Spontaneous pneumomediastinum: A comprehensive review of diagnosis and management [0.03%]
自发性纵隔气肿的诊断和治疗综述
Ankoor Talwar,Athira Rajeev,Shasank Rachapudi et al.
Ankoor Talwar et al.
Pneumomediastinum is a rare condition defined by the presence of air in the mediastinum. In the absence of traumatic injury, iatrogenic injury, or clear etiology, it is called spontaneous pneumomediastinum (SPM). Spontaneous pneumomediastin...
Guardians of memory: The urgency of early dementia screening in an aging society [0.03%]
记忆的守卫者——老龄化社会中早行痴呆筛查的紧迫性
Xiqi Hu,Ya-Nan Ma,Kenji Karako et al.
Xiqi Hu et al.
The global aging population has led to a significant rise in the prevalence of age-related non-communicable diseases such as dementia and other cognitive disorders. In 2019, there were 57.4 million people with dementia worldwide, and this n...
Genetic analysis of a novel FBN1 mutation in a pediatric Marfan syndrome patient [0.03%]
基因分析在马凡综合征患儿中发现新型FBN1突变
Xiangdong Zhang,Lixing Zhou,Jiao Liu et al.
Xiangdong Zhang et al.
The aim of this study was to investigate a novel FBN1 gene mutation in a pediatric patient with Marfan syndrome (MFS) to provide a theoretical basis for genetic counseling. The subject was a 5-month-old male infant. With informed consent fr...
Impact of chronic pain and depressive symptoms on the quality of life of adults with Chiari Malformation type I: A comparative study [0.03%]
慢性疼痛和抑郁症状对成人I型小脑扁桃体疝生活质量的影响：一项比较研究
Maitane García,Imanol Amayra,Manuel Pérez et al.
Maitane García et al.
Chiari Malformation type I (CM-I) is a neurological disorder characterized by cerebellar tonsillar herniation. Chronic pain, particularly headaches, is a prevalent symptom in CM-I patients, significantly impacting their quality of life. The...
Małgorzata Syczewska,Anna Stęplowska,Ewa Szczerbik et al.
Małgorzata Syczewska et al.
Neurodegeneration with brain iron accumulation (NBIA) is a heterogeneous group (genetically and phenotypically) of genetically determined disorders. Up to date there is no cure for this disease, so the applied treatments focus on symptoms c...
Epidemiological estimates of paroxysmal nocturnal hemoglobinuria in Bulgaria [0.03%]
保加利亚阵发性夜间血红蛋白尿的流行病学估计数值
Elina Beleva
Elina Beleva
Paroxysmal nocturnal hemoglobinuria is a rare clonal hematopoietic stem cell disorder with debilitating health consequences if untreated. Although cases have been described globally, precise epidemiological distribution is difficult to asse...
A patient treated with ofatumumab for myasthenia gravis in conjunction with systemic lupus erythematosus and thyroid carcinoma [0.03%]
一名同时患有系统性红斑狼疮和甲状腺癌的重症肌无力患者接受奥法木单抗治疗
Xi Rong,Meijie Qu,Liwei Jiang et al.
Xi Rong et al.
Myasthenia gravis (MG) is an autoimmune disease mediated by B cells and is associated with acetylcholine receptor (AChR) and muscle-specific receptor tyrosine kinase (MuSK) antibodies in the postsynaptic membrane at the neuromuscular juncti...
Cost-utility analysis of romiplostim for the treatment of chronic primary immune thrombocytopenia in China [0.03%]
中国治疗慢性原发性免疫性血小板减少症患者使用利托普利姆的 cost-utility 分析
Yashuang Luo,Wendi Cheng,Yuyan Fu et al.
Yashuang Luo et al.
This study aimed to assess the cost-utility of romiplostim (ROMI) compared to eltrombopag (EPAG) as a second-line treatment for chronic primary immune thrombocytopenia (cITP) in Chinese adults. A decision tree-embedded Markov model with a l...
Splenectomy unveils thrombocytosis in underlying myeloproliferative neoplasms with extrahepatic portal vein obstruction [0.03%]
脾切除术揭示非肝门静脉阻塞伴发的骨髓增殖性肿瘤患者的血小板增多症
Tetsuya Shimizu,Hiroshi Yoshida,Nobuhiko Taniai et al.
Tetsuya Shimizu et al.
Extrahepatic portal vein obstruction (EHPVO) is a rare disease with myeloproliferative neoplasm (MPN) as the most common cause. We report that hypersplenic hematologic changes in EHPVO might be eliminated by MPN. Through experience with spl...
Skeletal computed tomography findings of upper extremities in middle-aged persons with thalidomide embryopathy [0.03%]
中年患thalidomide胎儿病成人上肢骨骼计算机断层摄影检查结果分析
Chihiro Kamimura,Junko Fujitani,Isao Aizawa et al.
Chihiro Kamimura et al.
Individuals with thalidomide embryopathy are now approximately 60 years old. For years, they have been compensating for their hypoplastic limbs in various aspects of daily living, and they face secondary problems such as limb and back pain....