Tissue-resident immune cells in asthma: drivers of inflammation, memory, and airway remodeling [0.03%]
哮喘中的组织驻留免疫细胞：炎症、记忆和气道重塑的驱动因素
Payal Singh
Payal Singh
The complex inflammatory condition associated with airflow obstruction and variable airway hyperresponsiveness (AHR) is a characteristics condition of asthma. Exposure of the lungs to different environmental triggers, such as allergens, pol...
Transcriptome analysis of cacao reveals differentially expressed genes associated with resistance to Phytophthora palmivora [0.03%]
转录组分析揭示与可可树抵抗 Phytophthora palmivora 相关的差异表达基因
Nur Kholilatul Izzah,Murukarthick Jayakodi,Sang-Choon Lee et al.
Nur Kholilatul Izzah et al.
Black pod disease, caused by Phytophthora palmivora, severely constrains cacao production, necessitating the identification of resistance-related genes. This study employed high-throughput RNA sequencing (RNA-seq) using the Illumina platfor...
Fecal functional metagenomics reveals increased gut Bacillota/Pseudomonadota (Firmicutes/Proteobacteria) ratio and altered bacterial CAZyme profile in human colorectal cancer [0.03%]
人结直肠癌患者肠道芽孢杆菌门/假单胞菌门（厚壁菌门/变形菌门）比例升高及细菌CAZymes谱系改变的粪便功能元基因组学研究
Asif Hameed,Sudeep D Ghate,Rajesh P Shastry
Asif Hameed
Gut microbial dysbiosis has been implicated in the onset and/or progression of colorectal cancer (CC). We recently identified the emergence of low-abundance bacterial taxa affiliated with the phylum Bacillota in the gut microbiome of CC pat...
Genome-wide identification and function analysis of protease inhibitors in Brassica napus [0.03%]
油菜蛋白酶抑制剂的全基因组鉴定及功能分析
Guopeng Miao,Juan Han
Guopeng Miao
Protease inhibitors (PIs) are important regulators of proteolysis and play key roles in plant stress adaptation. Here, we performed a comprehensive genome-wide identification and integrative analysis of PI genes in Brassica napus. A total o...
Herbal nanotechnology-based topical drug delivery systems for the treatment of atopic dermatitis [0.03%]
基于草药纳米技术的外用药物递送系统治疗特应性皮炎
Zoya Firdaus,Dinesh Kumar Sharma
Zoya Firdaus
Atopic dermatitis (AD) is a chronic inflammatory skin disorder that markedly affects the quality of life of patients and their families. Although conventional treatments such as corticosteroids and immunomodulators are effective in controll...
Hypoxia exacerbates mechanical disuse-induced muscle decline through structural, functional, and molecular reprogramming in mice [0.03%]
Rizwan Qaisar,Megna Srinivas,Firdos Ahmad et al.
Rizwan Qaisar et al.
Prolonged physical inactivity, such as that occurring during bed rest, causes rapid skeletal muscle atrophy and weakness and is commonly modeled in rodents using hindlimb unloading (HU). In clinical settings, however, unloading often coexis...
Metagenomic profiling of endophytic microbiomes associated with fruit pulp and seed kernels of different mango varieties reveals conservation of bacterial communities in seed kernels [0.03%]
内生微生物组的元基因组分析表明细菌群落在不同芒果品种果肉和种子中的保守性分布
Basavaprabhu L Patil,C Shanmugaraj,M Madhusudan
Basavaprabhu L Patil
Bacterial and fungal communities associated with mango pulp and seed kernels from eight Indian mango varieties were profiled using 16 S rRNA and ITS amplicon sequencing. Bacterial diversity was consistently higher in seed kernels (647 ± 23...
DOX, 5-FU, and cisplatin delivery using RT-COF-1 at neutral pH conditions-in vitro analysis against MCF-7 cell line & drug release profile study [0.03%]
Gagandeep Kaur,Pawan Kumar
Gagandeep Kaur
Cytotoxicity analysis of COFs poses a significant hurdle for drug delivery applications. The potential of RT-COF-1 as anticancer drug carrier was examined through tagging of DOX, 5-FU and Cisplatin. The research work focuses on drug release...
Case Reports
3 Biotech. 2026 Jun;16(6):235. DOI:10.1007/s13205-026-04813-z 2026
Sanggenol L attenuates inflammation and apoptosis via Nrf2/PI3K/Akt signaling in retinal ganglion cells: an in vitro and in silico study on OGD/R-induced retinal ischemia-reperfusion injury [0.03%]
桑根酮L通过Nrf2/PI3K/Akt信号通路减轻视网膜神经节细胞炎症和凋亡：体外和分子模拟研究氧化糖酵解/复氧诱导的视网膜缺血再灌注损伤
Bing Xu,Periyannan Velu,June Fan et al.
Bing Xu et al.
This study evaluates the protective effects of Sanggenol L (SL), a flavonoid from Morus alba root bark, against retinal ischemia/reperfusion injury (RI/RI)-induced retinal ganglion cell (RGC) damage in an oxygen and glucose deprivation/reox...
Antibacterial potential and metabolite profiling of an endophytic Alternaria sp. FA-56 isolated from Ficus auriculata, a wild edible plant of the Indo-Burma belt [0.03%]
从印缅地区一种野生可食用植物Ficus auriculata分离得到的内生Alternaria sp. FA-56抗菌潜力及代谢组学分析
Jwngma Basumatary,Kumananda Tayung
Jwngma Basumatary
The present study reports the isolation and preliminary characterization of an endophytic fungal strain (FA-56) obtained from healthy leaves of Ficus auriculata. The isolate was identified as Alternaria sp. based on morphological characteri...