Deciphering bacterial wilt resistance in eggplant: identification of elite lines, DNA marker validation and transcriptome profiling [0.03%]
解码茄子细菌性枯萎病抗性：精英品系鉴定、DNA分子标记验证及转录组测序分析
Kasireddy Sivasankarreddy,Amina Aftab,Jiji Joseph et al.
Kasireddy Sivasankarreddy et al.
Bacterial wilt caused by Ralstonia solanacearum severely affects global eggplant production and necessitates the identification of resistant, high-yielding genotypes with consumer-preferred traits. In this study, eighteen diverse eggplant a...
Bioreactor technologies for bacterial-based vaccine manufacturing and industrial scale-up: insights and future prospects [0.03%]
基于细菌的疫苗制造和工业放大的生物反应器技术：见解与未来前景
Parvaneh Esmaeilnejad-Ahranjani
Parvaneh Esmaeilnejad-Ahranjani
The production of bacterial-based vaccines depends fundamentally on advanced bioreactor technologies, which are continuously evolving to meet rising demands for efficiency, quality, and scalability. In this review, several key challenges th...
Proteomics analysis of Pseudomonas plecoglossicida under thermal stress: the Entner-Doudoroff pathway as a temperature-dependent metabolic switch for thermal adaptation [0.03%]
热应激下假单胞菌(Pseudomonas)plecoglossicida蛋白质组分析：ED途径作为温度依赖型代谢开关参与热适应调节
Da-Ming Wang,Yu-Ming Jing,Qing-Hong Wang et al.
Da-Ming Wang et al.
Pseudomonas plecoglossicida is an industrial strain for the production of 2-keto-D-gluconic acid (2-KGA); however, its fermentation performance and 2-KGA yield significantly decline under high-temperature conditions. Tandem mass tag (TMT)-b...
Ameliorated potential and possible mechanisms of medicine food homology for depression [0.03%]
药食同源改善抑郁症的潜力及可能机制研究进展
Chunyan Huo,Qiang Li,Ning Cai et al.
Chunyan Huo et al.
Depression is a prevalent neuropsychiatric disorder that poses a significant global health burden. However, current pharmacotherapies are limited by adverse effects and substantial interindividual variability in efficacy. Medicine food homo...
Exploring Scolymus hispanicus L. leaves as a source of natural therapeutics: nutritional, phytochemical, and pharmacological evaluations [0.03%]
西班牙蔊菜叶子作为天然治疗资源的研究：营养、植物化学和药理学评估
Faleh Z Alqahtany,Abdelaaty Hamed,Mahmoud A Abdelaziz et al.
Faleh Z Alqahtany et al.
Scolymus hispanicus L. is an edible medicinal plant known for its richness in bioactive phytochemicals and its potential health-promoting properties. The present study aimed to investigate the phytochemical composition and evaluate the anti...
Unveiling the role of glycoproteins in hepatocellular carcinoma: from biomarkers to therapeutic interventions [0.03%]
肝细胞癌中糖蛋白的作用机制：从生物标志物到治疗干预措施
Aqsa Nadeem,Bhuvanesh Baskar,Sangeetha Gupta
Aqsa Nadeem
Hepatocellular carcinoma (HCC), which is mostly caused by chronic liver illnesses such as cirrhosis, non-alcoholic steatohepatitis, and viral hepatitis, continues to be one of the major causes of cancer-related death globally. Serum alpha-f...
Exploring salt-stress adaptation: genome-wide identification and expression profiling of the NHX (Na+/H+ antiporter) gene family in barley [0.03%]
盐胁迫适应机制研究：泛基因组鉴定和表达分析大麦NHX（Na+/H+反向转运蛋白）基因家族成员
Fatmah Ahmed Safhi,Samar G Thabet
Fatmah Ahmed Safhi
Salt stress poses a significant challenge to crop productivity, making it essential to understand the genetic mechanisms underlying salt tolerance in barley (Hordeum vulgare). In this study, we performed a comprehensive analysis of the barl...
Acute exercise shifts inferred immune cell composition and cytotoxic gene programs in pediatric sickle cell anemia [0.03%]
急性运动可改变儿童镰状细胞病推断的免疫细胞组成和细胞毒性基因程序
Jiajia Zhao,Haonan Shang,Zeting Fu et al.
Jiajia Zhao et al.
This study characterizes the acute exercise-induced remodeling of the whole-blood transcriptome and inferred immune microenvironment in pediatric and adolescent patients with sickle cell anemia (SCA). By integrating transcriptomic profiling...
Laccase as a green biocatalyst for xenobiotic degradation: integrative insights from molecular docking and bibliometric analysis [0.03%]
基于分子对接和文献计量分析的漆酶降解 xenobiotics 研究：绿色生物催化剂视角
Shivangi Chamoli,Ananta Gupta,Ashutosh Pal et al.
Shivangi Chamoli et al.
The current review critically discusses microbial laccase as an emerging green biocatalyst towards the sustainable degradation of xenobiotic pollutants. The review integrates current knowledge on laccase diversity, catalytic mechanisms, med...
Machine learning approaches to identify genetic markers for goat climatic adaptation [0.03%]
机器学习方法识别山羊气候适应遗传标志物
Chandana Sree Chinnareddyvari,C A Dharamshaw,S R Prashanthini et al.
Chandana Sree Chinnareddyvari et al.
Whole-genome SNP data from 109 goats, including 55 indigenous Indian goats and 54 exotic goats, were analyzed to identify ancestry informative markers (AIMs) associated with climatic adaptation. After quality filtering, 41,254,122 SNPs were...