Association between Plasma Metabolic Profiles of the Antidepressant Escitalopram and Clinical Response in Subjects with Depression [0.03%]
艾司西酞普兰抗抑郁药效物质代谢组学研究及个体化治疗阈浓度探索
Raju Bandu,Hyun Jeong Lee,Hyeong Min Lee et al.
Raju Bandu et al.
Liquid chromatography/electrospray ionization-mass spectrometry revealed plasma metabolic profiles for the antidepressant drug escitalopram (ECTP) and associated clinical responses in subjects with major depressive disorder (MDD). Metabolic...
Identification of Negative Ion at m/z 20 Produced by Atmospheric Pressure Corona Discharge Ionization under Ambient Air [0.03%]
大气压空气 coronal 离子化产生 m/z 20 负离子的鉴定
Shiho Fujishima,Kanako Sekimoto,Mitsuo Takayama
Shiho Fujishima
The negative ion at m/z 20 observed at atmospheric pressure corona discharge ionization mass spectra has been identified by supplying the vapors of deuterium oxide (D2O) and H218O. From the mass shifts of the ion at m/z 20 observed with D2O...
Immuno-Mass Spectrometry Workflow for Quantification of Serum α-Fetoprotein Using Antibody-Immobilized Magnetic Beads and Modified Eluents [0.03%]
基于磁珠免疫亲和与改进洗脱的血清α-胎儿蛋白质谱定量方法研究
Yoshio Takahata,Misato Hara,Kouhei Nishino et al.
Yoshio Takahata et al.
Immuno-mass spectrometry (MS) is a powerful method for the quantitative analysis of low-abundance proteins in biological specimens. In these procedures, collecting specifically and efficiently the target protein antigens from the antigen-an...
Rate of Advancement of Detection Limits in Mass Spectrometry: Is there a Moore's Law of Mass Spec? [0.03%]
质谱检测限的推进速度：是否有适用于质谱的摩尔定律？
Mark Beattie,Oliver A H Jones
Mark Beattie
Mass spectrometry is a well-established analytical technique for studying the masses of atoms, molecules, or fragments of molecules. One of the key metrics of mass spectrometers is the limit of detection e.g., the minimum amount of signal f...
Uranium-Lead Systematics of Lunar Basaltic Meteorite Northwest Africa 2977 [0.03%]
月球火成岩陨石西北非2977的铀铅同位素体系学研究
Narumi Moromoto,Yosuke Kawai,Kentaro Terada et al.
Narumi Moromoto et al.
Northwest Africa (NWA) 2977 is a lunar basaltic meteorite that was found in 2005 and has been classified as an olivine cumulate gabbro. This meteorite contains a shock melt vein (SMV) induced by an intense shock event. We report herein on a...
Comprehensive Membrane N-Glycoproteomics Using Human Breast Cancer Cell Line Pairs [0.03%]
人乳腺癌细胞系膜N-糖蛋白组的全面分析
Daisuke Takakura,Haruka Yoshida,Shoko Ohashi et al.
Daisuke Takakura et al.
Aberrant glycosylation of membrane proteins is a hallmark of cancer and a useful molecular marker for the diagnosis of breast cancer (BC). However, the molecular mechanisms by which altered glycosylation affects the malignant transformation...
Size Analysis of Silver and Gold Nanoparticles Using Laser Ablation Single Particle ICP Mass Spectrometry: Evaluation of the Laser-Induced Disintegration of Nanoparticles [0.03%]
飞秒激光消融单颗粒电感耦合等离子体质谱法测定纳米金和银粒子尺寸：纳粒激光解离效应的评估
Shuji Yamashita,Takafumi Hirata
Shuji Yamashita
Single particle inductively coupled plasma mass spectrometry combined with the laser ablation technique (LA-spICP-MS) has been used for the determination of particle size and the spatial distribution of metal nanoparticles (MNPs) in various...
An Investigation of the Non-selective Etching of Synthetic Polymers by Electrospray Droplet Impact/Secondary Ion Mass Spectrometry (EDI/SIMS) [0.03%]
基于电喷雾液滴撞击/二次离子质谱的合成高分子非选择刻蚀研究
Kenzo Hiraoka,Yuji Sakai,Hiroyuki Kubota et al.
Kenzo Hiraoka et al.
Among the various types of cluster secondary ion mass spectrometry (SIMS), electrospray droplet impact/secondary ion mass spectrometry (EDI/SIMS) is unique due to its high ionization efficiency and non-selective atomic/molecular-level surfa...
Construction of a Mass Spectrum Library Containing Predicted Electron Ionization Mass Spectra Prepared Using a Machine Learning Model and the Development of an Efficient Search Method [0.03%]
基于机器学习模型的预测电子轰击质谱库的构建及其高效搜索方法开发
Ayumi Kubo,Azusa Kubota,Haruki Ishioka et al.
Ayumi Kubo et al.
Electron ionization (EI) mass spectrum library searching is usually performed to identify a compound in gas chromatography/mass spectrometry. However, compounds whose EI mass spectra are registered in the library are still limited compared ...
Direct Analysis of Bio-Molecules in Solid Materials Using Electrospray Ionisation Mass Spectrometry Coupled with Laser Ablation and a Liquid Sampling Technique [0.03%]
利用激光剥蚀和液体采样技术耦合的电喷雾离子化质谱法直接分析固体材料中的生物分子
Takafumi Hirata,Menghao Yang,Hui Hsin Khoo
Takafumi Hirata
In situ and rapid analysis of organic compounds using a combination of a newly-developed laser ablation in liquid (LAL) sampling technique combined with electrospray ionisation mass spectrometry (ESI-MS) is reported. The LAL is a technique ...