TGFβ depletion does neither modulate acute E. coli-induced inflammatory immune responses nor impair the protective effect by chronic filarial infection [0.03%]
TGFβ耗竭不会调节急性大肠杆菌诱导的炎症免疫反应，也不会损害慢性丝虫感染产生的保护作用
Benedikt C Buerfent,Jesuthas Ajendra,Wiebke Stamminger et al.
Benedikt C Buerfent et al.
TGFβ is an anti-inflammatory molecule that suppresses pro-inflammatory immune responses. Previously, we demonstrated that chronic filarial infection has a beneficial impact on Escherichia coli-induced sepsis. In the present study, we inves...
Potential savings through single-dose intravenous Dalbavancin in long-term MRSA infection treatment - a health economic analysis using German DRG data [0.03%]
万古霉素治疗长期耐甲氧西林金黄色葡萄球菌感染的单剂量达巴万星静脉注射潜在节约分析-使用德国DRG数据进行的卫生经济学分析
Michael Wilke,Kerstin Worf,Birgit Preisendörfer et al.
Michael Wilke et al.
Complicated infections such as osteomyelitis, skin and soft tissue infections or endocarditis often require antibiotic therapies that can last up to several weeks. The prolonged hospital length of stay (LOS) leads to a dramatic increase in ...
Herbert Hof
Herbert Hof
Rhodotorula spp. belong to the basidiomyceteous fungi. They are widespread in the environment. Transmission to humans occur mainly through air and food. Intestinal colonization is rather common, but an overgrowth is normally suppressed, sin...
Evaluation of a new combined Western and line blot assay (EUROLINE-WB) for diagnosis and species identification of Echinococcus infection in humans [0.03%]
评估新型西方和线条免疫印迹组合试验（EUROLINE-WB）在人类棘球蚴病诊断及分型中的应用价值
Susanne Deininger,Nele Wellinghausen
Susanne Deininger
Serological detection of echinococcosis is crucial for diagnosis and management. We evaluated the new blot assay Euroline-WB (ELB, Euroimmun) which consists of a Western blot with Echinococcus multilocularis (E.m.) vesicle antigens and a li...
Antibiotic consumption and resistance of gram-negative pathogens (collateral damage) [0.03%]
抗生素消耗和革兰氏阴性病原体的耐药性（附带损害）
Milan Cižman,Tina Plankar Srovin
Milan Cižman
Antibiotics are commonly prescribed in community and hospital care. Overuse and misuse favors emergence and spread of resistant bacteria. The ATC/DDD methodology is commonly used for presenting the drug utilization data. In primary care, th...
Christian Wejse
Christian Wejse
Urogenital tuberculosis (UGTB) should in general be treated as pulmonary TB with a four-drug regimen of Isoniazid, Rifampicin, Ethambutol and Pyrazinamide for a total of 6 months, Ethambutol and Pyrazinamide only the first two months. Some ...
Clinical characteristics of a large cohort of patients with positive culture of Fusobacterium necrophorum [0.03%]
具芽孢弗索菌培养阳性的大量患者的临床特征
Romana Klasinc,Kostiantyn Lupyr,Iris Zeller et al.
Romana Klasinc et al.
Background: Fusobacterium necrophorum is a rare pathogen, mostly affecting young adults, causing infections of the head and neck, typically described as the Lemierre's syndrome. Today this symptom complex has become increasingly rare and ha...
Influenza vaccination coverage of health care workers: a cross-sectional study based on data from a Swiss gynaecological hospital [0.03%]
基于瑞士妇产科医院数据的医务人员流感疫苗接种情况横断面研究
Evelyn Dass von Perbandt,René Hornung,Mirjam Thanner
Evelyn Dass von Perbandt
Background: Pregnancy is a risk factor for severe influenza and related complications. The vaccination has been recommended in healthcare workers as a strategy for preventing influenza in risk patients. The aim of this study was to analyze ...
Anti-tubercular activity of a natural stilbene and its synthetic derivatives [0.03%]
一种天然茋类化合物及其合成衍生物的抗结核活性研究
Claudia Reinheimer,Dominik Büttner,Eugen Proschak et al.
Claudia Reinheimer et al.
Objectives: Tuberculosis (TB) and multidrug- and extensively drug-resistant TB in particular are remaining a major global health challenge and efficient new drugs against TB are needed. This study evaluated the anti-tubercular activity of a...
Asymptomatic bacteriuria in recurrent UTI - to treat or not to treat [0.03%]
复发性尿路感染合并无症状菌尿是治疗还是不治疗？
Tommaso Cai,Riccardo Bartoletti
Tommaso Cai
Asymptomatic bacteriuria (ABU) is a common clinical condition that often leads to unnecessary antimicrobial use. The reduction of antibiotic overuse for ABU is consequently an important issue for antimicrobial stewardship to reduce the emer...