Early aggressive treatment with DMARDs vs. step-up therapy in rheumatoid arthritis: a traditional review of joint damage and functional outcomes [0.03%]
早期积极使用改善病情的抗风湿药治疗类风湿关节炎与逐步升级治疗方案相比：关于关节损伤和功能结局的传统综述
Amruth Akhil Alluri,Aditya Rajesh Pawar,Shrishti Prakash Khetan et al.
Amruth Akhil Alluri et al.
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by progressive joint inflammation and structural damage. Two primary treatment strategies - step-up therapy and early aggressive DMARD therapy have been widely debated ...
Efficacy of flower pollen extract with vitamins in improving urinary and sexual function in patients with chronic prostatitis: a retrospective study [0.03%]
花粉提取物联合维生素改善慢性前列腺炎患者尿动力学和性功能的疗效：回顾性研究
Carlo Giulioni,Valentina Maurizi,Federico Falsetti et al.
Carlo Giulioni et al.
Objectives: To assess the efficacy and safety of Flower Pollen Extract with Vitamins (PEV) in improving urinary and sexual function in men diagnosed with chronic prostatitis (CP). ...
A retrospective observational study to evaluate the association between self-reported binge alcohol drinkers and asthma [0.03%]
一项回顾性观察研究：评估自我报告的放纵饮酒与哮喘之间的关联
Yashaswi Guntupalli,Bharath Sai Vejandla,Shruti Suresh Suvarna et al.
Yashaswi Guntupalli et al.
Objectives: To assess the association between binge drinking and asthma risk across demographic and socioeconomic groups. Methods: A re...
A prospective study to assess the prognosis of patients with necrotizing fasciitis using laboratory risk indicator for necrotizing fasciitis (LRINEC) scoring system in a tertiary care hospital [0.03%]
利奈辛评分系统对三级医院坏死性筋膜炎患者预后的预测价值：一项前瞻性研究
Rekha Walwekar,Vignesh Ramalingam,Arun Walwekar
Rekha Walwekar
Introduction: Necrotizing fasciitis (NF) is a rare but potentially fatal infection, involving the subcutaneous tissue and fascia. The incidence of NF worldwide ranges from 0.30 to 15 cases per 100,000 populations and mort...
Efficacy and safety of Mirikizumab in the treatment of moderate to severe active ulcerative colitis: a systematic review [0.03%]
米奎利珠治疗中重度活动性溃疡性结肠炎疗效和安全性的系统评价
Ajay Kumar Shukla,Saurav Misra,Ravi Kant Narayan et al.
Ajay Kumar Shukla et al.
Introduction: Ulcerative colitis in the second or third decade is characterised by haematochezia, stomach pain, faecal urgency, and tenesmus. On October 26, 2023, the US-FDA approved Mirikizumab for the treatment of moder...
An overview and comparison of haemovigilance reporting forms across six countries relative to the WHO template [0.03%]
六国血液安全监测报告表格设计与世界卫生组织模板的比较
Manmeet Kaur,Saurav Misra,Jayant Kumar Kairi
Manmeet Kaur
Objectives: Haemovigilance monitors, identifies, reports, investigates, and analyses adverse event near-misses and reactions related to transfusion and blood product manufacture. ...
Interleukin-23 (IL-23) inhibitor, mirikizumab in the treatment of ulcerative colitis (UC): a promising therapy? [0.03%]
interleukin-23（IL-23）抑制剂mirikizumab治疗溃疡性结肠炎（UC），会是一个新的希望吗？
Saurav Misra,Manmeet Kaur,Ashish Kumar Saranjhna
Saurav Misra
Mirikizumab is a monoclonal antibody that targets the human IL-23p19 and has been humanized with IgG4. It is currently under development for treating Crohn's disease and ulcerative colitis. The FDA approved mirikizumab on October 26, 2023 a...
The role of the urinary microbiome in diabetes-associated UTIs: current understanding and future directions [0.03%]
糖尿病相关尿路感染的泌尿道微生物组的作用：当前理解与未来方向
Meenakshi Reddy Yathindra,Rithvika Badugu,Shaurya Kumar Singh et al.
Meenakshi Reddy Yathindra et al.
This review explores the interplay between type 2 diabetes mellitus (T2DM) and urinary microbiome dysbiosis, focusing on its role in urinary tract infections (UTIs). Once considered sterile, the urinary tract hosts a diverse microbiota that...
Thyroid hormone imbalance, malnutrition, and sarcopenia: a triad of muscle health challenges [0.03%]
甲状腺激素失衡、营养不良和肌肉减少症：肌肉健康的三大挑战
Annarita Nappi,Serena Sagliocchi,Annunziata Gaetana Cicatiello et al.
Annarita Nappi et al.
Sarcopenia and malnutrition are increasingly recognized as major determinants of morbidity and functional decline in aging and chronically ill populations. Thyroid hormones (THs), particularly triiodothyronine (T3), play a critical role in ...
Menopause, estrogen, and GERD: an exploration of symptoms and endoscopic correlations [0.03%]
绝经、雌激素与胃食管反流病：症状及内镜表现的探讨
Praveena Meyyazhagan,Pavitra Vyshnavi Yogisparan,Thendral Anandaraj
Praveena Meyyazhagan
Objectives: To define the pattern of symptoms and severity of GERD among premenopausal and postmenopausal women in relation to estrogen levels and endoscopy findings. ...