AWaRe-based culture reporting format: a novel tool for antimicrobial stewardship [0.03%]
基于AWaRe的文化报告格式：抗菌药物管理的新工具
Heera Hassan,Jyothi R,Sreenadh H et al.
Heera Hassan et al.
Comparison of Treponema-specific immunoglobulin G (IgG) index with Treponema pallidum particle agglutination (TPPA) index for detection of intrathecal Treponema-specific antibody synthesis for serological diagnosis of neurosyphilis [0.03%]
钩端螺旋体特异性免疫球蛋白G指数与梅毒螺旋体颗粒凝集试验指数在血清学诊断神经梅毒检测脑脊液中钩端螺旋体特异性抗体合成的比较研究
Nele Wellinghausen,Andrea Götz,Teresa Esthela Rangel Vivar
Nele Wellinghausen
The determination of Treponema-specific intrathecal immunoglobulin synthesis with the Treponema pallidum particle agglutination (TPPA) index is a well-established method recommended in German guidelines for the diagnosis of neurosyphilis. H...
COVID-19 treatment strategies with drugs centrally procured by the German Federal Ministry of Health in a representative tertiary care hospital: a temporal analysis [0.03%]
德国联邦卫生部集中采购的药物治疗方案在一家有代表性的三级护理医院中用于治疗COVID-19：时序分析
Kathrin Marx,Sven Kalbitz,Nils Kellner et al.
Kathrin Marx et al.
Introduction: To ensure the fastest and earliest possible treatment, the German Federal Ministry of Health (BMG) initiated central procurement and nationwide distribution of new drugs against COVID-19. A single centre was...
Dynamics of immunity over time: decline of anti-SARS-CoV-2 IgG antibodies and T-cell responses after mRNA vaccination in residents and health care workers in nursing homes and homes with assisted living support [0.03%]
随时间推移免疫动态变化：养老院和辅助生活支持机构中居民和工作人员接种信使核糖核酸疫苗后抗SARS-CoV-2 IgG抗体和T细胞应答的下降
Julia Schiffner,Nora Eisemann,Hannah Baltus et al.
Julia Schiffner et al.
Background: In the present study, we investigated the dynamics of immunity over time by measuring anti SARS-CoV-2 IgG antibodies and SARS-CoV-2 specific T-cell responses (interferon-gamma release assay) after two doses of...
Current perspective of new anti-Wolbachial and direct-acting macrofilaricidal drugs as treatment strategies for human filariasis [0.03%]
新型抗沃尔巴克体和直接杀死丝虫成虫药物治疗策略的人类(filariasis)现况展望
Alexandra Ehrens,Achim Hoerauf,Marc P Hübner
Alexandra Ehrens
Filarial diseases like lymphatic filariasis and onchocerciasis belong to the Neglected Tropical Diseases and remain a public health problem in endemic countries. Lymphatic filariasis and onchocerciasis can lead to stigmatizing pathologies a...
Psychosocial burden of recurrent uncomplicated urinary tract infections [0.03%]
反复发作的单纯性泌尿系感染的心理社会负担
Kurt G Naber,José Tirán-Saucedo,Florian M E Wagenlehner;RECAP group
Kurt G Naber
Introduction: Urinary tract infections (UTI) are a leading cause of bacterial infections in women. Despite acute treatment, 30-50% of women who have a UTI will experience a recurrence within 6-12 months. In this review, the focus will be on...
Bacterial infections in patients with nipple piercings: a qualitative systematic review of case reports and case series [0.03%]
乳头穿孔患者细菌感染的病例报告和案例系列的定性系统评价
Luis M Acuña-Chávez,Christian A Alva-Alayo,Giamfranco A Aguilar-Villanueva et al.
Luis M Acuña-Chávez et al.
The main objective of this review is to identify the most frequently isolated bacteria in patients with infections related to nipple piercings in case reports and case series. In addition, the aim is to describe clinical manifestations and ...
Comparative in vitro activity of piperacillin-tazobactam and temocillin against third-generation cephalosporin-resistant, carbapenem-susceptible Escherichia coli and Klebsiella pneumoniae [0.03%]
哌拉西林他唑巴坦和替莫西林对第三代头孢菌素耐药、碳青霉烯类敏感的大肠埃希氏菌和肺炎克雷伯氏菌的体外活性比较
Michael Kresken,Yvonne Pfeifer,Guido Werner
Michael Kresken
Carbapenems are considered the drugs of choice for first-line treatment of severe infections caused by carbapenem-susceptible, extended-spectrum β-lactamases (ESBL)-producing Enterobacterales, while piperacillin-tazobactam has been recomme...
Urinary tract infections in patients with renal insufficiency and dialysis - epidemiology, pathogenesis, clinical symptoms, diagnosis and treatment [0.03%]
肾功能不全和透析患者的泌尿系感染的流行病学、发病机理、临床表现、诊断及治疗
Jürgen E Scherberich,Reinhard Fünfstück,Kurt G Naber
Jürgen E Scherberich
Epidemiological studies show an increasing number of patients worldwide suffering from chronic kidney diseases (CKD), which are associated with a risk for progression to end-stage kidney disease (ESKD). CKD patients stage 2-5, patients with...
Retrospective audit of antibiotic use in a university general pediatrics department using hospital pharmacy dispensing data [0.03%]
基于医院药房发药数据的儿科抗菌药物使用回顾性审计研究
Leonie Egle,Katharina Sauter,Svenja Ockfen et al.
Leonie Egle et al.
Antibiotics are among the most frequently prescribed drugs in children's hospitals, which is why regular monitoring of antibiotic use in hospitals is of great importance. This retrospective audit (60 months, January 2014 - December 2018) an...