Peripheral stimulation in treating Parkinson's disease: Is it a realistic idea or a romantic whimsicality? [0.03%]
外周刺激治疗帕金森病：是现实的想法还是浪漫的幻想？
Tetsuya Asakawa,Huan Fang,Zhen Hong et al.
Tetsuya Asakawa et al.
Parkinson's disease (PD) is a common, however, intractable neurodegenerative disorder in the aging population. Levodopa (l-dopa) administration is regarded as the most effective strategy in treating PD with prominent motor side-effects afte...
Ziyad S Almalki,Abdullah K Alahmari,Jeff J Guo et al.
Ziyad S Almalki et al.
An orphan drug is a drug developed specifically to treat a rare medical condition. With a combined population of less than 400 million, about 2.8 million patients are estimated to be suffering from a rare disease in the Middle East. Some di...
Liang Mao,Yudong Qiu
Liang Mao
The Atlanta Classification of acute pancreatitis (AP) is widely accepted and has been used by physicians and radiologists since 1992. However, advances in knowledge of the disease process, improved imaging, and ever-changing treatment optio...
Role of duplex ultrasound in the diagnosis and assessment of carotid body tumour: A literature review [0.03%]
双谱仪超声在颈动脉体瘤诊断及评估中的作用：文献回顾
Yisha Tong
Yisha Tong
Carotid body tumour is a rare disease, a slow growing highly vascular tumour of the carotid body tissue and the most common type of the paraganglioma. This article reviews the pathological, clinical and ultrasound features of carotid body t...
Progress in the clinical imaging research of bone diseases on ankle and foot sesamoid bones and accessory ossicles [0.03%]
踝足豆状骨及副骨的临床影像学研究进展
Xiaozhong Li,Lenian Shi,Taiyun Liu et al.
Xiaozhong Li et al.
Sesamoid bones and accessory ossicles are research focuses of foot and ankle surgery. Pains of the foot and ankle are related to sesamoid bones and accessory ossicles. The specific anatomical and functional relationship of sesamoid bones an...
Pseudomyxoma peritonei as an intractable disease and its preoperative assessment to help improve prognosis after surgery: A review of the literature [0.03%]
腹膜假黏液瘤的术前评估及其预后的改善
Yuesi Zhong,Meihai Deng,Ruiyun Xu et al.
Yuesi Zhong et al.
Pseudomyxoma peritonei (PMP) is a rare and intractable disease with an estimated incidence of one per million population per year. Many aspects of PMP need to be fully and precisely understood; these include its preoperative assessment, i.e...
Dry age-related macular degeneration: A currently unmet clinical need [0.03%]
干性年龄相关性黄斑变性：目前尚未满足的临床需求
Jean-François Girmens,José-Alain Sahel,Katia Marazova
Jean-François Girmens
Age-related macular degeneration (AMD) is a leading cause of severe visual impairment and disability in older people worldwide. Although considerable advances in the management of the neovascular form of AMD have been made in the last decad...
Ziqiang Wang,Yanqin Lu,Jinxiang Han
Ziqiang Wang
Peripheral blood microRNAs (miRNAs) are endogenous, noncoding small RNAs present in blood. Because of their size, abundance, tissue specificity, and relative stability in peripheral circulation, they offer great promise of becoming a novel ...
New opportunity for orphan drug development in Japan: Early exploratory clinical trial bases promote drug translation from basic studies to clinical application [0.03%]
日本孤儿药开发的新机遇——早期探索性临床试验推动基础研究向临床应用转化
Peipei Song,Jianjun Gao,Norihiro Kokudo et al.
Peipei Song et al.
In Japan, although orphan drug legislation has been established in 1993 to encourage drug research and development (R&D) for intractable and rare diseases, nearly half of the orphan drugs in the Japanese market originated from the European ...