Immune-tolerizing procedure for preparation of monoclonal antibodies against glycoprotein E of Pseudorabies virus [0.03%]
用于伪狂犬病毒糖蛋白E单克隆抗体免耐受的免疫方法
Shun Lu,Min Xiang,Hanbing Dan et al.
Shun Lu et al.
The glycoprotein E (gE) of pseudorabies virus (PRV) is known to be an important marker protein in the control and eradication of Aujeszky's disease. In this study, BALB/c mice were immunized with gE-deleted PRV as tolerogen and with wild-ty...
An anti-human CD13 monoclonal antibody that suppresses the suppressive function of Treg cells [0.03%]
一种针对CD13的抗人单克隆抗体，可抑制Treg细胞的抑制功能
Kai Zhang,Wei Chen,Yun Zhang et al.
Kai Zhang et al.
CD13 (CD13/aminopeptidase N, APN, or CD13/APN) is a widely expressed type II membrane-bound metalloprotease. It is often overexpressed on cancer cells and expressed on CD4(+)CD25(hi) Treg cell subpopulation with higher suppressive ability. ...
Development and characterization of six monoclonal antibodies to hemagglutinin-70 of Clostridium botulinum and their application in a sandwich ELISA [0.03%]
六种针对肉毒杆菌血凝素70的单克隆抗体的发展、表征及其在夹心酶联免疫吸附测定法中的应用
Miles C Scotcher,Luisa W Cheng,Kathryn Ching et al.
Miles C Scotcher et al.
Botulinum neurotoxins (BoNT) are produced by Clostridium botulinum and cause severe neuroparalytic disease that if not treated quickly is often fatal. The toxin is produced as a 150 kDa precursor protein (holotoxin) that is enzymatically cl...
Akashi Ohtaki,Thomas Kieber-Emmons,Ramachandran Murali
Akashi Ohtaki
Two major obstacles in developing cancer vaccines are identifying unique tumor-associated antigens (TAA) and overcoming the lack of structural information about TAAs. Unlike progress with T cell-based vaccines, B cell vaccines are less well...