Expression of heterologous heparan sulphate binding protein of Helicobacter pylori on the surface of Lactobacillus rhamnosus GG [0.03%]
乳酸乳球菌GG表面异源表达幽门螺杆菌的肝素硫酸盐结合蛋白
Ashok Kumar Yadav,Sudarshan Reddy Varikuti,Ashwani Kumar et al.
Ashok Kumar Yadav et al.
Helicobacter pylori (H. pylori) is one of most commonly found pathogen in the stomach. In spite of emergence of different treatment strategies, H. pylori infection remains difficult to treat. The bioengineered probiotic lactobacilli that co...
A comprehensive review on RNA interference-mediated targeting of interleukins and its potential therapeutic implications in colon cancer [0.03%]
RNA干扰介导的白细胞介素靶向作用及其在结肠癌中的潜在治疗意义的综合回顾
Sagari Sil,Janet Bertilla,S Rupachandra
Sagari Sil
Colon cancer is the world's fourth leading cause of death. It is cancer of the latter part of the large intestine, i.e. the colon. Chronic inflammation over a long period also leads to the development of cancer. Cancer in the colon region i...
Fusel oil reaction in pressurized water: characterization and antimicrobial activity [0.03%]
高压水中的杂醇油反应：特征及抗菌活性
Thainara Bovo Massa,Lúcio Cardozo-Filho,Camila da Silva
Thainara Bovo Massa
This work aimed to investigate the reaction of fusel oil (FO) with pressurized water in a continuous flow reactor, in order to verify the effect of operating conditions (temperature and alcohol to water ratio) on the formation of reaction p...
Apoptosis induction in leukemic cells by L-asparaginase preparation from Bacillus indicus: bench-scale production, purification and therapeutic application [0.03%]
印度地衣杆菌L-天冬酰胺酶的制备诱导白血病细胞凋亡：工艺放样，纯化及临床应用
Deepankar Sharma,Abha Mishra
Deepankar Sharma
With the emergence of multiple side effects on the usage of commercial L-asparaginase formulations, keen interest is provoked to investigate new sources of L-asparaginases that possess antileukemic properties with minimal side effects. The ...
Long-term post-storage reactivation of a nitrifying sludge in a sequential batch reactor: physiological and kinetic evaluation [0.03%]
分批式反应器中储存后长期重新激活硝化污泥的生理和动力学评估
Daniel Maturano-Carrera,Omar Oltehua-Lopez,Flor de María Cuervo-López et al.
Daniel Maturano-Carrera et al.
Production, preservation and recovery of sludge with stabilized nitrifying activity over long time can be difficult. Information on the ability of nitrifying sludge to regain its nitrifying activity after long-term storage is still scarce. ...
Comparative evaluation of natural neuroprotectives and their combinations on chronic immobilization stress-induced depression in experimental mice [0.03%]
对慢性固定束缚压力引起的小鼠抑郁模型中天然神经保护剂及其组合的比较评估
Ibrahim M Ibrahim,Mohammed Alsieni,Sami G Almalki et al.
Ibrahim M Ibrahim et al.
The present study evaluates the potential of neuroprotective phytochemicals-rutin (R), resveratrol (Res), 17β-estradiol (17β-E2), and their different combinations against chronic immobilization stress (CIS)-induced depression-like behavio...
Reducing the biosynthesis of condensed tannin in winged bean (Psophocarpus tetragonolobus (L.) DC.) by virus-induced gene silencing of anthocyanidin synthase (ANS) gene [0.03%]
通过沉默紫花蛋白同源基因(anthocyanidin synthase, ANS)来减少四棱豆中缩合单宁的生物合成
Vinayak Singh,Rayees Ahmad Lone,Verandra Kumar et al.
Vinayak Singh et al.
The Underutilized legume-winged bean (Psophocarpus tetragonolobus (L.) DC.) and its various parts are infested with condensed tannin (CT) or proanthocyanidin (PA). CT has anti-nutritional effect as it adversely affects the digestion of prot...
Andrographolide-based potential anti-inflammatory transcription inhibitors against nuclear factor NF-kappa-B p50 subunit (NF-κB p50): an integrated molecular and quantum mechanical approach [0.03%]
基于穿心莲内酯的抗炎转录抑制剂针对核因子NF-κB p50亚单位(NF-κB p50)：结合分子和量子力学方法的研究
Priyanka Jain,C Sudandiradoss
Priyanka Jain
The unregulated activation of nuclear factor-κB (NF-κB) is a critical event in the progression of various inflammatory diseases such as ulcerative colitis, asthma, rheumatoid arthritis, bacterial induced gastritis, etc. Hence, blocking th...
Suppression of TLR signaling by IRAK-1 and -4 dual inhibitor decreases TPF-resistance-induced pro-oncogenic effects in HNSCC [0.03%]
通过TLR信号的IRAK-1和-4双抑制因子抑制可以降低HNSCC中TPF抗性诱导的促癌效应
Humayara Khan,Sachchida Nand Pandey,Abhishek Mishra et al.
Humayara Khan et al.
Combination of docetaxel, cisplatin and 5-FU, known as TPF, is an FDA-approved treatment for head and neck squamous cell carcinoma (HNSCC). Acquired chemo-resistance to TPF, a primary reason for non-responsiveness to the treatment and relap...
Screening, synthesis optimization, and scaling-up of phytopathogen antifungals derived from natural hydroxycinnamic acids [0.03%]
源自天然羟基桂皮酸的植物病原抗真菌物质的筛选、合成优化及放大研究
Doddy Denise Ojeda-Hernández,Ana Daniela Vega-Rodríguez,Ali Asaff-Torres et al.
Doddy Denise Ojeda-Hernández et al.
A simple screening methodology was employed to correlate the structures of hydroxycinnamic acids (HCAs) and their esterified derivatives with their in vitro antifungal activity over Fusarium oxysporum f. sp. lycopersici. The antifungal acti...