Blood Manganese and Risk of Squamous Cell Carcinomas of the Head and Neck [0.03%]
血液中的锰与头颈部鳞状细胞癌的发病风险关系研究
Benjamin Clay,Nasir Bashir,Stephen Burgess et al.
Benjamin Clay et al.
Importance: Squamous cell carcinomas of the oral cavity (OCSCC), oropharynx (OPSCC), hypopharynx (HPSCC), and larynx (LSCC) are the most common forms of head and neck cancer globally. Epidemiological studies have identifi...
Comparison of Diet and Lifestyle Program With 3 Medication Approaches for Laryngopharyngeal Reflux Disease Management [0.03%]
饮食和生活方式方案与三种药物方法对喉反流疾病管理的比较研究
Jerome R Lechien
Jerome R Lechien
Importance: There are no studies comparing the primary therapeutic options for laryngopharyngeal reflux disease (LPRD). Objective: To c...
Tsukasa Higashionna,Tatsuaki Takeda,Mariko Fujii et al.
Tsukasa Higashionna et al.
Importance: Head and neck cancer (HNC) accounts for nearly 1 million new cases and approximately half a million deaths annually worldwide, representing a substantial global health burden. Despite an overall decline in mor...
Steven J Lo,You-Yan Chen,Fu-Chan Wei
Steven J Lo
Importance: Quality of life (QOL) is considered the second most important outcome after survival in cancer care. In head and neck reconstruction, QOL has long been assumed to stabilize at 1 year, an assumption that guides...
Smell and Taste Disturbances Among Glucagon-Like Peptide-1 Receptor Agonist Users [0.03%]
胰高血糖素样肽-1受体激动剂使用者的嗅觉和味觉障碍
Jonathan Zontag,Nir Zontag
Jonathan Zontag
Importance: Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have gained popularity over the last decade for both glycemic control and weight loss. Although various adverse events have been reported among GLP-1 RA us...
Charles A Riley,Edward D McCoul
Charles A Riley
Artificial Intelligence-Based Risk Prediction Models for Complications After Tongue Cancer Surgery [0.03%]
基于人工智能的舌癌手术后并发症风险预测模型
Dany Y Matar,Anthony Y Matar,Anahita Nimbalkar et al.
Dany Y Matar et al.
Importance: Glossectomy and reconstruction for tongue tumors carries substantial risk of postoperative morbidity, yet current tools offer limited individualized risk stratification. ...
Endoscopic Sinus Surgery for Recurrent Acute Rhinosinusitis: A Randomized Clinical Trial [0.03%]
内窥镜鼻窦手术治疗复发性急性鼻窦炎的随机临床试验
Heidi Kaski,Antti Alakärppä,Aleksi Laajala et al.
Heidi Kaski et al.
Importance: Recurrent acute rhinosinusitis (RARS) decreases quality of life. The effects of endoscopic sinus surgery (ESS) in RARS are understudied. Objec...
Pembrolizumab Plus Quad-Shot Radiotherapy for Recurrent, Unresectable, or Metastatic Head and Neck Cancer: A Nonrandomized Clinical Trial [0.03%]
派姆单抗联合放射治疗复发、不可切除或转移性头颈癌的临床试验
Ryan T Hughes,Sydney Smith,Thomas W Lycan Jr et al.
Ryan T Hughes et al.
Importance: Immune checkpoint inhibitor (ICI) monotherapy for patients with recurrent, unresectable, or metastatic (RUM) head and neck squamous cell carcinoma (HNSCC) is associated with poor outcomes. Low-dose, hypofracti...
Guanru Wang,Jinfeng Liao,Chunjie Li
Guanru Wang