Evaluation of major adverse events of clozapine based on accordance to an international titration guideline [0.03%]
基于国际剂量滴定指南评估氯氮平不良事件
Matthew Nuebel,Jonathan G Leung,Christopher Hughes et al.
Matthew Nuebel et al.
Introduction: Clozapine is the only antipsychotic approved for treatment-resistant schizophrenia, but without appropriate monitoring, it can be associated with potentially fatal outcomes. An International Adult Clozapine ...
Pharmacologic management of adolescent catatonia: A dual-case series [0.03%]
青少年katatonia的药理学管理：双重病例系列
Lauren Leiby,Lauryn Shiplett,Wendy Lin et al.
Lauren Leiby et al.
Introduction: Catatonia is a syndrome characterized by psychomotor and behavioral disturbances and is associated with a substantially increased mortality risk in adolescent patients. There is a dearth of published literat...
"It's been a long time since I drank like that": A case report of binge drinking associated with aripiprazole [0.03%]
一例与阿立哌唑有关的狂饮病例报告
Alyssa Falleni,Audrey Abelleira,Robin Hieber
Alyssa Falleni
Aripiprazole has been linked to the development of impulse control problems (ICPs), most commonly gambling. Aripiprazole's effect on serotonergic and dopaminergic pathways has had mixed results on drinking behaviors. A male patient receivin...
The potential influence of estrogen-containing oral contraception on clozapine metabolism in a patient with known pharmacogenomic status [0.03%]
口服雌激素避孕药对已知药物基因组学状态的氯氮平代谢潜在影响的影响
Alyssa K Kuhn,Meina L Determan,Jessica A Wright et al.
Alyssa K Kuhn et al.
Clozapine is primarily metabolized via cytochrome P450(CYP)1A2 and to a lesser extent CYP3A4, CYP2C19, and CYP2D6. Metabolic inhibitors of clozapine, such as fluvoxamine and ciprofloxacin, are important to recognize to avoid adverse drug ev...
Pharmacokinetic and pharmacodynamic considerations with psychiatric disorders and migraines [0.03%]
精神疾病和偏头痛的药代动力学及药效学考虑因素
Emma C Palmer,Michael D Shuman,Isabelle G Oiler
Emma C Palmer
Comparison of alpha-2 agonist versus alpha-1 antagonist for post-traumatic stress disorder-associated nightmares in pediatric patients [0.03%]
α-2激动剂与α-1拮抗剂治疗儿童创伤后应激障碍相关噩梦的比较研究
Seher Khalid,Sandra Mitchell,Cheryl Al-Mateen
Seher Khalid
Introduction: Posttraumatic stress disorder (PTSD) in children and adolescents has a high prevalence of accompanying sleep disturbances. Currently, pediatric treatment of PTSD-related nightmares is extrapolated from adult...
Rural ambulatory care pharmacists providing in-clinic and home visit services improve adherence to long-acting injectable antipsychotics [0.03%]
农村门诊药剂师提供诊所内和家庭访问服务可提高长效抗精神病药物的依从性
Heng Helen Chang,Laura Michelle Vaughn,Danica Liu
Heng Helen Chang
Patients with schizophrenia often experience symptoms such as poor insight and disorganized thought, which limit their ability to seek and receive care consistently. In rural settings, systemic factors, including limited resources and trans...
Implementation and evaluation of interprofessional overdose review team recommendations following intentional or accidental overdose events [0.03%]
多专业用药过量审查团队建议的实施与评估
Monica Barrett,Sarah Kemerer,Michelle Colvard
Monica Barrett
Drug overdose death rates in the United States remain high despite efforts to mitigate this risk. Many communities and hospitals across the country have implemented overdose review teams, including local overdose fatality review teams or po...
Med rec double check: Inpatient psychiatry medication errors identified on admission using Medicaid Web portals and electronic pharmaceutical claims data [0.03%]
基于医保网站和电子药品索赔数据的住院精神病药物错误入院筛查研究
Su Su E Oo,Ian R McGrane
Su Su E Oo
Introduction: The role of pharmacists during medication reconciliation (MR) is well established, with a number of reports describing this in the context of psychiatric hospitalizations. However, medication errors (MEs) ar...