Association of Metformin With the Development of Age-Related Macular Degeneration [0.03%]
二甲双胍与年龄相关性黄斑变性的发生发展之间的关联研究
Amitha Domalpally,Samuel A Whittier,Qing Pan et al.
Amitha Domalpally et al.
Importance: Age-related macular degeneration (AMD) is a leading cause of blindness with no treatment available for early stages. Retrospective studies have shown an association between metformin and reduced risk of AMD. ...
Choosing Analysis Methods to Match Estimands When Investigating Interventions for Macular Disease [0.03%]
在研究黄斑疾病干预措施时选择与目标估计量相匹配的分析方法
Myra B McGuinness,Carla J Abbott
Myra B McGuinness
Antidrug Antibodies to Tumor Necrosis Factor α Inhibitors in Patients With Noninfectious Uveitis [0.03%]
非感染性葡萄膜炎患者肿瘤坏死因子α抑制剂的抗药物抗体
Sunil Bellur,Matthew McHarg,Wijak Kongwattananon et al.
Sunil Bellur et al.
Importance: Tumor necrosis factor inhibitors (TNFis) can induce antidrug antibody (ADA) formation and loss of therapeutic response. However, the utility of ADA testing and the association between ADAs and treatment respon...
Alexandra R Zaloga,Kevin R Card,Carol L Shields
Alexandra R Zaloga
Association of Dietary Nitrate and a Mediterranean Diet With Age-Related Macular Degeneration Among US Adults: The Age-Related Eye Disease Study (AREDS) and AREDS2 [0.03%]
膳食硝酸盐和地中海饮食与美国成年人年龄相关性黄斑变性的关系:年龄相关性眼病研究(AREDS)和AREDS2
Geoffrey K Broadhead,Elvira Agrón,David Peprah et al.
Geoffrey K Broadhead et al.
Importance: Low dietary nitrate intake has previously been suggested to be a risk factor for age-related macular degeneration (AMD) progression; however, this finding has not been replicated in other cohorts or adjusted f...
Variability of High-risk Uveal Melanoma Survival Estimates Across Studies Based on 15-Gene Expression Profiling-In Reply [0.03%]
基于15基因表达谱的高危脉络膜黑色素瘤生存率估计在各研究中的变异性——回复
Arun D Singh,Elaine M Binkley,James F Bena
Arun D Singh
Biosimilar Ranibizumab and Innovator Ranibizumab-Immunogenicity Assessment and Its Impact on Safety and Efficacy [0.03%]
生物类似药ranibizumab与原创ranibizumab的免疫原性评估及其对安全性和有效性的影响力
Ashish Sharma,Nilesh Kumar,Baruch D Kuppermann
Ashish Sharma
Immunogenicity With Ranibizumab Biosimilar SB11 (Byooviz) and Reference Product Lucentis and Association With Efficacy, Safety, and Pharmacokinetics: A Post Hoc Analysis of a Phase 3 Randomized Clinical Trial [0.03%]
雷珠单抗生物类似药SB11(Byooviz)与原研产品卢centis的免疫原性与有效性、安全性和药代动力学的相关性的三期随机临床试验的回顾性分析
Neil M Bressler,Taehyung Kim,Inkyung Oh et al.
Neil M Bressler et al.
Importance: SB11 and reference ranibizumab (RBZ) are monoclonal anti-vascular endothelial growth factor (VEGF)-A antibodies approved for the treatment of neovascular age-related macular degeneration (nAMD) and other retin...
Tyler M Kaplan,Diva R Salomao,Lauren A Dalvin
Tyler M Kaplan
Padmamalini Mahendradas,Harshita Nahata,Isha Acharya
Padmamalini Mahendradas