A β-TCP/PMMA composite bone cement promotes osteogenic differentiation of osteoporotic rBMSCs via Wnt/β-catenin pathway [0.03%]
一种新型β-TCP/PMMA骨水泥可通过Wnt/β-连锁蛋白信号通路促进骨质疏松环境下的间充质干细胞成骨分化
Rui Chun Wang,Yi Yang,Jia Hon Chen et al.
Rui Chun Wang et al.
Osteoporosis-induced bone defects represent a severe clinical challenge that requires high-performance bone repair biomaterials. To address the limited osteoinductivity, excessive curing heat, and poor degradability of conventional PMMA bon...
Targeted niosomes protect the heart from doxorubicin-induced injury: evidence from oxidative stress, pyroptosis, and apoptosis pathways [0.03%]
靶向尼奥索膜通过氧化应激、焦亡和凋亡途径保护多柔比星致心肌损伤
Singaravel Vijayapoopathi,Kalaiyarasi Kasirajan,Malathi Sampath et al.
Singaravel Vijayapoopathi et al.
Doxorubicin (DOX) is a frontline chemotherapeutic agent whose clinical utility is significantly limited by dose-dependent and often irreversible cardiotoxicity. Niosomal drug delivery systems, owing to their biocompatibility and tumour-targ...
Ferulic acid attenuates early life stress induced behavioral and neurochemical alterations via modulating HPA axis, oxidative stress, and NF-κB mediated neuroinflammation [0.03%]
阿魏酸通过调节HPA轴、氧化应激和NF-κB介导的神经炎症来缓解生命早期压力引起的.behavioral和神经化学改变
Simran,Varinder Singh,Navjot Kanwar et al.
Simran et al.
The present study investigated the protective effects of ferulic acid against behavioral and neurochemical alterations induced by early life stress (ELS) using a maternal separation model in mice. Swiss albino mouse pups were subjected to m...
Fabrication and characterization of biocompatible BPC-157 based chitosan hydrogel [0.03%]
一种生物相容性的BPC-157基葡聚糖水凝胶的制备及表征研究
Arunim,Monika Dagar,Misika Solanki et al.
Arunim et al.
Multifunctional hydrogels are essential for advanced biomedical applications. In this study, CH/BPC composite hydrogel was fabricated and characterized for their physicochemical properties. The formulation exhibited a porous structure, anal...
Production optimization of cellulase from Bacillus licheniformis and its application in paper pulp modification and biobleaching [0.03%]
芽孢杆菌产纤维素酶的发酵优化及其在造纸工业中的应用研究
Pooja Thakur,Kamal Kumar Bhardwaj,Savitri et al.
Pooja Thakur et al.
The demand for sustainable and eco-friendly processes in the paper industry has driven the exploration of efficient enzymatic systems. In this study, cellulase production from thermophilic Bacillus licheniformis (NCBI Accession No.: KR34046...
Bio-engineered CeO₂ nanoparticles: a sustainable approach for photocatalytic degradation of environmental pollutants [0.03%]
生物工程制备的CeO₂纳米粒子：环境污染物光催化降解的可持续方法
Asadullah,Iftikhar Ahmed,Calvyn Howells et al.
Asadullah et al.
Green synthesis of cerium oxide nanoparticles (CeO2 NPs) using plant-derived biomolecules has emerged as a sustainable alternative to conventional chemical synthesis methods. This review critically evaluates recent advances in plant-mediate...
Comparative genomic analysis of two virulent Metarhizium rileyi (Hypocreales: Clavicipitaceae) isolates reveals enhanced virulence potential [0.03%]
两个致病力较强的稻轮枝菌（轮枝孢目：麦角菌科）分离株的比较基因组分析揭示了增强的致病潜力
P Duraimurugan,D Neethu Roy,Divya Shree et al.
P Duraimurugan et al.
Two virulent Metarhizium rileyi isolates, SlMr-DOR and SfMr-DOR, were comparatively characterized using morphological, pathogenicity, molecular, phylogenetic, and whole-genome analyses to investigate genomic differences associated with thei...
A synergistic pomegranate-biopolymer bio-stimulant enhances barley growth, heat stress resilience, and antimicrobial activity through physiological and molecular modulation [0.03%]
一种协同的石榴-生物聚合物生物刺激素通过生理和分子调节增强大麦生长，热应力抗性和抗菌活性
Eman Tawfik,Zeinab Khalid,Nourhan Osama et al.
Eman Tawfik et al.
Global agricultural challenges necessitate sustainable strategies to enhance crop productivity and resilience under environmental stress. This study investigated the synergistic effects of a novel bio-stimulant formulation consisting of pom...
Modulation of glycation, inflammation, and detoxification pathways by D-Galactose through the RAGE-NF-κB-Nrf2 signaling axis in liver and kidney of Wistar rats [0.03%]
D-半乳糖通过Wistar大鼠肝脏和肾脏中的RAGE-NF-κB-Nrf2信号轴调节糖基化、炎症和解毒通路
Nilima S Bangar,Baishali Chakraborty,Rashmi S Tupe
Nilima S Bangar
D-galactose (D-Gal) is used to induce aging-associated pathological complications; however, its dose-dependent effects on RAGE-NF-κB and Nrf2 pathways remain unexplored. We examine the effects of D-Gal (400, 500, and 600 mg/kg body weight)...
Evaluation of antibacterial and antibiofilm activity of Lacticaseibacillus sp. KJK14S1 strain isolated from unexplored region of Indian Sundarbans against Gram-negative bacteria [0.03%]
从印度桑迪贝ens区域分离的乳酸威氏菌KJK14S1株对抗假单胞菌属细菌的抗菌和抗生物被膜活性评价
Ruchita Santra,Pankaj Paul,Sandip Dolui et al.
Ruchita Santra et al.
The ethyl acetate fraction of Lacticaseibacillus sp. KJK14S1 exhibited antibacterial activity against Gram-negative pathogens under the experimental conditions employed. Microbroth dilution assays showed that Klebsiella pneumoniae ATCC 7006...