Anticancer potential of exosome-like nanoparticles isolated from Acorus calamus in breast cancer [0.03%]
菖蒲分离的外泌体类纳米粒子在乳腺癌中的抗肿瘤潜力
Sunny Gupta,Shipra Gupta,Manju Singh et al.
Sunny Gupta et al.
Plant-derived exosome-like nanoparticles represent a novel class of plant-based therapeutics with potential anti-cancer applications. The present study aims to isolate, characterize, and evaluate the Acorus calamus-derived exosome-like nano...
Potent phytoregulators from Pyrenacantha volubilis targeting ERα: a promising natural alternative for breast cancer therapy [0.03%]
婆仔藤雌激素受体α激动剂活性成分的发现及作用机制研究
Maya Ammathil Manoharan,Senthilkumar Umapathy,Beutline Malgija
Maya Ammathil Manoharan
Selective estrogen receptor modulators (SERMs) play a vital role in ER + ve breast cancer therapy, but existing synthetic drugs have limitations. This study explores Pyrenacantha volubilis as a potential natural source for SERM using molecu...
Identification of AKTIP as a biomarker for fibrolamellar carcinoma using WGCNA and machine learning [0.03%]
利用WGCNA和机器学习鉴定AKTIP作为肝纤维板层癌生物标志物
Rui Wang,Bo Ren,Xijie Zhang et al.
Rui Wang et al.
Fibrolamellar carcinoma (FLC) is a rare form of liver carcinoma with limited diagnostic and therapeutic options. In this study, we utilized the GSE57727 and E-MTAB-1503 datasets, downloaded from GEO and ArrayExpress, respectively, to explor...
Harnessing the power of stem cell-derived exosomes: a rejuvenating therapeutic for skin and regenerative medicine [0.03%]
利用干细胞源外泌体的力量：皮肤和再生医学的抗衰老疗法
Gracy Seth,Siddharth Singh,Geetansh Sharma et al.
Gracy Seth et al.
Exosomes are small extracellular vesicles produced by most cell types and contain proteins, lipids, and nucleic acids (non-coding RNAs, mRNA, and DNA) that can be released by donor cells to influence the function of recipient cells. Skin ph...
In-silico molecular investigation of Nannochloropsis microalgae cellulose synthase under salinity conditions and in-vitro evaluation of the proportionate effects on cellulose production [0.03%]
盐胁迫下纳米绿藻细胞壁果胶甲酯酶的分子功能及理化性质分析与体外催化性能评价
Seyed Mohammad Hasan Haghayeghi,Maryam Azimzadeh Irani,Hossein Askari et al.
Seyed Mohammad Hasan Haghayeghi et al.
Nannochloropsis is a microalgae with more than substantially 60-70% cellulose in its cell wall, making it a potential candidate for nanocellulose sustainable production. This study examined the effects of salts in seawater and their role on...
PacBio-based de novo transcriptomics of the coconut rhinoceros beetle Oryctes rhinoceros identifies physiologically important full-length genes and sheds insights into the molecular relationship (chitin synthase) between Scarabaeidae (Coleoptera) and Hymenoptera [0.03%]
基于PacBio从头转录组测序的独角犀甲虫(Oryctes rhinoceros)高质量全长基因预测及重要生理基因分析和白蚁(Hymenoptera)与粪金龟科(Coleoptera Scarabaeidae)信息素受体分子关系研究
Sreeramulu Bhuvaragavan,Kannan Sruthi,Ramanathan Nivetha et al.
Sreeramulu Bhuvaragavan et al.
The sparser molecular data in non-model insects such as Oryctes rhinoceros prompted us to investigate and identify its physiologically important genes using the novel PacBio Iso-Seq Sequel II platform with single-molecule real-time (SMRT) t...
Characterization of Fusarium oxysporum f. sp. lini based on ITS and SSR Markers and identification of resistance of Indian Linseed (Linum usitatissimum L.) to Fusarium oxysporum f. sp. lini [0.03%]
基于ITS和SSR标记的大豆疫霉分离物的鉴定及印度亚麻对Fusarium oxysporum f. sp. lini抗性的识别
Gopala,Beena Nair,J M Parbat et al.
Gopala et al.
Different isolates of Fusarium oxysporum f. sp. lini (Fol) collected from seven linseedgrowing states in India were analyzed for their cultural characteristics, pathogenicity, and genetic diversity using ITS and SSR markers. The isolates ex...
Helicobacter pylori CagA and CagT antibodies arrest the translocation of CagA into gastric epithelial cells [0.03%]
抗幽门螺旋杆菌CagA和CagT的抗体能够阻止CagA向胃上皮细胞内的转移
Swagata Sain,Bhawna Solanki,Navin Kumar
Swagata Sain
Cytotoxic-associated gene A (CagA) is a key virulence factor of Helicobacter pylori, associated with gastric ulcers and stomach cancer. The bacterium employs a Cag-type IV secretion system for translocation of CagA into the host cells. This...
Exploring microalgae-based strategies for the management of white spot syndrome virus: a comprehensive review [0.03%]
基于微藻的管理白斑综合症病毒策略的研究：全面综述
Amrutha Vellore Mohankumar,Vernita Priya,Sanjana Anbalagan et al.
Amrutha Vellore Mohankumar et al.
Shrimp culture industries faced huge economic losses due to white spot disease (WSD) caused by the white spot syndrome virus (WSSV). Microalgae are unicellular and can be found in both freshwater and marine habitats. In recent days, microal...
Integrated insight and in silico investigation of hybrid bis-thiazolidinone derivatives along with anti-Alzheimer activity [0.03%]
兼具抗阿尔茨海默活性的杂合双噻唑烷二酮衍生物的综合见解及计算机辅助研究
Shoaib Khan,Tayyiaba Iqbal,Mujaddad Ur Rehman et al.
Shoaib Khan et al.
In the current study, a novel route was established for the synthesis of hybrid benzothiazole derived thiazole bearing bis-thiazolidinone-chalcone (1-15) scaffolds. These compounds were screened for their biological potential as anti-Alzhei...