Mucoadhesive TMC-coated solid lipid nanoparticles for oral co-delivery of docetaxel and curcumin: formulation optimization, in vitro characterization, and cytotoxic evaluation [0.03%]
用于口服递送多西他赛和姜黄素的黏膜粘附TMC涂层固体脂质纳米粒:配方优化,体外表征及细胞毒性评价
Atefeh Yassemi,Soheila Kashanian,Mahsa Babaei et al.
Atefeh Yassemi et al.
Solid lipid nanoparticles (SLNs) coated with N-trimethyl chitosan (TMC) represent advanced strategy for oral drug delivery due to enhanced mucoadhesion and gastrointestinal stability. This study aimed to develop, characterize, and evaluate ...
Heterologous expression of a cold-active small esterolytic enzyme from Pseudomonas sivasensis R11S16 and its potential for azithromycin removal [0.03%]
来源于芽孢杆菌R11S16的低温下活性高的小分子酯酶的杂合表达及其去除阿奇霉素的潜力
Gizem Çon,Emre Karakaya,Hayrettin Saygin et al.
Gizem Çon et al.
The gene encoding a hypothetical YqiA/YcfP family α/β-fold hydrolase from Pseudomonas sivasensis R11S16 was cloned, heterologously expressed in Escherichia coli, and purified as a histidine-tagged recombinant enzyme (PsEstyfh). The enzyme...
Use of Serratia marcescens SK1 and Bacillus cereus SK1 as a natural biosorbent to remove cadmium, lead, nickel and zinc from foundry soil [0.03%]
用产红壤芽孢杆菌SK1和枯草芽孢杆菌SK1作为天然生物吸附剂去除铸造土壤中的镉、铅、镍和锌
Kasthuri Sivakumar,Pratheeba Sintharaj,Shanmuga Priya Ramasamy
Kasthuri Sivakumar
The present study evaluates the efficacy of two bacterial isolates, Serratia marcescens SK1 and Bacillus cereus SK1, in remediating cadmium, lead, nickel and zinc contaminated foundry soil S. marcescens SK1 exhibited Minimum Inhibitory Conc...
From intake to impact: dietary modulation of the gut-brain axis across health and neurological disease [0.03%]
从摄入到影响:饮食调节健康和神经疾病下的脑肠轴作用力
Jyoti Kumari,Shuvajit Das,Sneha Ranjan et al.
Jyoti Kumari et al.
The gut-brain axis (GBA) is an intricate, bidirectional communication network linking the gastrointestinal microbiota to the central nervous system. Mounting evidence underscores its critical role in the pathogenesis of neurological and neu...
Isolation and characterization of metal resistant plant growth promoting endophytic bacteria from Cynodon dactylon L. (Pers) [0.03%]
从结缕草中分离并表征耐金属的植物生长促进内生细菌
Aatika Shehzadi,Shazia Rehman,Sadia Malik et al.
Aatika Shehzadi et al.
Heavy metal contamination threatens soil health and ecosystem stability. Endophytic bacteria from metal-tolerant plants can enhance phytoremediation. In this study, twenty-four endophytic bacterial isolates were isolated from leaves and roo...
Omics-based insights into endophytic Bacillus subtilis (TN FL 158) for blister blight management in Camellia sinensis [0.03%]
基于组学的芽孢杆菌(TN FL 158)在山茶属植物 blister 病害管理中的研究进展
K Murugavel,G Karthikeyan,M Raveendran et al.
K Murugavel et al.
Blister blight of tea (Camellia sinensis), caused by Exobasidium vexans, is one of the most destructive foliar diseases in South India, with an incidence of up to 68% and yield losses approaching 50%. In the present study, an endophytic bac...
Bioprospecting Cycas revoluta-associated bacterial endophytes for tomato (Solanum lycopersicum L.) growth promotion under salt stress [0.03%]
从铁松内生菌中筛选促进盐胁迫下番茄生长的促生菌
Jalila Benjelloun,Mohamed Hnini,Sarah Bouzroud et al.
Jalila Benjelloun et al.
Twenty endophytic bacterial strains isolated from Cycas revoluta coralloid roots were characterized for their salt stress tolerance and phyto-beneficial properties, mainly indole-3-acetic acid production, siderophore secretion and phosphate...
Xylanase production by Streptomyces xantholiticus K7 using agro-industrial by-products: statistical optimization, biochemical characterization, and juice clarification potential [0.03%]
应用农业工业副产品进行链霉菌K7产木聚糖酶的统计优化、生化鉴定及其澄清果汁潜力的研究
Sara Ghozlane Attar,Maria Smati,Selvapravin Kumaran et al.
Sara Ghozlane Attar et al.
Streptomyces xantholiticus K7, isolated from an Algerian saline lake, achieved efficient xylanase production exclusively on agro-industrial by-products, without additional nutrient supplementation. Statistical optimization using a Central C...
SUMO3/ RUNX1/ AIRE/ RCAN1 and DNMT3L/ DYRK1A/ Let-7c-5p/ VEGF axes: immune dysregulation and genetic susceptibility as pulmonary risk factors in Down syndrome [0.03%]
Down综合征中的免疫调节异常和遗传易感性:SUMO3/RUNX1/AIRE/RCAN1和DNMT3L/DYRK1A/Let-7c-5p/VEGF轴作为肺部风险因素
Alaa Elmetwalli,Samaa Ahmed El-Sakka,Othman R Alzahrani et al.
Alaa Elmetwalli et al.
This study investigated the cytokine profiles and expression patterns of chromosome 21 genes in Saudi Arabian children with Down syndrome (DS) to identify molecular drivers of immune dysregulation and pulmonary complications. This case-cont...
Formulation and in vitro evaluation of nano-based ointments using L929 and THP-1 cell lines: a novel approach for wound-healing applications [0.03%]
基于纳米的药膏的配方和体外评价:用于伤口治疗的新方法
Reya Rene Philip,R Akshaya Priya,Jayashri Seetharaman et al.
Reya Rene Philip et al.
Healing for wounds remains a major clinical challenge, often requiring treatments that combine anti-inflammatory, antioxidant, and antimicrobial properties. This study presents a novel curcumin-functionalized copper nanoparticle ointment an...