A Study of Chemical Substances Migrated from Plastic Tableware to Evaluate the Food Safety for Pets [0.03%]
一次性宠物塑料食具向食物中迁出化学物质的研究及其对宠物食品安全性的影响评价
Yamato Miyazaki,Atsushi Yamamoto
Yamato Miyazaki
To evaluate the safety of food for pets, the migration of chemical substances from pet tableware was investigated by mass spectrometry. The presence of polymer additives Irgafos 168 and Erucamide were suspected based on mass spectra and wer...
Rapid Analysis of α-Tocopherol and Its Oxidation Products Using Supercritical Carbon Dioxide and Proton Transfer Reaction Ionization Mass Spectrometry [0.03%]
基于超临界二氧化碳和质子转移反应电离的α-生育酚及其氧化产物的快速分析方法
Chihiro Ota,Toshinobu Hondo,Yumi Miyake et al.
Chihiro Ota et al.
We have developed a rapid and sensitive analytical method for α-tocopherol and its oxidative products by combining online hyphenation of supercritical fluid extraction-supercritical fluid chromatography (SFC) with proton transfer reaction ...
Native Mass Spectrometry of BRD4 Bromodomains Linked to a Long Disordered Region [0.03%]
连接长无序区域的BRD4溴结构域原生质谱分析
Nanako Azegami,Rina Taguchi,Noa Suzuki et al.
Nanako Azegami et al.
The contribution of disordered regions to protein function and structure is a relatively new field of study and of particular significance as their function has been implicated in some human diseases. Our objective was to analyze various de...
UV-Absorbing Ligand Capped Gold Nanoparticles for the SALDI-MS Analysis of Small Molecules [0.03%]
用于SALDI-MS分析小分子的紫外吸收配体封端的金纳米粒子
Tomomi Kakuta,Nichayanan Manyuan,Hideya Kawasaki
Tomomi Kakuta
We report that modifying the surface of gold nanoparticles (Au NPs) with 2-mercaptopyridine-3-carboxylic acid (MPyCA) enhances surface-assisted laser desorption/ionization (SALDI) performance in the analysis of small molecules. The MPyCA li...
Tohru Yamagaki,Tsukiho Osawa
Tohru Yamagaki
The alkaloids epinastine, 3-methylxanthine and camptothecin were analyzed by matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS). The ionization efficiencies of epinastine and 3-methylxanthine were improved upon the add...
Attempts to Detect Lipid Metabolites from a Single Cell Using Proton-Transfer-Reaction Mass Spectrometry Coupled with Micro-Scale Supercritical Fluid Extraction: A Preliminary Study [0.03%]
利用质子转移反应气质联用技术结合微尺度超临界流体萃取法分析单细胞脂代谢组的初步尝试
Toshinobu Hondo,Chihiro Ota,Kohta Nakatani et al.
Toshinobu Hondo et al.
Proton-transfer-reaction (PTR) mass spectrometry (MS), a widely used method for detecting trace-levels of volatile organic compounds in gaseous samples, can also be used for the analysis of small non-volatile molecules by using supercritica...
Mass Spectrometry of Transferrin and Apolipoprotein CIII from Dried Blood Spots for Congenital Disorders of Glycosylation [0.03%]
先天性糖基化障碍血斑转铁蛋白和载脂蛋白CIII的质谱分析
Yoshinao Wada,Machiko Kadoya,Nobuhiko Okamoto
Yoshinao Wada
Dried blood spot (DBS) is the standard specimen for the newborn screening of inborn errors of metabolism (IEM) by tandem mass spectrometry. Availability of DBS for the mass spectrometric analysis of the diagnostic marker proteins, transferr...
Matrix-Assisted Laser Desorption/Ionization (MALDI) Mass Spectrometry Imaging of L-4-Phenylalanineboronic Acid (BPA) in a Brain Tumor Model Rat for Boron Neutron Capture Therapy (BNCT) [0.03%]
基质辅助激光解析电离 MALDI 质谱成像法测定脑肿瘤模型大鼠体内硼化合物分布用于 BNCT 研究
Yumi Miyake,Sachie Kusaka,Isao Murata et al.
Yumi Miyake et al.
Boron neutron capture therapy (BNCT) is a cell-selective particle therapy for cancer using boron containing drugs. Boron compounds are accumulated in high concentration of tens ppm level of boron in target tumors to cause lethal damage to t...
Data Processing of Product Ion Spectra: Quality Improvement by Averaging Multiple Similar Spectra of Small Molecules [0.03%]
小分子产品离子谱的质量改进平均算法及数据处理方法
Fumio Matsuda,Shuka Komori,Yuki Yamada et al.
Fumio Matsuda et al.
In metabolomics studies using high-resolution mass spectrometry (MS), a set of product ion spectra is comprehensively acquired from observed ions using the data-dependent acquisition (DDA) mode of various tandem MS. However, especially for ...
Searching, Structural Determination, and Diagnostic Performance Evaluation of Biomarker Molecules for Niemann-Pick Disease Type C Using Liquid Chromatography/Tandem Mass Spectrometry [0.03%]
液相色谱-串联质谱技术的尼曼匹克C病生物标志物分子筛选、结构鉴定及诊断效能评估研究
Masamitsu Maekawa,Nariyasu Mano
Masamitsu Maekawa
Niemann-Pick disease type C (NPC) is an autosomal recessive disorder that is characterized by progressive neuronal degeneration. Patients with NPC have a wide age of onset and various clinical symptoms. Therefore, the discovery and diagnosi...