Development of Direct LDL Measurement by LDL Precipitation Combined with Sandwich ELISA Using In-House-Generated mAbs [0.03%]
基于自制单克隆抗体的LDL沉淀联合夹心ELISA直接测定LDL的方法学研究
Kanokwan Lowhalidanon,Panida Khunkaewla
Kanokwan Lowhalidanon
One of the major risk factors for the progression of cardiovascular diseases is a high blood level of low-density lipoprotein (LDL), so progression of the disease may be prevented by lowering the plasma LDL. Evaluation and monitoring of LDL...
Establishment of a Novel Anti-Human CCR6 Monoclonal Antibody C6Mab-19 with the High Binding Affinity in Flow Cytometry [0.03%]
一种新型高亲和力人CCR6单克隆抗体C6Mab-19的建立及鉴定
Tomohiro Tanaka,Kaishi Kitamura,Hiroyuki Suzuki et al.
Tomohiro Tanaka et al.
CC chemokine receptor 6 (CCR6) is a member of the G-protein-coupled receptor family that is highly expressed in B lymphocytes, effector and memory T cells, regulatory T cells, and immature dendritic cells. CCR6 has been revealed to have imp...
Novel Antimurine Thyroid-Stimulating Hormone Receptor Monoclonal Antibodies [0.03%]
新型抗小鼠甲状腺刺激激素受体单克隆抗体
Alyssa N Klee,James A Torchia,Gordon J Freeman
Alyssa N Klee
Autoantibodies against thyroid proteins are present in several thyroid diseases. Thyroid-stimulating hormone receptor (TSHR) is a G-protein-coupled receptor (GPCR) that binds to thyroid-stimulating hormone (TSH) and stimulates production of...
Efficacy of Burosumab Every 2 Weeks in an Adult with X-Linked Hypophosphatemia: Should We Learn from Children? [0.03%]
X连锁低磷血症成人患者的布罗舒马每周两次给药疗效：能否借鉴儿科患者的经验？
Alessia Marcellino,Silvia Bloise,Carmelo Pirone et al.
Alessia Marcellino et al.
X-linked hypophosphatemia is a genetic condition that leads to fibroblast-growth-factor 23 (FGF23) increase, causing phosphate renal wasting. Since 2018, burosumab, an anti-FGF23 antibody, has been used for this disease with different dosag...
Efficacy and Safety of Anti-SARS-CoV-2 Monoclonal Antibodies: An Updated Review [0.03%]
抗SARS-CoV-2单克隆抗体的疗效和安全性：最新综述
Gandham Ravi,Madhavi Eerike,Venugopala Rao Konda et al.
Gandham Ravi et al.
Monoclonal antibodies (mAbs) had received emergency use authorization for mild-to-moderate coronavirus disease 2019 (COVID-19) or for prophylaxis against COVID-19, including casirivimab plus imdevimab (C+I), bamlanivimab plus etesevimab (B+...
Epitope Mapping of the Novel Anti-Human CCR9 Monoclonal Antibody (C9Mab-11) by 2 × Alanine Scanning [0.03%]
通过两次丙氨酸扫描绘制新型抗人CCR9单克隆抗体(C9Mab-11)的表位图
Yu Isoda,Tomohiro Tanaka,Hiroyuki Suzuki et al.
Yu Isoda et al.
We recently developed a novel anti-human C-C chemokine receptor 9 (hCCR9) monoclonal antibody (mAb), C9Mab-11, which is applicable to flow cytometry, western blotting, and enzyme-linked immunosorbent assay (ELISA). This study aims to identi...
Generation of Rat Monoclonal Antibodies Against Human Epidermal Growth Factor Receptor 2 [0.03%]
抗人表皮生长因子受体2的 rat 单克隆抗体的生成
Honoka Yamamoto,Takeshi Nakanishi,Kan-Ichiro Ihara et al.
Honoka Yamamoto et al.
Human epidermal growth factor receptor 2 (HER2) is a transmembrane tyrosine kinase receptor without any known ligands and a member of the epidermal growth factor receptor (EGFR) family. It is a proto-oncogenic protein that, through signalin...
Epitope Mapping of Anti-Mouse CCR3 Monoclonal Antibodies (C3Mab-6 and C3Mab-7) [0.03%]
抗鼠CCR3单克隆抗体(C3Mab-6和C3Mab-7)的表位鉴定
Nami Tateyama,Teizo Asano,Tomohiro Tanaka et al.
Nami Tateyama et al.
One of G protein-coupled receptors, CC chemokine receptor 3 (CCR3), is expressed in eosinophils, basophils, a subset of Th2 lymphocytes, mast cells, and airway epithelial cells. CCR3 levels in the serum of colorectal cancer patients are sig...
Therapeutic Effects of an Anti-Sialyl Lewis x Antibody in a Murine Model of Acute Lung Injury [0.03%]
抗唾液酸Lewis x抗体在急性肺损伤小鼠模型中的治疗作用
Wenxin Liu,Wei Xiong,Wei Liu et al.
Wenxin Liu et al.
Acute respiratory distress syndrome is a life-threatening acute lung injury (ALI) characterized by the destruction of alveoli leading to pulmonary edema. The infiltration and activation of inflammatory cells and production of inflammatory c...