Novel Antimurine Thyroid-Stimulating Hormone Receptor Monoclonal Antibodies [0.03%]
新型抗小鼠甲状腺刺激激素受体单克隆抗体
Alyssa N Klee,James A Torchia,Gordon J Freeman
Alyssa N Klee
Autoantibodies against thyroid proteins are present in several thyroid diseases. Thyroid-stimulating hormone receptor (TSHR) is a G-protein-coupled receptor (GPCR) that binds to thyroid-stimulating hormone (TSH) and stimulates production of...
Efficacy of Burosumab Every 2 Weeks in an Adult with X-Linked Hypophosphatemia: Should We Learn from Children? [0.03%]
X连锁低磷血症成人患者的布罗舒马每周两次给药疗效：能否借鉴儿科患者的经验？
Alessia Marcellino,Silvia Bloise,Carmelo Pirone et al.
Alessia Marcellino et al.
X-linked hypophosphatemia is a genetic condition that leads to fibroblast-growth-factor 23 (FGF23) increase, causing phosphate renal wasting. Since 2018, burosumab, an anti-FGF23 antibody, has been used for this disease with different dosag...
Efficacy and Safety of Anti-SARS-CoV-2 Monoclonal Antibodies: An Updated Review [0.03%]
抗SARS-CoV-2单克隆抗体的疗效和安全性：最新综述
Gandham Ravi,Madhavi Eerike,Venugopala Rao Konda et al.
Gandham Ravi et al.
Monoclonal antibodies (mAbs) had received emergency use authorization for mild-to-moderate coronavirus disease 2019 (COVID-19) or for prophylaxis against COVID-19, including casirivimab plus imdevimab (C+I), bamlanivimab plus etesevimab (B+...
Epitope Mapping of the Novel Anti-Human CCR9 Monoclonal Antibody (C9Mab-11) by 2 × Alanine Scanning [0.03%]
通过两次丙氨酸扫描绘制新型抗人CCR9单克隆抗体(C9Mab-11)的表位图
Yu Isoda,Tomohiro Tanaka,Hiroyuki Suzuki et al.
Yu Isoda et al.
We recently developed a novel anti-human C-C chemokine receptor 9 (hCCR9) monoclonal antibody (mAb), C9Mab-11, which is applicable to flow cytometry, western blotting, and enzyme-linked immunosorbent assay (ELISA). This study aims to identi...
Generation of Rat Monoclonal Antibodies Against Human Epidermal Growth Factor Receptor 2 [0.03%]
抗人表皮生长因子受体2的 rat 单克隆抗体的生成
Honoka Yamamoto,Takeshi Nakanishi,Kan-Ichiro Ihara et al.
Honoka Yamamoto et al.
Human epidermal growth factor receptor 2 (HER2) is a transmembrane tyrosine kinase receptor without any known ligands and a member of the epidermal growth factor receptor (EGFR) family. It is a proto-oncogenic protein that, through signalin...
Epitope Mapping of Anti-Mouse CCR3 Monoclonal Antibodies (C3Mab-6 and C3Mab-7) [0.03%]
抗鼠CCR3单克隆抗体(C3Mab-6和C3Mab-7)的表位鉴定
Nami Tateyama,Teizo Asano,Tomohiro Tanaka et al.
Nami Tateyama et al.
One of G protein-coupled receptors, CC chemokine receptor 3 (CCR3), is expressed in eosinophils, basophils, a subset of Th2 lymphocytes, mast cells, and airway epithelial cells. CCR3 levels in the serum of colorectal cancer patients are sig...
Therapeutic Effects of an Anti-Sialyl Lewis x Antibody in a Murine Model of Acute Lung Injury [0.03%]
抗唾液酸Lewis x抗体在急性肺损伤小鼠模型中的治疗作用
Wenxin Liu,Wei Xiong,Wei Liu et al.
Wenxin Liu et al.
Acute respiratory distress syndrome is a life-threatening acute lung injury (ALI) characterized by the destruction of alveoli leading to pulmonary edema. The infiltration and activation of inflammatory cells and production of inflammatory c...
Production and Characterization of Monoclonal Antibodies Against Structural Proteins of Hirame Novirhabdovirus [0.03%]
鲤春病毒血症病毒结构蛋白单克隆抗体的制备及鉴定
Shyam Kokkattunivarthil Uthaman,Min-Seok Jang,Kyoung-Hui Kong et al.
Shyam Kokkattunivarthil Uthaman et al.
Hirame novirhabdovirus (HIRRV) is a significant viral pathogen of Japanese flounder (Paralichthys olivaceus). In this study, seven monoclonal antibodies (mAbs) against HIRRV (isolate CA-9703) were produced and characterized. Three mAbs (1B3...
Epitope Mapping of an Anti-EpCAM Monoclonal Antibody (EpMab-37) Using the Alanine Scanning Method [0.03%]
采用丙氨酸扫描法测定抗EpCAM单克隆抗体（EpMab-37）的表位定位研究
Guanjie Li,Hiroyuki Suzuki,Tomohiro Tanaka et al.
Guanjie Li et al.
The epithelial cell adhesion molecule (EpCAM) is a type I transmembrane glycoprotein, and plays critical roles in cell adhesion, proliferation, and tumorigenesis. EpCAM has been considered as a promising target for tumor diagnosis and thera...