Long-Term Outcomes and Recovery Trajectories in Out-of-Hospital Cardiac Arrest: A 2-Year Follow-Up of the Randomized Clinical TTM2 Trial [0.03%]
TTM2随机对照试验的2年随访结果及出院后心脏骤停患者的长期预后和康复情况
Malin Hultgren,Erik Blennow Nordström,Susann Ullén et al.
Malin Hultgren et al.
Importance: Guidelines for temperature control following out-of-hospital cardiac arrest (OHCA) are based on trials with end points of 180 days or fewer. O...
Association Between GLP-1 RAs and Idiopathic Intracranial Hypertension [0.03%]
GLP-1受体激动剂与特发性颅内高压之间的关联
Luis Manzano-Hernández,M Millán Vázquez,David León-Jiménez
Luis Manzano-Hernández
Sex Differences in P-Tau217, Tau Aggregation, and Cognitive Decline [0.03%]
性别差异对P-tau217、tau蛋白聚集和认知衰退的影响
Gillian T Coughlan,Valentin Ourry,Diana Townsend et al.
Gillian T Coughlan et al.
Importance: Among individuals with high levels of amyloid-β (Aβ), women exhibit higher insoluble tau burden and accumulation than age-matched men. It remains unclear whether this sex difference is influenced by soluble ...
Error in Editorial [0.03%]
编辑错误
Published Erratum
JAMA neurology. 2026 Feb 1;83(2):200. DOI:10.1001/jamaneurol.2026.0017 2026
James P Ho,David Y Hwang,Amy Brodtmann
James P Ho
Published Erratum
JAMA neurology. 2026 Feb 9:e260046. DOI:10.1001/jamaneurol.2026.0046 2026
Comparative Effectiveness of Brivaracetam, Cenobamate, Lacosamide, and Perampanel in Focal Epilepsy [0.03%]
Brivaracetam、Cenobamate、Lacosamide和Perampanel治疗局灶性癫痫的疗效比较
Emanuele Cerulli Irelli,Roberta Roberti,Maria Sole Borioni et al.
Emanuele Cerulli Irelli et al.
Importance: Treatment decisions in drug-resistant focal epilepsy remain largely empirical, as direct comparative evidence among newer antiseizure medications (ASMs) is limited. Real-world data can complement randomized cl...
Glucocorticoids for Preventing Migraine Recurrence in the Emergency Department [0.03%]
糖皮质激素用于急诊科预防偏头痛的复发
Amy A Gelfand,Serena L Orr,Daniel J Shapiro
Amy A Gelfand
Timothy M Miller,Merit E Cudkowicz,Pamela J Shaw et al.
Timothy M Miller et al.
Importance: Approximately 2% of amyotrophic lateral sclerosis (ALS) cases are attributable to a pathogenic variant in the superoxide dismutase 1 (SOD1) gene. Tofersen, an intrathecal antisense oligonucleotide designed to ...
Clinical Trial
JAMA neurology. 2026 Feb 1;83(2):115-125. DOI:10.1001/jamaneurol.2025.4946 2026
Targeted Remediation of the Ipsilesional Arm in Chronic Stroke: A Randomized Clinical Trial [0.03%]
慢性卒中患者优势半球病变侧上肢的功能 remediation 随机临床试验
Candice Maenza,Carolee J Winstein,Terrence E Murphy et al.
Candice Maenza et al.
Importance: Ipsilesional upper-limb motor deficits after stroke are functionally important yet largely neglected in rehabilitation. Remediation may improve motor outcomes in individuals with severe contralesional arm hemi...