PMab-314: An Anti-Giant Panda Podoplanin Monoclonal Antibody [0.03%]
抗大熊猫单克隆抗体PMab-314:一种抗大熊猫Podoplanin的单克隆抗体
Tsunenori Ouchida,Guanjie Li,Hiroyuki Suzuki et al.
Tsunenori Ouchida et al.
The giant panda (Ailuropoda melanoleuca) is one of the important species in worldwide animal conservation. Because it is essential to understand the disease of giant panda for conservation, histopathological analyses of tissues are importan...
The Gift That Keeps on Giving [0.03%]
源源不断的礼物
Thomas Kieber-Emmons
Thomas Kieber-Emmons
Cx1Mab-1: A Novel Anti-mouse CXCR1 Monoclonal Antibody for Flow Cytometry [0.03%]
新型抗鼠CXCR1单克隆抗体Cx1Mab-1及功能研究
Guanjie Li,Tomohiro Tanaka,Tsunenori Ouchida et al.
Guanjie Li et al.
The C-X-C motif chemokine receptor-1 (CXCR1) is a rhodopsin-like G-protein-coupled receptor, expressed on the cell surface of immune cells and tumors. CXCR1 interacts with some C-X-C chemokines, such as CXCL6, CXCL7, and CXCL8/interleukin-8...
Establishment of a Novel Cancer-Specific Anti-HER2 Monoclonal Antibody H2Mab-250/H2CasMab-2 for Breast Cancers [0.03%]
用于治疗乳腺癌的新一代肿瘤特异性抗HER2单克隆抗体H2Mab-250/H2CasMab-2的研制
Mika K Kaneko,Hiroyuki Suzuki,Yukinari Kato
Mika K Kaneko
Overexpression of human epidermal growth factor receptor 2 (HER2) in breast and gastric cancers is an important target for monoclonal antibody (mAb) therapy. All therapeutic mAbs, including anti-HER2 mAbs, exhibit adverse effects probably d...
Monoclonal Antibody Rat 2F11 and Rabbit A3 Against Anti-H2b3b [0.03%]
抗H-2b3b的单克隆抗体rat 2F11和rabbit A3
Saki Egashira,Taro Tachibana,Mako Nakamura et al.
Saki Egashira et al.
Establishment of a Novel Anti-Mouse CCR1 Monoclonal Antibody C1Mab-6 [0.03%]
新型抗鼠CCR1单克隆抗体C1Mab-6的建立
Tsunenori Ouchida,Yu Isoda,Takuro Nakamura et al.
Tsunenori Ouchida et al.
C-C motif chemokine receptor 1 (CCR1/CD191) is a member of G-protein-coupled receptors and is expressed on myeloid cells, such as neutrophils and macrophages. Because the CCR1 signaling promotes tumor expansion in the tumor microenvironment...
Epitope Mapping of an Anti-Mouse CD39 Monoclonal Antibody Using PA Scanning and RIEDL Scanning [0.03%]
使用PA扫描和RIEDL扫描法绘制抗鼠CD39单克隆抗体的表位图谱
Yuki Okada,Hiroyuki Suzuki,Tomohiro Tanaka et al.
Yuki Okada et al.
A cell-surface ectonucleotidase CD39 mediates the conversion of extracellular adenosine triphosphate into immunosuppressive adenosine with another ectonucleotidase CD73. The elevated adenosine in the tumor microenvironment attenuates antitu...
Cx3Mab-4: A Novel Anti-Mouse CXCR3 Monoclonal Antibody for Flow Cytometry [0.03%]
新型抗小鼠CXCR3单克隆抗体Cx3Mab-4
Tsunenori Ouchida,Yu Isoda,Tomohiro Tanaka et al.
Tsunenori Ouchida et al.
C-X-C motif chemokine receptor 3 (CXCR3, CD183) is a G-protein-coupled receptor for CXCL9, CXCL10, and CXCL11. CXCR3 induces chemotaxis of immune cells and promotes inflammation. Various mouse models have been developed to mimic the pathoge...
Epitope Mapping of an Anti-CD44v4 Monoclonal Antibody (C44Mab-108) Using Enzyme-Linked Immunosorbent Assay [0.03%]
基于酶联免疫吸附实验的抗CD44v4单克隆抗体(C44Mab-108)表位鉴定
Hiroyuki Suzuki,Mayuki Tawara,Aoi Hirayama et al.
Hiroyuki Suzuki et al.
CD44 is a type I transmembrane glycoprotein and possesses various isoforms which are largely classified into CD44 standard (CD44s) and CD44 variant (CD44v) isoforms. Some variant-encoded regions play critical roles in tumor progression. How...
Saki Egashira,Taro Tachibana,Mako Nakamura et al.
Saki Egashira et al.
H2b3b is one of the histone H2b isoforms that differs from canonical H2b by five to six amino acids. Previously, we identified H3t as the testis-specific histone H3 variant located in histone cluster 3, which is also the site of H2b3b. In t...