Advances in hairy root technology: from pathway elucidation and omics integration for the scale-up production of biomolecules [0.03%]
毛状根技术的进步：从途径阐释及组学整合助力生物分子的大规模生产
Saikat Sena,Ajit Prakash,Vijay Kumar
Saikat Sena
Medicinal plants produce essential secondary metabolites which have immense potential in human welfare, including pharmaceutical and nutraceutical applications. Over the last few decades, hairy root cultures have emerged as a promising biot...
Genome sequence of multidrug-resistant Salmonella enterica serovar choleraesuis strain GS-198 isolated from retail chicken meat in Mathura, India [0.03%]
印度数学拉从零售鸡肉中分离出的多重耐药伤寒沙门氏菌GS-198株基因组序列
Gunjan Sahu,Prachi Singh,Chayanika Das et al.
Gunjan Sahu et al.
We report the draft genome sequence of Salmonella enterica subsp. enterica serovar Choleraesuis strain GS-198, isolated from retail poultry meat in Mathura, Uttar Pradesh, India. The draft genome comprised 87 contigs with a total length of ...
Case Reports
3 Biotech. 2026 Jun;16(6):213. DOI:10.1007/s13205-026-04849-1 2026
Design, synthesis, and in-vitro evaluation of 2-(heteroarylthio)acetamido-1 H-benzo[ d]imidazole derivatives as PTP1B inhibitors for the treatment of type 2 diabetes [0.03%]
设计、合成及体外评价2-（杂芳基硫）乙酰氨基-1H-苯并咪唑衍生物作为PTP1B抑制剂以治疗二型糖尿病
Praveen Kumar,Benjamin Ayodipupo Babalola,Zihan Qu et al.
Praveen Kumar et al.
Type 2 diabetes, driven by insulin resistance and β-cell dysfunction, is treated with drugs (metformin, GLP-1RAs, SGLT2 inhibitors, insulin) that lower glucose but often cause weight gain or hypoglycemia without restoring insulin sensitivi...
Design, synthesis, anticancer, antioxidant and computational evaluation of curcumin-benzodiazepine derivatives [0.03%]
姜黄素-苯二氮卓衍生物的设计、合成、抗肿瘤、抗氧化及计算评估研究
Kantharaju Kamanna,Deepak Yaraguppi,Krishnappa B Badiger et al.
Kantharaju Kamanna et al.
This work reported synthesis of curcumin benzodiazepine derivatives using aryl diamine with curcumin in the presence of acetic acid under microwave irradiation (MWI). The synthesized compounds homogeneity was verified using various spectral...
Quantifying neuron-specific enolase on TiO2-goldurchin-modified electrodes for lung cancer diagnosis [0.03%]
基于TiO2-尿酸修饰电极定量检测神经元特异性烯醇酶以辅助肺癌诊断
Xueying Yang,Thangavel Lakshmipriya,Subash C B Gopinath et al.
Xueying Yang et al.
This research was developed a neuron specific enolase (NSE) biosensor on titanium oxide (TiO2) modified interdigitated microelectrodes (IDME). Biotin-streptavidin strategy was utilized to immobilize the aptamer on IDME. It was identified th...
Purification of laccase from thermophilic Bacillus licheniformis SO8 with three-phase partitioning, characterization, and usage in dye decolorization [0.03%]
来自耐热的地衣芽孢杆菌SO8的漆酶的三相分配纯化，性质及在脱色领域的应用
Semih Yıldırgan,Esra Aygün,Rahime Altintas et al.
Semih Yıldırgan et al.
Laccase is an environmentally friendly biocatalyst capable of oxidizing a wide range of organic compounds and has attracted considerable interest for industrial wastewater treatment applications. In this study, laccase from the thermophilic...
Bioinformatic and experimental analysis reveals ITGA5 as a driver of ovarian clear cell carcinoma progression and platinum resistance [0.03%]
生物信息学和实验分析揭示ITGA5是卵巢透明细胞癌进展和铂耐药的驱动因素
Zuolian Xie,Li Chen,Wei Chen et al.
Zuolian Xie et al.
Ovarian clear cell carcinoma (OCCC) is a clinically aggressive subtype of epithelial ovarian cancer with limited therapeutic options. Here, we present a comprehensive study integrating bioinformatic analysis, experimental validation, and pr...
Immobilization of endo-xylanase from Thermomyces lanuginosus PC7S1T for selective production of xylooligosaccharides from agricultural residues [0.03%]
热绒茧酒红曲霉内切木聚糖酶的固定化及其在农业废弃物中选择性制备木寡糖中的应用
Laura Camila Wagner Rodio,Maria Eduarda Carboniéri,Tatiane Sayuri Inagaki et al.
Laura Camila Wagner Rodio et al.
Xylooligosaccharides (XOS) were produced from xylan-rich agricultural residues using endo-xylanase from Thermomyces lanuginosus PC7S1T immobilized on magnetic chitosan beads. The immobilized enzyme showed high immobilization yield (90.7%), ...
Prevalence of bacterial virulence factors directing mycotic aneurysm and its inhibition using silver nanoparticles [0.03%]
指导真菌性动脉瘤的细菌毒力因素及其使用银纳米颗粒抑制的流行率
Mohammed Dhanish,Jamith Basha Abdul Wahid,Kamel Hessini et al.
Mohammed Dhanish et al.
The study investigates the roles of bacterial virulence factors in the development of mycotic aneurysms and explores the potential of silver nanoparticles (AgNPs) as a therapeutic intervention. Mycotic aneurysms are different from degenerat...
Screening and evaluation of novel yeasts for biosurfactant production from the palm oil mill effluent [0.03%]
从棕榈油厂废水中筛选和评价新型酵母菌生产生物表面活性剂性能
Mudasir A Dar,Sylvia Fathin Maliihah,Toga Pangihotan Napitupulu et al.
Mudasir A Dar et al.
The present study reports the isolation, screening and characterization of diverse yeast strains from different geographical regions for the valorization of waste palm oil mill effluent (POME) for biosurfactant production. A total of 192 ye...