Alemtuzumab in relapsing-remitting multiple sclerosis in clinical practice: Annual NEDA-3 follow-up for up to 4 years [0.03%]
临床实践中使用阿伦珠单抗治疗复发缓解型多发性硬化症的随访：长达四年的年NEDA-3跟踪调查
Leticia Herrero-Poch,Maria Susana Fortes-González,Antonio Pato-Pato et al.
Leticia Herrero-Poch et al.
Objective: The effectiveness of alemtuzumab in patients with relapsing-remitting multiple sclerosis (RRMS) have been demonstrated in clinical trials. The primary endpoint was to describe the annual effectiveness of alemtu...
Teresa Bermejo Vicedo,Maria Queralt Gorgas,Luis Margusino Framiñan
Teresa Bermejo Vicedo
Multidrug-resistant extra-pulmonary tuberculosis in a hemodyalisis patient treated with bedaquiline and tedizolid. A case report and a literature rewiew [0.03%]
一例血液透析患者的多重耐药性肺外结核病的贝达喹啉和泰地唑胺治疗：病例报告及文献回顾
Paula Novo González,Irene Galindo Marín,Elena García Benayas et al.
Paula Novo González et al.
[Translated article] Contribution of N-oxide metabolite in the therapeutic drug monitoring of voriconazole in a patient with invasive aspergillosis [0.03%]
曲霉病患者伏立康唑N-氧化代谢物对其治疗药物监测的贡献
Irene Orozco Cifuentes,Adrián Domínguez García,María Jiménez Meseguer et al.
Irene Orozco Cifuentes et al.
Desensitization protocol to pomalidomide in a patient with cutaneous hypersensitivity: A case report [0.03%]
来那度胺皮肤超敏反应患者的潘拉利珠单抗脱敏治疗：1例报告
Gabriel Martínez-Orea,Carlos Devesa-García,Laura Puente-Romero et al.
Gabriel Martínez-Orea et al.
Pomalidomide is a third-generation immunomodulatory drug that has been shown to be effective in the treatment of relapsed/refractory multiple myeloma. Although it is generally well tolerated, some patients may experience hypersensitivity re...
Reduction of unnecessary repackaging as an environmental sustainability measure [0.03%]
减少不必要的再包装作为环境可持续性措施
David García-Martínez,Manuela Martínez-Camacho,Aida Rueda-Naharro et al.
David García-Martínez et al.
Objective: The main objective is to describe the project and evaluate the impact of replacing repackaged medications with unit dose presentations in 15 public hospitals within a regional health system. Secondary objective...
Immunotherapy in advanced endometrial cancer with microsatellite instability: A systematic review [0.03%]
微卫星不稳定性子宫内膜癌免疫治疗的系统综述研究
Cristina Moreno-Ramos,Manuel David Gil-Sierra,María Del Pilar Briceño-Casado
Cristina Moreno-Ramos
Background: Endometrial cancer with microsatellite instability (MSI) involves 30% of diagnosed cases. There are some uncertainty about second-line treatment, after platinum-based first-line treatment. The aim of this stud...
Authorization of off-label drugs in a tertiary hospital: 5-year perspective [0.03%]
三级医院药物超说明书使用现状及管理规范五年回顾性研究分析
Lupe Rodríguez-de Francisco,Ángela María Villalba-Moreno,Eva Rocío Alfaro-Lara
Lupe Rodríguez-de Francisco
Introduction: The off-label use of drugs requires scientific support to balance risk/benefit, being limited to exceptional cases in which there are no therapeutic alternatives. ...
Sepsis and septic shock [0.03%]
脓毒症与感染性休克
Carla Bastida,Amaia Egües Lugea,Aurora Fernández Polo et al.
Carla Bastida et al.
Sepsis and septic shock are major global health issues, with significant morbidity and mortality. Early identification and appropriate management during the first few hours are crucial for improving clinical outcomes. Sepsis treatment focus...
Hilario Martínez-Barros,María Muñoz-García,Darío Antolín-Amérigo et al.
Hilario Martínez-Barros et al.
Objetives: To design the patient onboarding in a multidisciplinary severe asthma unit, according to the needs identified by patients and professionals in the unit. ...