Potentials of cepharanthine and tomatidine as novel LpxC and TLR4 inhibitors to mitigate gut-mediated inflammation in Parkinson's disease: a high-throughput investigation through molecular docking and dynamic simulation [0.03%]
Rubina Roy,Indira Gahatraj,Anupama Sharma et al.
Rubina Roy et al.
Gut dysbiosis is strongly implicated in the pathogenesis of Parkinson's disease (PD), where the interaction between bacterial endotoxin lipopolysaccharide (LPS) and human toll-like receptor 4 (TLR4) plays a crucial role. Inhibiting LPS-synt...
Unravelling the molecular landscape of Bhendi Yellow Vein Mosaic Virus (BYVMV) in bitter gourd: genetic characterization and structural insights [0.03%]
Bichhinna Maitri Rout,Amish Kumar Sureja,Manjusha Verma
Bichhinna Maitri Rout
During a field survey at the Indian Agricultural Research Institute, New Delhi, the bitter gourd (Momordica charantia L.) cv. Pusa Do Mausami showed prominent symptoms characterized by severe yellow mosaic and leaf curling. Through leaf-dip...
High-throughput sequencing analysis of community diversity and functional structure of endophytic bacteria in edible vegetable crops: potential implication on plant microbiological quality [0.03%]
Adekunle Raimi,Rasheed Adeleke
Adekunle Raimi
This study evaluated the diversity and functional structure of endophytic bacterial communities residing within four common leafy vegetables: Brassica oleracea, Lactuca sativa, Allium cepa, and Spinacia oleracea, cultivated under organic (O...
Breaking barriers: exploring blood-brain barrier crossing mechanisms with nanomedicine for effective glioma treatment [0.03%]
突破壁垒：利用纳米药物探索血脑屏障穿越机制有效治疗胶质瘤
Syed Hammad Ali,Hiba Ali,Midhat Shafi et al.
Syed Hammad Ali et al.
This review comprehensively highlights recent studies on the potential immunotherapy targets and nanomedicine strategies to enhance glioma treatment by overcoming the blood-brain barrier (BBB). Various nanoparticles, such as liposomes, poly...
Production of ethyl butyrate by a triple cascade process of the continuous submerged and solid state fermentation with corn stover [0.03%]
基于玉米秸秆的连续液态和固态发酵三级联产丁酸乙酯的过程
Dongsheng Xue,Jie Huang,Jueyan Chen et al.
Dongsheng Xue et al.
The gas lift bioreactor, the anaerobic fermentor and the anaerobic solid state fermentor were connected to continuously produce ethyl butyrate with corn stover as the substrate. The activities of the cellulase from the immobilized Aspergill...
Genome-wide identification of the apple NLP (NIN-like proteins) family and their potential role under abiotic stress [0.03%]
苹果NLP（NIN-like蛋白）家族的全基因组鉴定及其在非生物胁迫下的潜在作用
Junrong Li,Qiandong Hou,Xiangmei Nie et al.
Junrong Li et al.
NIN-like proteins (NLPs), unique to plants, are conserved transcription factors that significantly influence nitrate levels. However, a comprehensive analysis of the apple NLP gene family remains lacking. In this study, five NLP members wer...
Polar microalgae-based nanoparticles: a next-generation strategy for cancer treatment [0.03%]
基于极地微藻的纳米颗粒：癌症治疗的下一代策略
Gülcan Ayşin Karaca,Özgür Cem Erkin,Benan İnan et al.
Gülcan Ayşin Karaca et al.
Polar microalgae are one of the species that produce valuable bioactives and effective antioxidants as a metabolic adaptation mechanism to tolerate harsh conditions of polar regions. In this manner, evaluating bioactive compounds obtained f...
Anti-infective synergy of Acacia nilotica bioactive fraction and methyl gallate with meropenem against pathogenicity of Pseudomonas aeruginosa [0.03%]
甲壳素纳米颗粒介导的卡巴他赛抗肿瘤作用及机制研究
Samreen,Iqbal Ahmad
Samreen
A combination approach using phytocompounds with antibiotics offers a promising strategy to enhance antibiotic efficacy and reduce pathogen virulence. This study investigates the synergistic antibacterial and anti-virulence potential of Aca...
Holistic transition in the anaerobic digestion: influences of multiple process controls on the methane enrichment [0.03%]
厌氧消化的系统调控对产甲烷效能的影响研究
Vignesh Natarajan,G L Karthik
Vignesh Natarajan
Anaerobic digestion (AD) of organic wastes primarily generates biogas, an accessible bioenergy resource. The process is straightforward; however, complexity increases at elevated organic loading rates. For instance, the methane yield decrea...
Whole genome sequence analysis of a novel Streptomyces sp. BG6AG reveals its lipase production potential: optimization of the process through Taguchi experimental design [0.03%]
整个基因组序列分析揭示了新型链霉菌BG6AG的脂酶产生潜力：通过Taguchi实验设计优化生产过程
Zahra Parwez,Subhransu Sekhar Behera,Ananta Narayan Panda et al.
Zahra Parwez et al.
This study reports a lipase-producing Streptomyces strain BG6AG isolated from Chilika Lake, Odisha, India. Whole genome analysis revealed a genome size of 7,565,774 base pairs with a GC content of 72.2%. The genomic analysis identified 6740...