Comparison of Dimensionality Reduction Methods in Mass Spectra of Astrocytoma and Glioblastoma Tissues [0.03%]
弥漫性 astrocytic 和 glioblastoma 肿瘤组织质谱数据的降维方法比较分析研究
Evgeny Zhvansky,Anatoly Sorokin,Vsevolod Shurkhay et al.
Evgeny Zhvansky et al.
Recently developed methods of ambient ionization allow the collection of mass spectrometric datasets for biological and medical applications at an unprecedented pace. One of the areas that could employ such analysis is neurosurgery. The fas...
Effect of Phosphorylation on the Collision Cross Sections of Peptide Ions in Ion Mobility Spectrometry [0.03%]
磷酸化对离子移动性谱法中肽类离子碰撞截面的影响研究
Kosuke Ogata,Chih-Hsiang Chang,Yasushi Ishihama
Kosuke Ogata
The insertion of ion mobility spectrometry (IMS) between LC and MS can improve peptide identification in both proteomics and phosphoproteomics by providing structural information that is complementary to LC and MS, because IMS separates ion...
Probe Electrospray Ionization (PESI) and Its Modified Versions: Dipping PESI (dPESI), Sheath-Flow PESI (sfPESI) and Adjustable sfPESI (ad-sfPESI) [0.03%]
探针式电喷雾电离(PESI)及其改进方法：浸入式PESI(dPESI)，鞘流式PESI(sfPESI)及可调式sfPESI(ad-sfPESI)
Kenzo Hiraoka,Osamu Ariyada,Dilshadbek T Usmanov et al.
Kenzo Hiraoka et al.
In 2007, probe electrospray ionization/mass spectrometry (PESI/MS) was developed. In this technique, the needle is moved down along a vertical axis and the tip of the needle touched to the sample. After capturing the sample at the needle ti...
Enhancement of Ionization Efficiency Using Zeolite in Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry of Multiple Drugs in Cancer Cells (Mass Spectrometry of Multiple Drugs in Cells Using Zeolite) [0.03%]
质子交换膜燃料电池用新型高稳定性阴极催化剂中毒机制及缓解策略研究中毒机制及缓解策略研究
Hiroki Kannen,Shusei Nomura,Hisanao Hazama et al.
Hiroki Kannen et al.
Combined therapy using photodynamic therapy (PDT) and chemotherapy has been proposed for anticancer-drug-resistant cancer cells. To evaluate the efficacy of such a combined therapy, the uptakes of an anticancer drug and a photosensitizer in...
Troubleshooting Carry-Over in the LC-MS Analysis of Biomolecules: The Case of Neuropeptide Y [0.03%]
LC-MS分析中的生物分子携带over troubleshooting案例：神经肽Y
Tohru Yamagaki,Takashi Yamazaki
Tohru Yamagaki
We describe systematic troubleshooting of the carry-over of neuropeptide Y (NPY) in LC-MS analysis. The objective was to remove candidate parts of the LC-MS system that are responsible for carry over one-by-one. The findings indicate that t...
Development of Software for the In-Depth Analysis of Protein Dynamics as Determined by MALDI Mass Spectrometry-Based Hydrogen/Deuterium Exchange [0.03%]
基于基质辅助激光解析离子化氢/氘交换质谱的蛋白质动力学深入分析软件开发
Tatsuya Yamamoto,Tohru Yamagaki,Honoo Satake
Tatsuya Yamamoto
Hydrogen/deuterium exchange (HDX) coupled with pepsin digestion is useful for rapidly analyzing the kinetic properties of small amounts of protein. However, the analysis of HDX by matrix-assisted laser desorption/ionization (MALDI) mass spe...
Natural Product Discovery by Direct Analysis in Real Time Mass Spectrometry [0.03%]
基于直接分析在線瞬間硬盤質量 spectrometry 的天然產品發現
Joanne Y Yew
Joanne Y Yew
Direct analysis in real time mass spectrometry (DART MS) is one of the first ambient ionization methods to be introduced and commercialized. Analysis by DART MS requires minimal sample preparation, produces nearly instantaneous results, and...
Identifying Double Bond Positions in Phospholipids Using Liquid Chromatography-Triple Quadrupole Tandem Mass Spectrometry Based on Oxygen Attachment Dissociation [0.03%]
基于氧连接断裂的液相色谱-三重四级杆质谱法测定卵磷脂中双键位置
Hidenori Takahashi,Yuji Shimabukuro,Daiki Asakawa et al.
Hidenori Takahashi et al.
Lipids, a class of biomolecules, play a significant role in the physiological system. In this study, gas-phase hydroxyl radicals (OH·) and atomic oxygens (O) were introduced into the collision cell of a triple quadruple mass spectrometer (...
A Special Issue for the 2nd International Biological Mass Spectrometry (BMS) Symposium 2018 in Kyoto [0.03%]
第2届国际生物质量谱(BMS)研讨会2018京都特别专辑
Chen Lee Chuin,Tohru Yamagaki
Chen Lee Chuin
Mass Spectrometric Characterization of Histone H3 Isolated from in-Vitro Reconstituted and Acetylated Nucleosome Core Particle [0.03%]
体外重新构建和乙酰化核小体核心颗粒中组蛋白H3的质谱表征
Kazumi Saikusa,Haruna Hidaka,Shunsuke Izumi et al.
Kazumi Saikusa et al.
Post-translational modifications (PTMs) of histone N-terminal tails in nucleosome core particle (NCP), such as acetylation, play crucial roles in regulating gene expression. To unveil the regulation mechanism, atomic-level structural analys...