Development of Monoclonal Antibodies Specific to Either CD300AR111 or CD300AQ111 or Both [0.03%]
特异性针对CD300AR111或CD300AQ111或者同时针对两者之单克隆抗体的开发
Hitoshi Koizumi,Chigusa Nakahashi-Oda,Wenxin Lyu et al.
Hitoshi Koizumi et al.
CD300A is a member of the CD300 immunoglobulin (Ig)-like receptor family consisting of eight molecules in humans, all of which contain one Ig-like domain in the extracellular portion. Upon binding its ligand phosphatidylserine or phosphatid...
Thomas Kieber-Emmons
Thomas Kieber-Emmons
Takashi Tanikawa,James Yu,Kate Hsu et al.
Takashi Tanikawa et al.
Nattokinase is a protease produced by Bacillus subtilis var. natto that exhibits various beneficial biological effects. Thus, a reliable assay to determine nattokinase levels is needed. In this study, we developed novel mouse monoclonal ant...
MAb Targeting a Link Between ExoN and MTase of TGEV NSP14 [0.03%]
针对TGEV NSP14的Exon和MTase之间链接区的单克隆抗体
Lilan Xie,Fang Lin,Peiling Dong et al.
Lilan Xie et al.
Porcine transmissible gastroenteritis virus (TGEV) infection results in severe gastrointestinal disease manifesting vomiting, diarrhea in neonatal porcine, with extremely high mortality. Monoclonal antibody (MAb) specific to TGEV nonstructu...
Development of an Anti-EphB4 Monoclonal Antibody for Multiple Applications Against Breast Cancers [0.03%]
一种用于乳腺癌多种治疗的抗EphB4单克隆抗体的研发
Ren Nanamiya,Hiroyuki Suzuki,Mika K Kaneko et al.
Ren Nanamiya et al.
The erythropoietin-producing hepatocellular carcinoma (Eph) receptors are the largest receptor tyrosine kinase family. EphB4 is essential for cell adhesion and motility during embryogenesis. Pathologically, EphB4 is overexpressed and contri...
Development of an Expression Vector Engineering Strategy Based on tDNA Insulator Element for the Stable Expression of Vascular Endothelial Growth Factor Receptor-Fc Fusion Protein [0.03%]
基于tDNA绝缘子元件的血管内皮生长因子受体融合蛋白稳定表达工程载体构建策略研究
Azam Rahimpour,Meysam Mosallaei,Farzad Pourghazi et al.
Azam Rahimpour et al.
During the past decades, tremendous advances have occurred in manufacturing recombinant therapeutic proteins in Chinese hamster ovary (CHO) cells. Nevertheless, the production of stable high-producing cell lines has remained a major obstacl...
Molecular Investigation of the Association Among Common Interleukin-6 Polymorphism and Human Papillomavirus Genotypes with Cervical Cancer Among Iranian Women [0.03%]
伊朗妇女常见白细胞介素-6基因多态性与人类乳头瘤病毒基因型和宫颈癌关联的分子研究
Parisa Pourroostaei Ardakani,Shadi Abkhiz,Kazhaal Sheykhi et al.
Parisa Pourroostaei Ardakani et al.
Cervical cancer is the fourth most commonly identified cancer and the third important reason for cancer-related death among women in less developed nations. Aside from the human papillomavirus (HPV), the host genetic factors, especially som...
Yuki Nishino,Takujiro Homma,Kan-Ichiro Ihara et al.
Yuki Nishino et al.
Nucleolin (NCL) is a multifunctional phosphoprotein that is mainly localized in the nucleolus, but it is also found in the nucleoplasm, cytoplasm, and cell membrane. The principal functions of NCL involve DNA and RNA metabolism, gene transc...
Development of Direct LDL Measurement by LDL Precipitation Combined with Sandwich ELISA Using In-House-Generated mAbs [0.03%]
基于自制单克隆抗体的LDL沉淀联合夹心ELISA直接测定LDL的方法学研究
Kanokwan Lowhalidanon,Panida Khunkaewla
Kanokwan Lowhalidanon
One of the major risk factors for the progression of cardiovascular diseases is a high blood level of low-density lipoprotein (LDL), so progression of the disease may be prevented by lowering the plasma LDL. Evaluation and monitoring of LDL...
Establishment of a Novel Anti-Human CCR6 Monoclonal Antibody C6Mab-19 with the High Binding Affinity in Flow Cytometry [0.03%]
一种新型高亲和力人CCR6单克隆抗体C6Mab-19的建立及鉴定
Tomohiro Tanaka,Kaishi Kitamura,Hiroyuki Suzuki et al.
Tomohiro Tanaka et al.
CC chemokine receptor 6 (CCR6) is a member of the G-protein-coupled receptor family that is highly expressed in B lymphocytes, effector and memory T cells, regulatory T cells, and immature dendritic cells. CCR6 has been revealed to have imp...