Lee Chuin Chen
Lee Chuin Chen
In a tutorial paper on the application of free-jet technique for API-MS, John Fenn mentioned that "…for a number of years and a number of reasons, it has been found advantageous in many situations to carry out the ionization process in gas...
Development of an Imaging Mass Spectrometry Technique for Visualizing Localized Cellular Signaling Mediators in Tissues [0.03%]
一种用于在组织中可视化局部细胞信号传导介质的成像质谱技术的发展
Yuki Sugiura,Kurara Honda,Makoto Suematsu
Yuki Sugiura
In vivo concentrations of cellular signaling mediators such as inflammatory mediators are normally maintained at very low levels due to their strong ability to induce a biological response. The production, diffusion, and decomposition of su...
Middle-Down and Chemical Proteomic Approaches to Reveal Histone H4 Modification Dynamics in Cell Cycle: Label-Free Semi-Quantification of Histone Tail Peptide Modifications Including Phosphorylation and Highly Sensitive Capture of Histone PTM Binding Proteins Using Photo-Reactive Crosslinkers [0.03%]
基于组蛋白H4修饰动态研究的中下流及化学蛋白质组学方法：组蛋白肽段修饰的无标半定量分析及高灵敏PTM互作蛋白的光交联捕获技术
Kazuki Yamamoto,Yoko Chikaoka,Gosuke Hayashi et al.
Kazuki Yamamoto et al.
Mass spectrometric proteomics is an effective approach for identifying and quantifying histone post-translational modifications (PTMs) and their binding proteins, especially in the cases of methylation and acetylation. However, another vita...
Probe Heating Method for the Analysis of Solid Samples Using a Portable Mass Spectrometer [0.03%]
便携式质谱仪分析固体样品的探针加热进样方法研究
Shun Kumano,Masuyuki Sugiyama,Masuyoshi Yamada et al.
Shun Kumano et al.
We previously reported on the development of a portable mass spectrometer for the onsite screening of illicit drugs, but our previous sampling system could only be used for liquid samples. In this study, we report on an attempt to develop a...
Yuko Fukuyama
Yuko Fukuyama
Matrices are necessary materials for ionizing analytes in matrix-assisted laser desorption/ionization-mass spectrometry (MALDI-MS). The choice of a matrix appropriate for each analyte controls the analyses. Thus, in some cases, development ...
Method for the Compound Annotation of Conjugates in Nontargeted Metabolomics Using Accurate Mass Spectrometry, Multistage Product Ion Spectra and Compound Database Searching [0.03%]
基于精确质量数质谱、多级碎片离子谱和化合物数据库搜索的非目标代谢组学复合物定性方法
Tairo Ogura,Takeshi Bamba,Akihiro Tai et al.
Tairo Ogura et al.
Owing to biotransformation, xenobiotics are often found in conjugated form in biological samples such as urine and plasma. Liquid chromatography coupled with accurate mass spectrometry with multistage collision-induced dissociation provides...
Characterization of Mycolic Acids in Total Fatty Acid Methyl Ester Fractions from Mycobacterium Species by High Resolution MALDI-TOFMS [0.03%]
采用高分辨率基质辅助激光解析电离飞行时间质谱分析棒状杆菌属细菌全脂肪酸甲酯中的分枝菌酸类物质
Kanae Teramoto,Mitsuo Suga,Takafumi Sato et al.
Kanae Teramoto et al.
Mycolic acids (MAs) are characteristic components of bacteria in the suborder Corynebacterineae, such as Mycobacterium. MAs are categorized into subclasses based on their functional bases (cyclopropane ring, methoxy, keto, and epoxy group)....
Multi-Component Profiling of Trace Volatiles in Blood by Gas Chromatography/Mass Spectrometry with Dynamic Headspace Extraction [0.03%]
采用动态顶空萃取气相色谱/质谱法对血液中痕量挥发性成分进行多组分分析
Shoji Kakuta,Toshiyuki Yamashita,Shin Nishiumi et al.
Shoji Kakuta et al.
A dynamic headspace extraction method (DHS) with high-pressure injection is described. This dynamic extraction method has superior sensitivity to solid phase micro extraction, SPME and is capable of extracting the entire gas phase by purgin...
Increasing the Performance of Portable Ion Mobility Analyzers: Development of the Periodic Focusing Differential Mobility Analyzer (PFDMA) [0.03%]
周期性聚焦差分迁移率分析仪(PFDMA)的开发及便携式离子漂移装置性能的研究
Kent J Gillig,Chung-Hsuan Chen
Kent J Gillig
Ion mobility spectrometry (IMS) as a stand-alone technique has become increasingly important for applications in security, defense, and environmental monitoring, and also in biological applications such as molecular structure and -omic anal...
Chiral Differentiation of Amino Acids by In-Source Collision-Induced Dissociation Mass Spectrometry [0.03%]
利用碰撞诱导解离的基质辅助激光解析电离圆二色性质谱手征区分氨基酸离子
Xianglei Kong,Zhaiyi Huo,Wei Zhai
Xianglei Kong
Chiral recognition of d- and l-amino acids is achieved by a method combining electrospray ionization (ESI) and in-source collision-induced dissociation (CID) mass spectrometry (MS). Trimeric cluster ions [Cu(II)(A)(ref)2-H](+) are formed by...