Two Monoclonal Antibodies Targeting Distinct Subdomains of Human Norovirus P Protein [0.03%]
两种针对人诺如病毒P蛋白不同亚区的单克隆抗体
Nianzhu Jiang,Xin He,Yaoming Li
Nianzhu Jiang
The human norovirus (HuNov) major capsid VP1comprises an S (shell) and a P (protruding) domain; the latter is responsible for virus attachment and infection. The dimeric formation of P (containing P1 and P2 subdomains) is indispensable for ...
Experimental Determination of Antibody Affinity and Avidity: Guidance and Considerations [0.03%]
抗体亲和力及亲合力的实验测定：指导和考量
Andrei Moroz,Cory L Brooks
Andrei Moroz
Development and Epitope Mapping of Seven Mouse Anti-Human Coagulation Factor XIII-B Subunit Monoclonal Antibodies [0.03%]
七种小鼠抗人凝血因子 XIII-B亚单位单克隆抗体的开发及表位鉴定
Tsukasa Osaki,Yasuo Magari,Masayoshi Souri et al.
Tsukasa Osaki et al.
Coagulation factor XIII (FXIII) is an enzyme that strengthens hemostatic clots, and its deficiency can cause life-threatening bleeding. We immunized mice with human plasma-derived FXIII to generate monoclonal antibodies (mAbs) against the B...
Heinz Kohler
Heinz Kohler
This Long-Covid disease, mild or severe, is multiorgan or system-wide, spanning from fatigue to clotting abnormalities and autoantibody. The spectrum of different symptoms in Long-Covid diseases makes it difficult to point to a common immun...
Bailin Tu,Zhihong Lin,Jeff Moore et al.
Bailin Tu et al.
Mammalian cell line stability is an important consideration when establishing a biologics manufacturing process in the biopharmaceutical and in vitro diagnostics (IVD) industries. Traditional Chinese hamster ovary (CHO) cell line developmen...
Development of Sensitive Anti-Mouse CCR5 Monoclonal Antibodies Using the N-Terminal Peptide Immunization [0.03%]
利用N-末端肽免疫开发敏感的抗鼠CCR5单克隆抗体
Rena Ubukata,Hiroyuki Suzuki,Tomohiro Tanaka et al.
Rena Ubukata et al.
One of the G protein-coupled receptors, C-C chemokine receptor 5 (CCR5), is an important regulator for the activation of T and B lymphocytes, dendritic cells, natural killer cells, and macrophages. Upon binding to its ligands, CCR5 activate...
Generation of a Rat Monoclonal Antibody for Human PAICS, a de novo Purine Biosynthetic Enzyme [0.03%]
人PAICS（从头合成嘌呤酶）单克隆抗体大鼠杂交瘤的建立
Chikako Yokoyama,Kaori Bando,Momoka Yamagata et al.
Chikako Yokoyama et al.
Phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS) is a de novo purine biosynthetic enzyme. It has been found to be overexpressed in various types of cancer and is related to cell pr...
Epitope Mapping of an Anti-Mouse CCR8 Monoclonal Antibody C8Mab-2 Using Flow Cytometry [0.03%]
流式细胞术测定小鼠CCR8单抗C8Mab-2表位图谱
Hiyori Kobayashi,Hiroyuki Suzuki,Tomohiro Tanaka et al.
Hiyori Kobayashi et al.
The C-C motif chemokine receptor 8 (CCR8) is highly and selectively expressed in regulatory T (Treg) cells and is associated with tumor progression. The massive accumulation of Treg cells into tumors suppresses the effector function of CD8+...
Development of a Sensitive Anti-Mouse CCR5 Monoclonal Antibody for Flow Cytometry [0.03%]
一种用于流式细胞仪的敏感抗鼠CCR5单克隆抗体的发展
Hiroyuki Suzuki,Tomohiro Tanaka,Guanjie Li et al.
Hiroyuki Suzuki et al.
C-C chemokine receptor 5 (CCR5), a member of the G protein-coupled receptor family, is the most common coreceptor for the human immunodeficiency virus type 1. CCR5 is also involved in the pathogenesis of tumors and inflammatory diseases. Th...
Correction to: Establishment of a Novel Cancer-Specific Anti-HER2 Monoclonal Antibody H2Mab-250/H2CasMab-2 for Breast Cancers'' by Kaneko et al. Monoclonal Antibodies in Immunodiagnosis and Immunotherapy 2024;43(2):35-43; doi: 10.1089/mab.2023.0033 [0.03%]
对канеко等人的“新型癌症特异性抗her2单克隆抗体h2mab-250/h2casmab-2的建立”一文的勘误（乳腺癌）免疫诊断与免疫治疗中的单克隆抗体 2024年第43卷第2期，第35-43页；doi: 10.1089/mab.2023.0033