Prevention of Collagen-Induced Arthritis by an Anti-Glycan Monoclonal Antibody Reactive with 6-Sulfo Sialyl Lewis x in DBA/1 Mice [0.03%]
用抗糖型单克隆抗体预防DBA/1小鼠胶原诱导的关节炎研究
Zihong Wei,Hiroto Kawashima
Zihong Wei
Rheumatoid arthritis (RA) is an autoimmune disease characterized by synovial tissue inflammation, substantially impacting the quality of life of patients. The interaction between L-selectin and its glycoprotein ligands modified with 6-sulfo...
Development and Characterization of a Novel Neuropilin-2 Antibody for Immunohistochemical Staining of Cancer and Sarcoidosis Tissue Samples [0.03%]
一种新颖的神经纤毛蛋白-2抗体的开发及其对癌症和肉芽肿病组织样本免疫组化染色的研究
Sarah Förster,Yeeting E Chong,David Siefker et al.
Sarah Förster et al.
Neuropilin-2 (NRP2) is a cell surface receptor that plays key roles in lymphangiogenesis, but also in pathophysiological conditions such as cancer and inflammation. NRP2 targeting by efzofitimod, a novel immunomodulatory molecule, is curren...
Development of Monoclonal Antibodies Specific to Either CD300AR111 or CD300AQ111 or Both [0.03%]
特异性针对CD300AR111或CD300AQ111或者同时针对两者之单克隆抗体的开发
Hitoshi Koizumi,Chigusa Nakahashi-Oda,Wenxin Lyu et al.
Hitoshi Koizumi et al.
CD300A is a member of the CD300 immunoglobulin (Ig)-like receptor family consisting of eight molecules in humans, all of which contain one Ig-like domain in the extracellular portion. Upon binding its ligand phosphatidylserine or phosphatid...
Thomas Kieber-Emmons
Thomas Kieber-Emmons
Takashi Tanikawa,James Yu,Kate Hsu et al.
Takashi Tanikawa et al.
Nattokinase is a protease produced by Bacillus subtilis var. natto that exhibits various beneficial biological effects. Thus, a reliable assay to determine nattokinase levels is needed. In this study, we developed novel mouse monoclonal ant...
MAb Targeting a Link Between ExoN and MTase of TGEV NSP14 [0.03%]
针对TGEV NSP14的Exon和MTase之间链接区的单克隆抗体
Lilan Xie,Fang Lin,Peiling Dong et al.
Lilan Xie et al.
Porcine transmissible gastroenteritis virus (TGEV) infection results in severe gastrointestinal disease manifesting vomiting, diarrhea in neonatal porcine, with extremely high mortality. Monoclonal antibody (MAb) specific to TGEV nonstructu...
Development of an Anti-EphB4 Monoclonal Antibody for Multiple Applications Against Breast Cancers [0.03%]
一种用于乳腺癌多种治疗的抗EphB4单克隆抗体的研发
Ren Nanamiya,Hiroyuki Suzuki,Mika K Kaneko et al.
Ren Nanamiya et al.
The erythropoietin-producing hepatocellular carcinoma (Eph) receptors are the largest receptor tyrosine kinase family. EphB4 is essential for cell adhesion and motility during embryogenesis. Pathologically, EphB4 is overexpressed and contri...
Development of an Expression Vector Engineering Strategy Based on tDNA Insulator Element for the Stable Expression of Vascular Endothelial Growth Factor Receptor-Fc Fusion Protein [0.03%]
基于tDNA绝缘子元件的血管内皮生长因子受体融合蛋白稳定表达工程载体构建策略研究
Azam Rahimpour,Meysam Mosallaei,Farzad Pourghazi et al.
Azam Rahimpour et al.
During the past decades, tremendous advances have occurred in manufacturing recombinant therapeutic proteins in Chinese hamster ovary (CHO) cells. Nevertheless, the production of stable high-producing cell lines has remained a major obstacl...
Molecular Investigation of the Association Among Common Interleukin-6 Polymorphism and Human Papillomavirus Genotypes with Cervical Cancer Among Iranian Women [0.03%]
伊朗妇女常见白细胞介素-6基因多态性与人类乳头瘤病毒基因型和宫颈癌关联的分子研究
Parisa Pourroostaei Ardakani,Shadi Abkhiz,Kazhaal Sheykhi et al.
Parisa Pourroostaei Ardakani et al.
Cervical cancer is the fourth most commonly identified cancer and the third important reason for cancer-related death among women in less developed nations. Aside from the human papillomavirus (HPV), the host genetic factors, especially som...
Yuki Nishino,Takujiro Homma,Kan-Ichiro Ihara et al.
Yuki Nishino et al.
Nucleolin (NCL) is a multifunctional phosphoprotein that is mainly localized in the nucleolus, but it is also found in the nucleoplasm, cytoplasm, and cell membrane. The principal functions of NCL involve DNA and RNA metabolism, gene transc...