Insulin resistance and cognitive decline: the metabolic mechanisms linking type 2 diabetes to Alzheimer's disease [0.03%]
胰岛素抵抗与认知功能下降：2型糖尿病与阿尔茨海默病之间代谢机制的关联
Haya Majid,Mansi Dahalia,Shadan Hussain et al.
Haya Majid et al.
Background: Alzheimer's disease (AD) and Type 2 Diabetes Mellitus (T2DM) share overlapping pathophysiological pathways, including metabolic reprogramming, oxidative stress, and impaired cellular homeostasis. ...
Glycated hair protein analysis as a noninvasive proxy for blood glucose monitoring: investigating the impact of sample mass and chemical hair treatments [0.03%]
糖化头发蛋白分析作为非侵入性血糖监测手段：探讨样品质量和化学发质处理的影响
Andrew S Dhanoo,Brian N Cockburn
Andrew S Dhanoo
Background: Cost-effective, noninvasive methods to assess glycemic control can aid Diabetes Mellitus (DM) screening and management. We assess the potential of glycated protein in scalp hair as a surrogate marker for glyce...
Consensus statement on novel glucose-related metrics obtained through advanced medical devices: English version [0.03%]
新型血糖指标国际共识（英文版）
Rimei Nishimura,Yosuke Okada,Akio Kuroda et al.
Rimei Nishimura et al.
Changes in eating behavior and diet-related quality of life in individuals treated with tirzepatide for type 2 diabetes [0.03%]
tirzepatide治疗2型糖尿病患者的饮食行为及生活质量的变化
Shiori Toga-Sato,Takahiro Tosaki,Yuichi Hodai et al.
Shiori Toga-Sato et al.
Aims: We investigated changes in eating behavior associated with the administration of tirzepatide and evaluated any changes in diet-related QOL due to tirzepatide. ...
Impact of concomitant use of antiplatelet agents on the production of anti-insulin antibodies in patients with type 2 diabetes treated with insulin analogues [0.03%]
抗血小板药物联用对胰岛素类似物治疗的2型糖尿病患者产生抗胰岛素抗体的影响
Tokio Sanke,Eri Tamagawa,Yuko Matsuoka et al.
Tokio Sanke et al.
Background: We have already reported that anti-insulin antibodies are produced at a fairly high frequency in type 2 diabetic patients treated with insulin analogues, and the amount of insulin requirement was significantly...
Differences in clinical characteristics between definite and probable slowly progressive insulin-dependent diabetes mellitus in real-world clinical settings in Japan (JDDM 79) [0.03%]
日本真实临床环境中成人迟发性1型糖尿病(DIPED)患者(JDDM 79研究):糖尿病确诊时临床特点的差异性分析
Keiko Arai,Mariko Oishi,Noriharu Yagi et al.
Keiko Arai et al.
Aims: The Japan Diabetes Society revised the diagnostic criteria for slowly progressive insulin-dependent diabetes mellitus (SPIDDM) in 2023. We aimed to clarify the clinical differences between definite and probable SPID...
Effect of tofogliflozin on obesity-related health problems in patients with type 2 diabetes and overweight or obesity-a post-hoc sub-analysis of the UTOPIA study [0.03%]
托格列净对2型糖尿病伴肥胖患者的影响——UTOPIA研究的事后亚组分析
Naoto Katakami,Tomoya Mita,Takafumi Masuda et al.
Naoto Katakami et al.
Objective: This study aimed to evaluate the effects of tofogliflozin, a sodium-glucose cotransporter 2 inhibitor, on health issues in patients with type 2 diabetes (T2DM) and overweight or obesity in real-world clinical p...
Role of metallothionein 3 in diabetic nephropathy via interplay with HIF-1α [0.03%]
金属硫蛋白3通过与HIF-1α相互作用在糖尿病肾病中的作用
Yuri Takiyama,Yumi Takiyama,Takao Takiyama et al.
Yuri Takiyama et al.
Metallothioneins (MTs) are a cysteine-rich protein that scavenges reactive oxygen species. Hypoxia is involved in the progression of diabetic nephropathy (DN) and aggravates oxidative stress. Hypoxia dramatically induced MT3, whereas induce...
Association of impaired awareness of hypoglycemia and real-time continuous glucose monitoring with the occurrence and frequency of severe hypoglycemia in adults with type 1 diabetes mellitus: a real-world panel data analysis from the PR-IAH study [0.03%]
1型糖尿病成人低血糖无觉察障碍与实时连续葡萄糖监测对严重低血糖发生及频率影响的现实世界面板数据分析：来自PR-IAH研究的发现
Naoki Sakane,Ken Kato,Sonyun Hata et al.
Naoki Sakane et al.
Background: Patients with long-standing type 1 diabetes mellitus (T1DM) often experience severe hypoglycemia (SH); however, the protective and risk factors that influence its occurrence and frequency in the era of advance...
Real-world use of finerenone in diabetic kidney disease: eGFR slope analysis with exploratory data on prior MRA use [0.03%]
芬戈利蒙特治疗糖尿病肾病的现实世界使用情况：eGFR斜率分析及以往使用MRAs情况的探索性数据分析
Yuka Yamao,Miwa Ota,Keizo Kanasaki
Yuka Yamao
In the post-SGLT2 inhibitor era, residual renal risk remains a major concern in diabetic kidney disease (DKD). Finerenone, a non-steroidal mineralocorticoid receptor antagonist (MRA), has shown cardiovascular and renal benefits in clinical ...