Molecular docking and dynamics studies of curcumin with COVID-19 proteins [0.03%]
姜黄素与新型冠状病毒蛋白的分子对接和动力学研究
Renuka Suravajhala,Abhinav Parashar,Gourav Choudhir et al.
Renuka Suravajhala et al.
Coronavirus disease 2019 (COVID-19) is caused by a Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-CoV-2), which is a positive-strand RNA virus. The SARS-CoV-2 genome and its association to SAR-CoV-1 vary from ca. 66 to 96% depending ...
A hybrid feature selection model based on improved squirrel search algorithm and rank aggregation using fuzzy techniques for biomedical data classification [0.03%]
基于改进的松鼠搜索算法和模糊技术等级聚合的混合特征选择模型用于生物医学数据分类
Gayathri Nagarajan,L D Dhinesh Babu
Gayathri Nagarajan
Feature selection has gained its importance due to the voluminous nature of the data. Owing to the computational complexity of wrapper approaches, the poor performance of filtering techniques, and the classifier dependency of embedded appro...
In-silico designing of epitope-based vaccine against the seven banded grouper nervous necrosis virus affecting fish species [0.03%]
基于抗原表位的七带真骨鱼神经坏死病毒疫苗的计算机设计
Amit Joshi,Dinesh Chandra Pathak,M Amin-Ul Mannan et al.
Amit Joshi et al.
Neural necrosis virus (NNV) of family Nodaviridae affect wide range of fish species with viral encephalopathy and retinopathy causing mass mortality up to 100%. Currently there is no effective treatment and depopulation is only suggested re...
Benchmarking mass spectrometry based proteomics algorithms using a simulated database [0.03%]
使用模拟数据库对基于质谱的蛋白质组学算法进行基准测试
Muaaz Gul Awan,Abdullah Gul Awan,Fahad Saeed
Muaaz Gul Awan
Protein sequencing algorithms process data from a variety of instruments that has been generated under diverse experimental conditions. Currently there is no way to predict the accuracy of an algorithm for a given data set. Most of the publ...
Inhibitory effect of anti-HIV compounds extracted from Indian medicinal plants to retard the replication and transcription process of SARS-CoV-2: an insight from molecular docking and MD-simulation studies [0.03%]
从分子对接和MD模拟研究中获得的印度草药化合物抗HIV抑制剂对SARS-CoV-2复制和转录过程的影响研究
Tanmoy Dutta,Nabajyoti Baildya,Abdul Ashik Khan et al.
Tanmoy Dutta et al.
Outbreak of Coronavirus (SARS-CoV-2) has thrown a big challenge to the globe by snatching millions of human lives from the world. In this study, inhibitory efficiency of ten anti-HIV compounds from different Indian medicinal plant parts hav...
Binding ability of arginine, citrulline, N-acetyl citrulline and thiocitrulline with SARS COV-2 main protease using molecular docking studies [0.03%]
精胺、瓜氨酸、N-乙酰基瓜氨酸和硫瓜氨酸与SARS-CoV-2主要蛋白酶结合能力的分子对接研究
Ramesh Thimmasandra Narayan
Ramesh Thimmasandra Narayan
In this article, the binding abilities of arginine, citrulline, N-acetyl citrulline and thiocitrulline on the active sites of SARS-COV-2 protease have been investigated using in-silico studies. All the above ligands bind selectively and pre...
Telehealth and the digital divide as a social determinant of health during the COVID-19 pandemic [0.03%]
新冠肺炎疫情期间的远程医疗与数字鸿沟——社会健康决定因素之一
Camille A Clare
Camille A Clare
Telehealth has been shown to have comparable health outcomes in terms of patient-physician communication, and patient satisfaction and engagement. Nevertheless, the digital divide has exacerbated the social and economic factors that create ...
In silico studies of selected multi-drug targeting against 3CLpro and nsp12 RNA-dependent RNA-polymerase proteins of SARS-CoV-2 and SARS-CoV [0.03%]
针对SARS-CoV-2和SARS-CoV的3CLpro和nsp12RNA依赖性RNA聚合酶蛋白的多药靶向的计算机模拟研究
Inemesit A Udofia,Kofoworola O Gbayo,Oluwakemi A Oloba-Whenu et al.
Inemesit A Udofia et al.
An outbreak of a cluster of viral pneumonia cases, subsequently identified as coronavirus disease 2019 (COVID-19), due to a novel SARS-CoV-2 necessitates an urgent need for a vaccine to prevent infection or an approved medication for a cure...
A mathematical model of COVID-19 transmission between frontliners and the general public [0.03%]
冠状病毒在前线和普通人群之间的传播数学模型
Christian Alvin H Buhat,Monica C Torres,Yancee H Olave et al.
Christian Alvin H Buhat et al.
The number of COVID-19 cases is continuously increasing in different countries including the Philippines. It is estimated that the basic reproduction number of COVID-19 is around 1.5-4 (as of May 2020). The basic reproduction number charact...
Estimation of drug-likeness properties of GC-MS separated bioactive compounds in rare medicinal Pleione maculata using molecular docking technique and SwissADME in silico tools [0.03%]
基于分子对接技术和SwissADME在线工具估算珍稀药用植物万代兰活性成分的药物 likeness性质
Hakani D Sympli
Hakani D Sympli
The main aim of the paper was to determine bioactive compounds in Pleione maculata extracts using gas chromatographic technique and to investigate their drug-likeness potential using molecular docking algorithm and ADME studies on the recen...