Time trends in the prescription of sodium-glucose co-transporter-2 inhibitors based on a claims database in Japan from 2014 to 2022: expanded use in older adults, those with comorbidities, and those potentially initiating diabetes treatment [0.03%]
基于日本2014年至2022年的索赔数据库钠-葡萄糖共转运蛋白-2抑制剂处方趋势：老年人、合并症患者和潜在糖尿病患者的用药扩展分析
Takuma Koinuma,Manato Yoshida,Manabu Akazawa
Takuma Koinuma
Background/objectives: Sodium-glucose cotransporter-2 inhibitors (SGLT2Is) were initially prescribed with caution due to potential adverse effects, including hypoglycemia, ketoacidosis, dehydration, and genital or urinary...
The association between diabetes knowledge, treatment satisfaction and medication adherence among Malaysian geriatric patients [0.03%]
马来西亚老年糖尿病患者糖尿病知识、治疗满意度和用药依从性之间的关系
Nur Syaqirah Natasha Mohamad Yusaini,Muhammad Eid Akkawi
Nur Syaqirah Natasha Mohamad Yusaini
Background: Medication adherence among geriatric diabetic patients is influenced by various factors, including diabetes knowledge and treatment satisfaction. Understanding these relationships is crucial for improving adhe...
Effects of a home-based low-to-moderate-intensity dance exercise program on glycemic control and quality of life in elderly patients with type 2 diabetes: a single-arm, intervention study [0.03%]
基于居家的中低强度舞蹈锻炼对老年2型糖尿病患者血糖及生活质量影响：单一队列干预研究
Atsushi Ujiie,Kenji Hara,Mio Kubo et al.
Atsushi Ujiie et al.
Background: Exercise therapy improves glycemic control and reduces cardiovascular risk factors in patients with type 2 diabetes (T2D). However, access to professionally supervised programs is limited, particularly for old...
Glucagon suppression under GLP-1RA therapy: hidden trade-offs for muscle and resilience [0.03%]
GLP-1RA治疗下的胰高血糖素抑制：肌肉和耐受力的隐性代价
Torsak Tippairote,Pruettithada Hoonkaew,Aunchisa Suksawang et al.
Torsak Tippairote et al.
Glucagon-like peptide-1 receptor agonists (GLP-1RAs) have rapidly transformed the management of type 2 diabetes and obesity, with consistent benefits in weight reduction, glycaemic control, and cardiometabolic outcomes. Yet across trials, t...
Harnessing ROCK biology to revolutionize diabetic nephropathy: decoding mechanisms, designing therapies [0.03%]
利用ROCK生物学革命糖尿病肾病：解码机制，设计疗法
Keiichiro Matoba
Keiichiro Matoba
Diabetes remains a major cause of kidney failure globally, presenting substantial challenges to healthcare systems worldwide. Although significant progress has been made in understanding its pathogenesis, residual risks persist despite curr...
Differential association of hyperglucagonemia with C-peptide levels in diabetic ketosis/ketoacidosis and hyperosmolar hyperglycemic state [0.03%]
糖尿病酮症/酮症酸中毒和高渗性高血糖状态中，高血浆胰高糖素与C肽水平的关联不同
Tatsuya Iida,Sayuri Nii,Hiroto Nishikawa et al.
Tatsuya Iida et al.
Aims/introduction: Glucagon plays a pivotal role in the development of hyperglycemia in diabetes mellitus. The purpose of this study was to investigate the hypothesis that hyperglucagonemia based on measurements of pancre...
Association of the vaspin gene rs2236242 and chemerin gene rs17173608 variants with type 2 diabetes mellitus in Northeast Iran: a case‒control study [0.03%]
东北伊朗2型糖尿病患者血管紧张素生成酶基因和胆囊收缩素基因多态性的病例对照研究
Maede Fekri Abras,Mina Lashkarboloki,Sohrab Boozarpour et al.
Maede Fekri Abras et al.
Type 2 diabetes is a complex metabolic disorder caused by a combination of genetic and nongenetic factors. Obesity is one of the main causes of diabetes, and adipose tissue releases different adipokines that regulate glucose and lipid metab...
Impact of isCGM on quality of life in overweight individuals with impaired glucose tolerance or mild diabetes: secondary analysis of a pilot randomized controlled study [0.03%]
动态葡萄糖监测对糖耐量受损或轻度糖尿病超重个体生活质量的影响：一项初步随机对照研究的事后分析
Seiji Nishikage,Yushi Hirota,Yasushi Nakagawa et al.
Seiji Nishikage et al.
Background: The impact of intermittently scanned continuous glucose monitoring (isCGM) on quality of life (QoL) for overweight individuals with impaired glucose tolerance (IGT) or mild type 2 diabetes (HbA1c ≤ 7.0%) rema...
A case of type 1 diabetes mellitus with a single-positive zinc transporter 8 antibody who developed diabetic ketoacidosis during chemotherapy for colorectal cancer [0.03%]
一例单一阳性锌转运体8自身抗体的1型糖尿病合并结直肠癌化疗期发生DKA患者报告
Takayasu Uchida,Takuya Awata,Yurina Nanahara et al.
Takayasu Uchida et al.
Zinc transporter 8 antibody (ZnT8A) is a key serological marker of type 1 diabetes mellitus (T1DM). Cases of ZnT8A single positivity are relatively rare. This study aimed to investigate a case of ZnT8A single-positive T1DM in a 51-year-old ...
Exploring the impact of ADIPOQ gene variants on plasma adiponectin levels and oxidative stress in type 2 diabetes mellitus and diabetic nephropathy in South Indian population: a case-control study [0.03%]
在南印度人群2型糖尿病和糖尿病肾病中研究ADIPOQ基因多态性对血浆脂联素水平及氧化应激的影响：病例对照研究
Santhini Gopalakrishnan,Santhi Priya Sobha,Karpagavel Lakshmanan
Santhini Gopalakrishnan
Diabetic nephropathy (DN) is a significant and major microvascular complication of Type 2 diabetes mellitus (T2DM) with obesity being a major risk factor. Adiponectin is a major adipokine secreted by adipose tissue, encoded by the APM1/ADIP...