Liz Simon,Sarah E Jolley,Patricia E Molina
Liz Simon
Skeletal muscle dysfunction (i.e., myopathy) is common in patients with alcohol use disorder. However, few clinical studies have elucidated the significance, mechanisms, and therapeutic options of alcohol-related myopathy. Preclinical studi...
Alcohol's Effects on the Brain: Neuroimaging Results in Humans and Animal Models [0.03%]
酒精对大脑的影响：人类和动物模型的神经影像结果
Natalie M Zahr,Adolf Pfefferbaum
Natalie M Zahr
Brain imaging technology has allowed researchers to conduct rigorous studies of the dynamic course of alcoholism through periods of drinking, sobriety, and relapse and to gain insights into the effects of chronic alcoholism on the human bra...
Uniting Epidemiology and Experimental Disease Models for Alcohol-Related Pancreatic Disease [0.03%]
流行病学和酒精相关胰腺疾病实验模型的研究联合
Veronica Wendy Setiawan,Kristine Monroe,Aurelia Lugea et al.
Veronica Wendy Setiawan et al.
Findings from epidemiologic studies and research with experimental animal models provide insights into alcohol-related disease pathogeneses. Epidemiologic data indicate that heavy drinking and smoking are associated with high rates of pancr...
Faraz Bishehsari,Emmeline Magno,Garth Swanson et al.
Faraz Bishehsari et al.
In large amounts, alcohol and its metabolites can overwhelm the gastrointestinal tract (GI) and liver and lead to damage both within the GI and in other organs. Specifically, alcohol and its metabolites promote intestinal inflammation throu...
Natalia A Osna,Terrence M Donohue Jr,Kusum K Kharbanda
Natalia A Osna
Excessive alcohol consumption is a global healthcare problem. The liver sustains the greatest degree of tissue injury by heavy drinking because it is the primary site of ethanol metabolism. Chronic and excessive alcohol consumption produces...