The generation of induced pluripotent stem cells from a patient with KCNH2 G603D, without LQT2 disease associated symptom [0.03%]
从无LQT2症状的KCNH2(G603D)携带者中诱导生成多能干细胞
Shinichiro Okata,Shinsuke Yuasa,Teiichi Yamane et al.
Shinichiro Okata et al.
The long QT syndrome type 2 (LQT2) is inheritable life threatening arrhythmic disorder and one of the most common genetic variants in long QT syndrome. There are some indications for treatment of the patients with LQT2 but it is impossible ...
Case Reports
Journal of medical and dental sciences. 2013 Mar 1;60(1):17-22. DOI: 2013
Efficient in vivo delivery of antisense oligonucleotide to choroid plexus [0.03%]
高效地将反义寡核苷酸递送至脑室脉络丛
Wenying Piao,Kazutaka Nishina,Kie Yoshida-Tanaka et al.
Wenying Piao et al.
The choroid plexus (CP) is present on the ventricular walls of the brain, produces cerebrospinal fluid (CSF), contains many blood vessels, and is a major functional component of the blood-CSF barrier. The CP is an important site in the path...
The pulmonary tissue damage associated with the aspiration of gelatinizers in rats [0.03%]
有关大鼠吸入胶凝剂所致肺组织损伤的实验研究
Ritsu Nishimura,Naoto Sugiyama,Ichiro Fujishima
Ritsu Nishimura
Various gelatinizers, which facilitate oral ingestion, are employed in patients with dysphagia. The purpose of this study was to histologically clarify the influence of various gelatinizers on the lung, using rats. We administered 0.2 ml/kg...
Comparative Study
Journal of medical and dental sciences. 2013 Mar 1;60(1):1-8. DOI: 2013
The effect of mastication on reaction latency to unanticipated external disturbances in the standing position [0.03%]
咀嚼对站立位意外外部干扰反应时的影响
Keisuke Kaji,Munenori Katoh,Koji Isozaki et al.
Keisuke Kaji et al.
Previous research has shown that mastication reduces shifts in the center of gravity of persons standing still. The present research was conducted to determine whether mastication improves reactive balance in the standing position in respon...
Comparative Study
Journal of medical and dental sciences. 2012 Dec 3;59(4):83-8. DOI: 2012
Augmentation of arginase Ⅱ expression in the human endometrial epithelium in the secretory phase [0.03%]
人子宫内膜分泌期增殖的精氨酸酶Ⅱ表达上调
Makiko Tajima,Tatsuya Harada,Tomonori Ishikawa et al.
Makiko Tajima et al.
L-arginine is the common substrate for arginase and nitric oxide synthase (NOS). Arginase converts L-arginine to urea and L-ornithine. L-Ornithine is the principal precursor for the production of polyamines and L-proline, which are required...
Niroshani Surangika Soysa,Neil Alles,Kazuhiro Aoki et al.
Niroshani Surangika Soysa et al.
Osteoclasts are multinucleated cells of hematopoietic origin which are unique in their ability to resorb bone. Osteoclasts are generated from myeloid progenitors through a progression that involves the fusion of mononuclear precursor cells....
Analysis of DWI ASPECTS and recanalization outcomes of patients with acute-phase cerebral infarction [0.03%]
急性脑梗死患者DWI-ASPECTS评分与血管再通效果分析
Keigo Shigeta,Kikuo Ohno,Yoshio Takasato et al.
Keigo Shigeta et al.
In order to rapidly judge the response to intravenous tissue plasminogen activator (Ⅳ tPA) treatment, we retrospectively analyzed clinical data, such as MRI diffusion-weighted images (DWI), and treatment outcomes in 73 patients who develop...
Quantification of in vitro produced wear sites on composite resins using contact profilometry and CCD microscopy: a methodological investigation [0.03%]
采用接触轮廓仪和CCD显微镜对复合树脂离体磨损进行量化的方法学研究
Natthavoot Koottathape,Hidekazu Takahashi,Wernerj Finger et al.
Natthavoot Koottathape et al.
Background: Although attritive and abrasive wear of recent composite resins has been substantially reduced, in vitro wear testing with reasonably simulating devices and quantitative determination of resulting wear is stil...
Comparative Study
Journal of medical and dental sciences. 2012 Jun 1;59(2):53-6. DOI: 2012
Hepatic stellate cells mediate differentiation of dendritic cells from monocytes [0.03%]
肝星状细胞介导单核细胞向树突状细胞的分化
Rie Ozeki,Sei Kakinuma,Kinji Asahina et al.
Rie Ozeki et al.
Background: We have previously reported that human umbilical cord blood (UCB)-nucleated cells differentiate into hepatocyte-like cells when cultured in a 5-cytokine cocktail medium. We further found that UCB cells rather ...
Makito Yasui,Yasunari Miyazaki,Keiko Mitaka et al.
Makito Yasui et al.
Chronic hypersensitivity pneumonitis (HP) causes progressive and irreversible pulmonary fibrosis, a disease also observed in conjunction with idiopathic pulmonary fibrosis (IPF). Previous studies have demonstrated that the myofibroblast, a ...