Relationship between plasma concentrations of ustekinumab at week 8 and its effectiveness in patients with Crohn's disease [0.03%]
乌司奴单抗治疗克罗恩病患者第8周血药浓度与疗效的关系研究
Betel Del Rosario García,Laura Ramos,Ruth Ramos Díaz et al.
Betel Del Rosario García et al.
Objective: The individualization of treatments through pharmacokinetic monitoring is a therapeutic strategy aimed at improving both the effectiveness and safety of drug therapy. For tumor necrosis factor inhibitors used i...
Complete resolution of rupiaceous psoriasis associated with arthropathy with guselkumab: A case report [0.03%]
有关节病的斑块型银屑病患者使用古塞库单抗完全缓解的病例报告
Andrea Pinilla Rello,Eva Queipo García,Mª Victoria Corriol Pallas et al.
Andrea Pinilla Rello et al.
[Translated article] Management of analgosedation and delirium in the critically ill patient [0.03%]
重症患者镇静镇痛及谵妄管理
María Martín Cerezuela,Esther Domingo Chiva,Tatiana Betancor García et al.
María Martín Cerezuela et al.
The management of pain, agitation/sedation and delirium is a fundamental part of the treatment received by patients admitted to Intensive Care Units (ICU). The use of different strategies for the prevention and treatment of pain, agitation ...
Pharmacologic and pharmacokinetic factors in blood donation: A risk-based deferral framework proposal [0.03%]
献血者的用药和药代动力学因素的评估框架提案——基于风险的延期框架提案
Roberto Lozano,María-Esther Franco,Carina Bona
Roberto Lozano
Objective: The presence of residual medications in blood donors can pose a risk to transfusion recipients, especially when drugs remain in plasma at clinically relevant levels. Current deferral recommendations for medicat...
Desensitization protocol to pomalidomide in a patient with cutaneous hypersensitivity: A case report [0.03%]
来那度胺皮肤超敏反应患者的泊马利尤姆诱导脱敏治疗：1例报告
Gabriel Martínez-Orea,Carlos Devesa-García,Laura Puente-Romero et al.
Gabriel Martínez-Orea et al.
Quality of life and effectiveness of vutrisiran as treatment for hereditary transthyretin amyloidosis [0.03%]
口服vutrisiran治疗遗传性甲状腺素转运蛋白淀粉样变性的有效性和生活质量结局：一项2期随机试验
Javier Corazón Villanueva,Ana Andrea García Sacristán
Javier Corazón Villanueva
Objectives: To assess changes in quality of life in patients with rare disease hereditary transthyretin amyloidosis after initiating vutrisiran. Secondary objectives included evaluating effectiveness and safety. ...
[Translated article] Alemtuzumab in relapsing-remitting multiple sclerosis in clinical practice: Annual NEDA-3 follow-up for up to 4 years [0.03%]
阿伦单抗治疗复发缓解型多发性硬化症的临床实践：长达4年的NEDA-3年度随访结果翻译
Leticia Herrero-Poch,Maria Susana Fortes-González,Antonio Pato-Pato et al.
Leticia Herrero-Poch et al.
Objective: The effectiveness of alemtuzumab in patients with relapsing-remitting multiple sclerosis (RRMS) have been demonstrated in clinical trials. The primary endpoint was to describe the annual effectiveness of alemtu...
[Translated article] Multidisciplinary approach to prenatal cystic fibrosis with cystic fibrosis transmembrane regulator modulators: Experience in a clinical case [0.03%]
多学科方法在产前囊性纤维化与囊性纤维化跨膜调节物调制剂中的应用：一例临床病例经验总结
Pedro Del Palacio-García,Carmen García-Muñoz,María Dolores Canales-Siguero et al.
Pedro Del Palacio-García et al.
[Translated article] Acute esophageal necrosis in a patient with lung cancer under treatment with osimertinib: Case report [0.03%]
奥希替尼治疗肺癌患者的急性食管坏死1例报告
Alicia Aguado-Paredes,Laura Moñino-Dominguez,Maria Del Carmen Damas-Fuentes
Alicia Aguado-Paredes
Atezolizumab plus platinum-based chemotherapy and etoposide as first-line treatment for metastatic small cell lung cancer: a retrospective multicenter observational study [0.03%]
阿特珠单抗联合以铂类药物为基础的化疗及依托泊苷治疗小细胞肺癌患者的首次经验：一项回顾性多中心观察研究
Laura Moñino Domínguez,Laura Amaro Álvarez,Alicia Aguado Paredes et al.
Laura Moñino Domínguez et al.
Introduction: The standard first-line treatment for metastatic small-cell lung cancer (SCLC) is platinum-based chemotherapy in combination with etoposide. The aim of this study was to evaluate the real-world effectiveness...