Study of Isobaric Interference in Quantification of Citrulline by Parallel Fragmentation Monitoring [0.03%]
等压干扰对平行反应监测法测定瓜氨酸定量的影响研究
Eddy Wing Yin Ng,Hugh Simon Lam,Pak Cheung Ng et al.
Eddy Wing Yin Ng et al.
Parallel Fragmentation Monitoring (PFM), which is an analogue of selected reaction monitoring (SRM), is a recently developed method for quantification of small molecules by MALDI-TOF/TOF mass spectrometry (MS). It is well known that isobari...
Shuichi Shimma,Yuki Sugiura
Shuichi Shimma
Matrix-assisted laser desorption/ionization (MALDI) imaging mass spectrometry (IMS) can be used to visualize the distribution of biomolecules (proteins, peptides, metabolites) and drugs on tissue surfaces. In MALDI-IMS, sample preparation i...
Pui-Kin So,Bin Hu,Zhong-Ping Yao
Pui-Kin So
Development of electrospray ionization on solid substrates (solid-substrate ESI) avoids the clogging problem encountered in conventional capillary-based ESI, allows more convenient sampling and permits new applications. So far, solid-substr...
Silver Oxide Based Nanoparticle Assisted Laser Desorption/Ionization Mass Spectrometry for the Detection of Low Molecular Weight Compounds [0.03%]
基于氧化银纳米粒子的基质辅助激光解吸电离对小分子化合物的检测
Shu Taira,Hiroyuki Taguchi,Reiko Fukuda et al.
Shu Taira et al.
A specific property of silver oxide-based nanoparticles permits the ionization of an analyte, giving rise to various applications of a smart analytical methodology. The nanoparticles (d=6.7 nm) contained an Ag2O core. The detection of sever...
Yu-Ju Chen,Jentaie Shiea
Yu-Ju Chen
Separation of Isobaric Compounds Using a Spiral Orbit Type Time-of-Flight Mass Spectrometer, MALDI-SpiralTOF [0.03%]
利用螺旋轨道飞行时间质谱仪分离同位素质量化合物(MALDI-SpiralTOF)
Takaya Satoh,Ayumi Kubo,Hisanao Hazama et al.
Takaya Satoh et al.
The development of a MALDI-TOF mass spectrometer that utilizes spiral ion trajectory, SpiralTOF, is reported. The total flight path length was 17 m, which is five times longer than that in commonly used reflectron ion optical system. The Sp...
Super-Atmospheric Pressure Ion Sources: Application and Coupling to API Mass Spectrometer [0.03%]
超高压力电离源:应用及与大气压离子化质谱仪的联用研究
Lee Chuin Chen,Md Matiur Rahman,Kenzo Hiraoka
Lee Chuin Chen
Pressurizing the ionization source to gas pressure greater than atmospheric pressure is a new tactic aimed at further improving the performance of atmospheric pressure ionization (API) sources. In principle, all API sources, such as ESI, AP...
Analysis of Flexibility of Proteins by means of Positive and Negative Ion MALDI In-Source Decay Mass Spectrometry [0.03%]
采用正负离子基质辅助激光解析飞行时间质谱分析蛋白质的柔性
Ryunosuke Iimuro,Mitsuo Takayama
Ryunosuke Iimuro
The amino acid residues susceptible to in-source decay (ISD) in matrix-assisted laser desorption/ionization (MALDI) mass spectrometry have been identified from both positive and negative ion ISD spectra of cytochrome c, myoglobin, thioredox...
Application of Tapping-Mode Scanning Probe Electrospray Ionization to Mass Spectrometry Imaging of Additives in Polymer Films [0.03%]
针式扫描探针电喷雾离子化质谱在聚合物薄膜中添加剂成像中的应用
Ryo Shimazu,Yoshinari Yamoto,Tomoya Kosaka et al.
Ryo Shimazu et al.
We report the application of tapping-mode scanning probe electrospray ionization (t-SPESI) to mass spectrometry imaging of industrial materials. The t-SPESI parameters including tapping solvent composition, solvent flow rate, number of tapp...
Imaging Mass Spectrometric Analysis of Neurotransmitters: A Review [0.03%]
神经递质成像质谱分析进展及相关问题思考——兼评《成像质谱技术在神经化学中的应用》
Gustavo A Romero-Perez,Shiro Takei,Ikuko Yao
Gustavo A Romero-Perez
Imaging mass spectrometry (IMS) is a toolbox of versatile techniques that enable us to investigate analytes in samples at molecular level. In recent years, IMS, and especially matrix-assisted laser desorption/ionisation (MALDI), has been us...