Antimalarial Natural Products [0.03%]
抗疟天然药物
David G I Kingston,Maria Belen Cassera
David G I Kingston
Natural products have made a crucial and unique contribution to human health, and this is especially true in the case of malaria, where the natural products quinine and artemisinin and their derivatives and analogues, have saved millions of...
Nguyen Thi Thuy Linh,Ninh The Son
Nguyen Thi Thuy Linh
The combination of traditional knowledge of medicinal plants with scientific rationale has yielded positive results in recent years. Bioactive compounds isolated from herbaceous plants have long been used as drugs that benefit human health,...
Nguyen Thi Thuy Linh,Ninh The Son,Nguyen Thi Thu Ha et al.
Nguyen Thi Thuy Linh et al.
Herbaceous annual plants of the genus Xanthium are widely distributed throughout the world and have been employed medicinally for millennia. This contribution aims to provide a systematic overview of the diverse structural classes of Xanthi...
A Timeline of Perezone, the First Isolated Secondary Metabolite in the New World, Covering the Period from 1852 to 2020 [0.03%]
佩雷ZONE的时间线，这是新世界中首次分离的二级代谢物，涵盖了从1852年到2020年的这段时期
René Escobedo-González,Pablo Mendoza,María Inés Nicolás-Vázquez et al.
René Escobedo-González et al.
This chapter covers a sesquiterpene quinone, commonly named perezone. This molecule is documented as the first secondary metabolite isolated in crystalline form in the New World in 1852. An introduction, with its structure, the IUPAC nomenc...
The Chemistry and Chemical Ecology of Lepidopterans as Investigated in Brazil [0.03%]
在巴西研究的鳞翅目昆虫的化学和化学生态学
Karina L Silva-Brandão,André V L Freitas,Márcio Zikán Cardoso et al.
Karina L Silva-Brandão et al.
The interdisciplinary field of Chemical Ecology in Brazil is currently composed of groups that emerged through the pioneering studies of Keith Spalding Brown Jr. and José Tércio Barbosa Ferreira. Following Keith Brown 's steps, José Robe...
Maggie M Reddy,Laurence Jennings,Olivier P Thomas
Maggie M Reddy
The term "marine biodiscovery" has been recently been adopted to describe the area of marine natural products dedicated to the search of new drugs. Several maritime countries such as Australia, New Zealand, South Korea, and Japan as well as...
Correction to: Antileishmanial Activity of Lignans, Neolignans, and Other Plant Phenols [0.03%]
Correction to：染料木素、新生理活性酚等的抗利什曼病活性
Jiří Pospíšil,Daniela Konrádová,Miroslav Strnad
Jiří Pospíšil
Steven D Shnyder,Colin W Wright
Steven D Shnyder
Cryptolepine, the principal constituent of the West African climbing shrub Cryptolepis sanguinolenta, continues to be of interest as a lead to new therapeutic agents, especially for the treatment of protozoal infections and cancer. This con...
Antileishmanial Activity of Lignans, Neolignans, and Other Plant Phenols [0.03%]
植物酚的抗利什曼病活性：木脂素、 neo-木脂素及其他植物酚类
Jiří Pospíšil,Daniela Konrádová,Miroslav Strnad
Jiří Pospíšil
Secondary metabolites (SM) from organisms have served medicinal chemists over the past two centuries as an almost inexhaustible pool of new drugs, drug-like skeletons, and chemical probes that have been used in the "hunt" for new biological...
From Plant to Patient: Thapsigargin, a Tool for Understanding Natural Product Chemistry, Total Syntheses, Biosynthesis, Taxonomy, ATPases, Cell Death, and Drug Development [0.03%]
从植物到患者——噻巴苷：理解天然产物化学、全合成、生物合成、分类学、ATP酶、细胞死亡和药物开发的工具
Søren Brøgger Christensen,Henrik Toft Simonsen,Nikolai Engedal et al.
Søren Brøgger Christensen et al.
Thapsigargin, the first representative of the hexaoxygenated guaianolides, was isolated 40 years ago in order to understand the skin-irritant principles of the resin of the umbelliferous plant Thapsia garganica. The pronounced cytotoxicity ...