Anti-inflammatory and antinociceptive activities of the aqueous leaf extract of Phyllanthus amarus Schum (Euphorbiaceae) in some laboratory animals [0.03%]
PhyllanthusamarusSchum(Euphorbiaceae)叶提取物的抗炎及镇痛作用研究
Adeolu A Adedapo,Sunday O Ofuegbe
Adeolu A Adedapo
Background: Phyllanthus amarus has a history of use in Ayurvedic medicine for over 2000 years as well as a wide variety of traditional applications and has gained popularity in many continents as a herbal remedy; hence, i...
Effect of (4a) a novel 5-HT3 receptor antagonist on chronic unpredictable mild stress induced depressive-like behavior in mice: an approach using behavioral tests battery [0.03%]
新型5-ht3受体拮抗剂(a)(4a)对慢性轻度不可预测应激抑郁模型小鼠行为学的影响研究
Yeshwant Kurhe,Radhakrishnan Mahesh,Deepali Gupta et al.
Yeshwant Kurhe et al.
Background: The inconsistent therapeutic outcome necessitates designing and identifying novel therapeutic interventions for depression. Hence, the present study deals with the investigation of antidepressant-like effects ...
The methanol-soluble fraction of Millettia macrophylla (Fabaceae) stem bark endowed with estrogenic properties has adverse effects on the male reproductive system of Wistar rats [0.03%]
大翼豆茎皮的甲醇可溶部分具有雌激素特性并对Wistar大鼠雄性生殖系统产生不利影响
Stéphane Zingue,Chantal Beatrice Magne Nde,Dieudonné Njamen
Stéphane Zingue
Background: The use of traditional medicinal plants to treat various diseases is common in Sub-Saharan African countries, including Cameroon. Millettia macrophylla, one of such plants, was previously found to exhibit estr...
A comparative study to evaluate the cardiovascular risk of selective and nonselective cyclooxygenase inhibitors (COX-Is) in arthritic patients [0.03%]
选择性与非选择性环氧化酶抑制剂的动脉粥样硬化风险：系统评价和 meta 分析
Uma A Bhosale,Nilofar Quraishi,Radha Yegnanarayan et al.
Uma A Bhosale et al.
Background: During the past 2 years, a great deal of evaluation has been accomplished on the cardiovascular (CV) effects of nonsteroidal anti-inflammatory drugs (NSAIDs), nonselective and selective cyclooxygenase-2 inhibi...
Kolaviron, a biflavonoid fraction from Garcinia kola, protects against isoproterenol-induced injury by mitigating cardiac dysfunction and oxidative stress in rats [0.03%]
姜黄素类似物 kolaviron 对异丙肾上腺素诱导的心肌损伤的保护作用及其对大鼠心脏功能障碍和氧化应激的影响
Oluwatosin Adekunle Adaramoye,Semiu Olasoju Lawal
Oluwatosin Adekunle Adaramoye
Background: The aim of this study was to evaluate the cardioprotective effects of kolaviron (KV), a biflavonoid from Garcinia kola seeds, in rats intoxicated with isoproterenol chloride (ISO) while quercetin (QUE) served ...
Review on treatment of premenstrual syndrome: from conventional to alternative approach [0.03%]
经前期综合征的治疗进展：从传统到替代疗法
Rohit Kumar Verma,Dinesh Kumar Chellappan,Awanish Kumar Pandey
Rohit Kumar Verma
Abstract Premenstrual syndrome (PMS) is the most common problem associated with women's health. Most women take alternative therapies for the treatment of PMS along with conventional therapies. A literature search was conducted which invest...
Pharmacological evaluation of the analgesic and anxiolytic activities of Jobelyn® in mice [0.03%]
Jobelyn®的镇痛和抗焦虑药理学评价
Solomon Umukoro,Anthony T Eduviere,Rukayat Ogunbiyi et al.
Solomon Umukoro et al.
Abstract Background: This study presents the results of the pharmacological evaluation of the analgesic and anxiolytic potentials of Jobelyn®, a potent antioxidant African herbal formulation, in mice. The analgesic effect was assessed util...
Antidepressant, anxiolytic, and anticataleptic effects of aqueous leaf extract of Antiaris toxicaria Lesch. (Moraceae) in mice: possible mechanisms of actions [0.03%]
来自Lesch。抗抑郁，抗焦虑和抗僵直作用以及Antiaris toxicaria（ Moraceae）的可能作用机制叶片提取物的小鼠
Esther O Agbaje,Ismail O Ishola,Joel A Oniyire
Esther O Agbaje
Abstract Background: The leaves of Antiaris toxicaria Lesch. (Moraceae) are used by traditional medicine practitioners in southwest Nigeria in the management of epilepsy, wounds, and neurological disorders. Hence, this study was undertaken ...
Antonio Siniscalchi,Luca Gallelli,Giovanni Malferrari et al.
Antonio Siniscalchi et al.
Stroke represents the most frequent cause of permanent disability in adults worldwide. Cerebral ischemia triggers the pathological pathways of the ischemic cascade and causes irreversible neuronal injury in the ischemic core within minutes ...
PKC-δ isozyme gene silencing restores vascular function in diabetic rat [0.03%]
PKC-δ等位基因沉默可恢复糖尿病大鼠血管功能
Kateryna Klymenko,Tetiana Novokhatska,Igor Kizub et al.
Kateryna Klymenko et al.
Abstract Background: Endothelium and K+ channel functionality in smooth muscle cells (SMCs) regulates vascular function and is exposed to damage in diabetes. The regulatory enzyme protein kinase C (PKC) is known to play a key role in vascul...