A Novel Derivatization Reagent in the Determination of the Number of OH End Groups in Poly(ethylene glycol) by Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry [0.03%]
基质辅助激光解析电离飞行时间质谱法定量测定聚乙二醇端羟基的新方法研究
Shuji Kagawa
Shuji Kagawa
The potential of a novel derivatization reagent, trifluoroacetic anhydride (TFAA), in determining the number of OH groups in poly(ethylene glycol) (PEG) was investigated by matrix-assisted laser desorption/ionization mass spectrometry (MALD...
Quantification of Candesartan in Mouse Plasma by MALDI-TOFMS and in Tissue Sections by MALDI-Imaging Using the Stable-Isotope Dilution Technique [0.03%]
稳定同位素稀释技术在基质辅助激光解析电离飞行时间质谱法及成像质量控制中的应用：西拉普利在小鼠血浆及组织切片中定量分析案例研究
Toyofumi Nakanishi,Shinji Takai,Denan Jin et al.
Toyofumi Nakanishi et al.
To determine the contents of candesartan in mouse plasma, and blood vessel and kidney sliced sections and also better understand its pharmacokinetics, we applied matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (...
Collision-Induced Dissociation Study of the Adduct Ions Produced in NO3 (-)-Free Area of Atmospheric Pressure Negative Corona Discharges under Ambient Air Conditions [0.03%]
大气压负晕放电条件下环境空气中的NO3(-)自由区产生加合离子的碰撞诱导解离研究
Kanako Sekimoto,Natsuki Matsuda,Mitsuo Takayama
Kanako Sekimoto
Collision-induced dissociation (CID) experiments of adducts [M+R](-) with negative atmospheric ions R(-) (O2 (-), HCO3 (-) and COO(-)(COOH)) produced in NO3 (-)-free discharge area in atmospheric pressure corona discharge ionization (APCDI)...
5-nitrosalicylic Acid as a novel matrix for in-source decay in matrix-assisted laser desorption/ionization mass spectrometry [0.03%]
5-硝基水杨酸作为基质辅助激光解析电离质量测定中诱导解离的新矩阵
Daiki Asakawa
Daiki Asakawa
The matrix-assisted laser desorption/ionization in-source decay (MALDI-ISD) of peptides and glycans was studied using an oxidizing chemical, 5-nitrosalicylic acid (5-NSA) as the matrix. The use of 5-NSA for the MALDI-ISD of peptides and gly...
Metabolic profiling of oxidized lipid-derived volatiles in blood by gas chromatography/mass spectrometry with in-tube extraction [0.03%]
基于气相色谱/质谱在线柱衍生化技术的血液中氧化脂类挥发性代谢产物分析研究
Shoji Kakuta,Yasuhiko Bando,Shin Nishiumi et al.
Shoji Kakuta et al.
Once lipids are oxidized, various volatiles are produced by cleavage of the fatty acid side chain. Considering the variety of lipids present in the body, a large number of possible volatiles might originate from oxidized lipids. However, on...
Tandem mass spectrometry of nitric oxide and hydrogen sulfide releasing aspirins: a hint into activity behavior [0.03%]
用于释放一氧化氮和硫化氢的阿司匹林的串联质谱分析：对活性行为的提示
Maria Elisa Crestoni,Barbara Chiavarino,Stefano Guglielmo et al.
Maria Elisa Crestoni et al.
Aspirin (acetylsalicylic acid, ASA) is the most popular non-steroidal anti-inflammatory drug. However, due to its action on cyclooxygenase and its acid nature, aspirin is associated with adverse gastrointestinal effects. In an effort to min...
Quantification of small molecule drugs in biological tissue sections by imaging mass spectrometry using surrogate tissue-based calibration standards [0.03%]
基于替代组织校准标准的成像质谱技术在生物组织切片中测定小分子药物定量的方法研究
Nozomi Takai,Yukari Tanaka,Hideo Saji
Nozomi Takai
Quantitative analysis of administered drugs in biological tissues is essential for understanding the mechanisms underlying their efficacy or toxicity. Imaging mass spectrometry (IMS) may allow the quantification of targeted drugs in tissue ...
MALDI Imaging Mass Spectrometry-A Mini Review of Methods and Recent Developments [0.03%]
基质辅助激光解吸电离成像质谱——方法及最新进展简述
Cecilia Eriksson,Noritaka Masaki,Ikuko Yao et al.
Cecilia Eriksson et al.
As the only imaging method available, Imaging Mass Spectrometry (IMS) can determine both the identity and the distribution of hundreds of molecules on tissue sections, all in one single run. IMS is becoming an established research technolog...
Extractive electrospray ionization mass spectrometry for uranium chemistry studies [0.03%]
用于铀化学研究的解吸电喷雾电离质谱法
Huanwen Chen,Mingbiao Luo,Saijin Xiao et al.
Huanwen Chen et al.
Uranium chemistry is of sustainable interest. Breakthroughs in uranium studies make serious impacts in many fields including chemistry, physics, energy and biology, because uranium plays fundamentally important roles in these fields. Substa...
Advances in isotope ratio mass spectrometry and required isotope reference materials [0.03%]
同位素比值质谱分析技术及所需的同位素标准物质研究进展
Jochen Vogl
Jochen Vogl
The article gives a condensed version of the keynote lecture held at the International Mass Spectrometry Conference 2012 in Kyoto. Starting with some examples for isotope research the key requirements for metrologically valid procedures ena...