with indwelling urinary catheters. Most catheter associated infec...
Invasion of HEp-2 cells by Shigella spp. isolated from acute pediatric diarrhea [0.03%]
宋内志贺菌对急性儿科腹泻患者分离的致病性细菌的侵染作用
Sajjad Omidi,Mohammad Mehdi Soltan Dallal,Abolfazle Davoodabadi et al.
Sajjad Omidi et al.
Aim: Shigella infection is an important global health problem in developing countries where hygiene is poor and hence shigellosis is a main cause of diarrhoea-associated mortality and morbidity, particularly in children under the age of fiv...
Susanne Duwe
Susanne Duwe
Influenza is a serious and frequently underestimated, but vaccine preventable disease. The adamantane derivates rimantadine and amantadine and the neuraminidase inhibitors zanamivir and oseltamivir are the only antiviral drugs currently app...
Christoph Dorn,Hartmuth Nowak,Caroline Weidemann et al.
Christoph Dorn et al.
The mean (SD) unbound fraction of moxifloxacin in plasma from patients with severe sepsis or septic shock was determined by ultrafiltration to 85.5±3.0% (range 81.9 and 91.6%) indicating a decreased protein binding of moxifloxacin in this ...
Treatment of MRSA pneumonia: Clinical and economic comparison of linezolid vs. vancomycin - a retrospective analysis of medical charts and re-imbursement data of real-life patient populations [0.03%]
耐甲氧西林金黄色葡萄球菌肺炎的治疗：利奈唑胺与万古霉素的临床及经济效益对比-真实世界人群病例分析及理赔数据回顾
Michael H Wilke,Karsten Becker,Sebastian Kloss et al.
Michael H Wilke et al.
Objectives: To supplement the data collected in randomized clinical trials, the present study in patients with methicillin resistant Staphylococcus aureus (MRSA) pneumonia was conducted to explore the clinical effectiveness of linezolid and...
Comprehensive diagnosis and treatment of alveolar echinococcosis: A single-center, long-term observational study of 312 patients in Germany [0.03%]
德国单中心肺棘球蚴病综合诊断和治疗的长期观察研究(312例报告)
Beate Grüner,Petra Kern,Benjamin Mayer et al.
Beate Grüner et al.
Alveolar echinococcosis (AE) is the most Iethal human helminthic infection. The malignancy-like disease is rare, but morbidity and treatment costs are high. Objective of the study was to identify factors at baseline and during specific AE t...
Zincophorin - biosynthesis in Streptomyces griseus and antibiotic properties [0.03%]
链霉菌素灰色链霉菌中的锌霉素-生物合成及抗生素特性
Elisabeth Walther,Sabrina Boldt,Hirokazu Kage et al.
Elisabeth Walther et al.
Zincophorin is a polyketide antibiotic that possesses potent activity against Gram-positive bacteria, including human pathogens. While a number of total syntheses of this highly functionalized natural product were reported since its initial...
Temporal trends of the in vitro activity of tigecycline and comparator antibiotics against clinical aerobic bacterial isolates collected in Germany, 2006-2014: results of the Tigecycline Evaluation and Surveillance Trial (TEST) [0.03%]
我国成人社区获得性呼吸道感染流感病毒耐药性的流行病学特征分析
Michael Kresken,Barbara Körber-Irrgang,Christian Petrik et al.
Michael Kresken et al.
Given the rapidly changing landscape of antimicrobial resistance, continuous monitoring of antimicrobial susceptibility in clinically relevant bacterial isolates plays an important role in the management of infectious diseases. The Tigecycl...