Flexible xxx-asp/asn and gly-xxx residues of equine cytochrome C in matrix-assisted laser desorption/ionization in-source decay mass spectrometry [0.03%]
马血红蛋白C的柔性XXX-ASP/ASN和Gly-XXX残基的矩阵辅助激光解吸电离源内碎裂质谱研究
Mitsuo Takayama
Mitsuo Takayama
The backbone flexibility of a protein has been studied from the standpoint of the susceptibility of amino acid residues to in-source decay (ISD) in matrix-assisted laser desorption/ionization mass spectrometry (MALDI MS). Residues more susc...
Correlation between Sweet Spots of Glycopeptides and Polymorphism of the Matrix Crystal in MALDI Samples [0.03%]
基质晶体多态性与糖肽甜点之间的相关性研究
Takashi Nishikaze,Hisako Okumura,Hiroshi Jinmei et al.
Takashi Nishikaze et al.
A standard dried-droplet preparation using 2,5-dihydroxybenzoic acid (2,5-DHBA) as the matrix results in a large variation in signal intensity and poor shot-to-shot reproducibility in matrix-assisted laser desorption/ionization (MALDI). We ...
Hydrogen radical removal causes complex overlapping isotope patterns of aromatic carboxylic acids in negative-ion matrix-assisted laser desorption/ionization mass spectrometry [0.03%]
氢自由基清除导致负离子基质辅助激光解吸电离傅里叶变换离子回旋共振质谱中芳香族羧酸的复杂重叠同位素模式
Tohru Yamagaki,Takehiro Watanabe
Tohru Yamagaki
We studied the ionization process of aromatic carboxylic acids, including ones with or without hydroxy groups in matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS), because many natural products, metabolites, and drags...
Matrix-Assisted Laser Desorption/Ionization (MALDI) Imaging Mass Spectrometry (IMS): A Challenge for Reliable Quantitative Analyses [0.03%]
基质辅助激光解析离子化（MALDI）成像质谱（IMS）：可靠定量分析的挑战
Akiko Kubo,Mayumi Kajimura,Makoto Suematsu
Akiko Kubo
Matrix-assisted laser desorption/ionization (MALDI) imaging mass spectrometry (IMS) is capable of determining the distribution of hundreds of molecules at once directly from tissue sections. Since tissues are analyzed intact without homogen...
In Situ Pressure Probe Sampling and UV-MALDI MS for Profiling Metabolites in Living Single Cells [0.03%]
原位压力探针取样和UV-MALDI质谱法用于活单细胞代谢组分析
Yousef Gholipour,Rosa Erra-Balsells,Hiroshi Nonami
Yousef Gholipour
In this work we describe the use of a combination of a cell pressure probe and a UV-matrix-assisted laser desorption/ionization time of flight (UV-MALDI-TOF) mass spectrometer for the in situ picoliter sampling and shotgun metabolite profil...
Matrix effect on in-source decay products of peptides in matrix-assisted laser desorption/ionization [0.03%]
基质对基质辅助激光解吸电离中肽的源内衰变产物的影响
Daiki Asakawa,Motoshi Sakakura,Mitsuo Takayama
Daiki Asakawa
MALDI-ISD of peptides were studied using several salicylic acid derivatives, 2,5-dihydroxybenzoic acid (2,5-DHB), 5-aminosalicylic acid (5-ASA), 5-formylsalicylic acid (5-FSA), and 5-nitrosalicylic acid (5-NSA) as matrices. The difference i...
Influence of secondary structure on in-source decay of protein in matrix-assisted laser desorption/ionization mass spectrometry [0.03%]
二级结构对基质辅助激光解析离子化质谱分析中蛋白质裂解的影响研究
Mitsuo Takayama,Issey Osaka,Motoshi Sakakura
Mitsuo Takayama
The susceptibility of the N-Cα bond of the peptide backbone to specific cleavage by in-source decay (ISD) in matrix-assisted laser desorption/ionization mass spectrometry (MALDI MS) was studied from the standpoint of the secondary structur...