Ascorbic acid attenuates lead-induced oxidative stress and testosterone suppression in male Wistar rats [0.03%]
维生素C对雄性威斯特大鼠铅诱导的氧化应激和睾丸酮抑制的缓解作用
Ifeanyi Gideon Aja,Mario Adesanya Adelaja,Olawale Olusoga Olubi et al.
Ifeanyi Gideon Aja et al.
Objectives: Lead (Pb) exposure is a major environmental risk factor for male reproductive dysfunction, primarily mediated through oxidative stress and endocrine disruption. This study evaluated the effects of lead acetate...
Altered semen fluid dynamics in smokers: a study on delayed liquefaction and increased viscosity [0.03%]
吸烟者精液液化延迟及粘度增加的力学原因研究
Praveena Meyyazhagan,Sanjeev Kumar Sundararaju,Priyadharshini Valluvan et al.
Praveena Meyyazhagan et al.
Objectives: Male reproductive health is vital for societal stability, and lifestyle-related factors significantly influence fertility. Tobacco smoking is a major modifiable risk factor implicated in male infertility. This...
Evaluation the reno-protective effect of tadalafil alone and in combination with ascorbic acid in AKI model in rats [0.03%]
评估西地那非及其与维生素C联合应用对AKI大鼠肾脏保护作用的效果
Tabarek Mohamed Salih,Majid Bashara
Tabarek Mohamed Salih
Background: Acute kidney injury (AKI) is associated with increased morbidity, prolonged hospitalization, and mortality, particularly in high-risk patients. ...
Achalasia today and tomorrow: surgery between robotic precision, functional phenotyping, and data-driven medicine [0.03%]
今天的食管失弛缓症与明天的食管失驰缓症：手术中的精准机器人技术、功能表型和数据驱动医学
Agostino Fernicola,Alfonso Santangelo,Luigi Ricciardelli et al.
Agostino Fernicola et al.
Effect of diuretics, angiotensin receptor blockers and beta-blockers on the quality of life among heart failure patients in a tertiary care hospital in North India [0.03%]
利尿剂、血管紧张素受体阻滞剂和β受体阻滞剂对北印度三级医疗机构心力衰竭患者生活质量的影响
Moksha Gupta,Neha Rani,Savita Devi et al.
Moksha Gupta et al.
Objectives: Patients with chronic heart failure (CHF) often experience poor quality of life as a result of difficulties in performing daily activities and impaired psychological health. This study aims to assess the assoc...
Novel SGLT2 inhibitors with endothelial-protective potential: a combined computational and experimental approach [0.03%]
一种具有保护内皮功能潜力的新型SGLT2抑制剂：计算与实验相结合的方法
Jarritt Romanik,Nina Gardella,Gabriela Dematteo et al.
Jarritt Romanik et al.
Objectives: Sodium-glucose co-transporter 2 (SGLT2) inhibitors are a class of anti-diabetic drugs with cardiovascular benefits independent of glycemic control, partly via endothelial protection. Identifying novel inhibito...
Comparative oncology of male and female breast cancer: diagnostic paradigms and machine learning approaches in treatment [0.03%]
男性和女性乳腺癌的比较肿瘤学：诊断范式和治疗的机器学习方法
Joy Das,Utpal Bhui,Gouri Shankar Chakraborty et al.
Joy Das et al.
Breast cancer is associated mostly with women; however, breast cancer also appears in men, which dictates the need to know about gender-specific differences in the pathology and treatment. Male breast cancer constitutes less than 1 % of all...
Trends in drug-induced liver injury (DILI): a case report-based analysis of clinical presentation, severity, preventability, seriousness, and outcomes over the last decade [0.03%]
基于病例报告的药物性肝损伤(DILI)十年变迁分析:临床表现、严重程度、可预防性、严重性和结局
Saurav Misra,Jayant Kumar Kairi,Manmeet Kaur et al.
Saurav Misra et al.
Background: DILI causes about 50 % of acute liver failures globally, affecting 14-19 per 100,000 annually, and is a leading cause of liver failure and drug withdrawals in the USA and Europe. ...
Hypoxia-induced cisplatin resistance in cancer: a comprehensive exploration of molecular mechanisms and novel therapeutic strategies [0.03%]
缺氧诱导的癌细胞顺铂耐药性：分子机制及新型治疗策略的全面探索
Malchi Suresh,Sakthivel Manju Bargavi,Kodiganti Naresh Kumar et al.
Malchi Suresh et al.
Tumor hypoxia is a critical contributor to cisplatin resistance, promoting molecular adaptations such as HIF-1α activation, reduced DNA repair capacity, metabolic reprogramming, and exosome-mediated drug efflux that collectively weaken cis...
Management of osteoarthritis using integrated approach: a meta-analysis [0.03%]
整合方法治疗骨关节炎的疗效评价：一项荟萃分析研究
Faizal E Kottikollon,Ravi S Parihar
Faizal E Kottikollon
Objectives: Osteoarthritis (OA) is a degenerative joint disease affecting millions worldwide, causing disability, reduced quality of life, and significant economic burden. Current clinical practices often fail to provide ...