Metabolic Visualization Reveals the Distinct Distribution of Sugars and Amino Acids in Rice Koji [0.03%]
代谢可视化揭示米曲中糖和氨基酸的独特分布
Adinda Putri Wisman,Yoshihiro Tamada,Shuji Hirohata et al.
Adinda Putri Wisman et al.
The compounds inside rice koji have been thoroughly investigated as an essential material in making many food-related products, including sake. However, these studies focused only on quantitative aspects, leaving features that can still be ...
Selective Extraction of a Monoisotopic Ion While Keeping the Other Ions in Flight on a Multi-Turn Time-of-Flight Mass Spectrometer [0.03%]
多圈飞行时间质谱仪在离子飞行过程中选择性提取单同位素离子的研究
Toshinobu Hondo,Hiroshi Kobayashi,Michisato Toyoda
Toshinobu Hondo
Using a multi-turn time-of-flight (TOF) mass spectrometer, we have extracted a single xenon isotope ion, 129Xe+, from its orbit at given a lap number without disturbing the rest of isotopes. After detecting the 129Xe+ at 20 laps, the rest o...
Practical Protocol for Making Calibration Curves for Direct and Sensitive Quantitative LC Orbitrap-MS of Large Neuropeptides [0.03%]
用于直接和敏感的大型神经肽定量液相色谱轨道阱质谱的大校准曲线的实用协议
Tohru Yamagaki,Takashi Yamazaki
Tohru Yamagaki
Peptides larger than 3-4 kDa, such as neuropeptide Y (NPY), orexin-B, and alpha-MSH, have practical issues that arise when conducting direct and sensitive quantitative liquid chromatography (LC) orbitrap-FT mass spectrometry (MS) due to the...
Quantitative Visualization of Lanthanum Accumulation in Lanthanum Carbonate-Administered Human Stomach Tissues Using Mass Spectrometry Imaging [0.03%]
利用基于质谱的成像技术定量可视化碳酸镧给药人体胃粘膜中镧元素聚集状况
Shuichi Shimma,Yoshiki Makino,Kazuto Kojima et al.
Shuichi Shimma et al.
Platinum, a transition metal that is widely used in anti-cancer agents, also results in the development of nephropathy due to severe adverse reactions caused by platinum-induced nephrotoxicity. Reports on imaging with metals other than plat...
Analytical Capability of High-Time Resolution-Multiple Collector-Inductively Coupled Plasma-Mass Spectrometry for the Elemental and Isotopic Analysis of Metal Nanoparticles [0.03%]
高时间分辨率多接收等离子体质谱仪分析金属纳米颗粒元素和同位素的能力
Takafumi Hirata,Shuji Yamashita,Mirai Ishida et al.
Takafumi Hirata et al.
We measured the Re/Os (185Re/188Os) and 187Os/188Os ratios from nanoparticles (NPs) using a multiple collector-inductively coupled plasma-mass spectrometer equipped with high-time resolution ion counters (HTR-MC-ICP-MS). Using the HTR-MC-IC...
Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry to Detect Diagnostic Glycopeptide Markers of Congenital Disorders of Glycosylation [0.03%]
基质辅助激光解吸电离飞行时间质谱技术检测糖蛋白疾病的诊断标志物肽段指纹图谱
Yoshinao Wada
Yoshinao Wada
Congenital disorders of glycosylation (CDG), an increasingly recognized group of diseases that affect glycosylation, comprise the largest known subgroup of approximately 100 responsible genes related to N-glycosylation. This subgroup presen...
Shinji Nonose
Shinji Nonose
Temperature-resolved proton transfer reactions of multiply-protonated angiotensin I, disulfide-intact and -reduced lysozyme, and ubiquitin ions to primary, secondary and aromatic amines were examined in the gas phase. Absolute reaction rate...
Naoyuki Sugiyama
Naoyuki Sugiyama
Protein phosphorylation mediated by protein kinases is one of the most significant posttranslational modifications in many biological events. The function and physiological substrates of specific protein kinases, which are highly associated...
Analysis of Serotonin in Human Feces Using Solid Phase Extraction and Column-Switching LC-MS/MS [0.03%]
人粪便中5-羟色胺的固相萃取和柱切换LC-MS/MS分析方法研究
Yukiko Hirabayashi,Kiminori Nakamura,Tsuyoshi Sonehara et al.
Yukiko Hirabayashi et al.
Serotonin, an important neurotransmitter, is produced mainly in intestines, and serotonin levels in feces can be an indicator of the intestinal environment. Human feces, however, contain a large amount of contaminants, which vary widely owi...
An Analytical System for Single-Cell Metabolomics of Typical Mammalian Cells Based on Highly Sensitive Nano-Liquid Chromatography Tandem Mass Spectrometry [0.03%]
一种基于高灵敏纳升液相色谱串联质谱的典型哺乳动物细胞单细胞代谢组分析方法
Kohta Nakatani,Yoshihiro Izumi,Kosuke Hata et al.
Kohta Nakatani et al.
The rapid development of next-generation sequencing techniques has enabled single-cell genomic and transcriptomic analyses, which have revealed the importance of heterogeneity in biological systems. However, analytical methods to accurately...