Immunocytochemical Characterization of Alzheimer's Disease Hallmarks in APP/PS1 Transgenic Mice Treated with a New Anti-Amyloid- β Vaccine [0.03%]
新型抗 amyloid-β 疫苗治疗APP/PS1转基因小鼠模型的免疫细胞化学表征研究
Ivan Carrera,Ignacio Etcheverria,Yi Li et al.
Ivan Carrera et al.
Introduction: APP/PS1 double-transgenic mouse models of Alzheimer's disease (AD), which overexpress mutated forms of the gene for the human amyloid precursor protein (APP) and presenilin 1 (PS1), have provided robust neur...
Genotype frequencies of polymorphic MDR1 variants in the Kazakhstani population [0.03%]
哈萨克斯坦人口中多态性MDR1变异的基因型频率
Samat Kozhakhmetov,Adil Supiyev,Almagul Kushugulova et al.
Samat Kozhakhmetov et al.
Introduction: Statins appear to be handled by an ATP-dependent membrane transporter and three SNPs (C1236T (rs1128503), G2677T (rs2032582), and C3435T (rs1045642), which capture the common genetic variation at this locus....
Saule Saduakhasova,Almagul Kushugulova,Samat Kozhakhmetov et al.
Saule Saduakhasova et al.
Introduction: Available evidence suggests that probiotics have different biological functions that depend on several mechanisms, such as antioxidant and DNA-protective activities. The probiotic consortium includes bacteri...
Saule Saduakhasova,Almagul Kushugulova,Samat Kozhakhmetov et al.
Saule Saduakhasova et al.
Introduction: The immune-modulatory effects of synbiotics and their ability to reduce free radical levels may be useful for functional food that is able to be active throughout whole period of colonization of the gastroin...
Complete Genome Sequence of the Probiotic Lactic Acid Bacterium Lactobacillus Rhamnosus [0.03%]
鼠李糖乳杆菌的完整基因组序列
Samat Kozhakhmetov,Almagul Kushugulova,Adil Supiyev et al.
Samat Kozhakhmetov et al.
Introduction: Lactobacilli are a bacteria commonly found in the gastrointestinal tract. Some species of this genus have probiotic properties. The most common of these is Lactobacillus rhamnosus, a microoganism, generally ...
Effects of Antioxidants and Vitamins on the Proliferation of Human Diploid Cells [0.03%]
抗氧化剂和维生素对人二倍体细胞增殖的影响
Gaziza Dаnlybaeva,Assel Isabekova,Zhansaya Akhmadeyeva
Gaziza Dаnlybaeva
Introduction: Microelements, essential nutrients that are needed in small amounts including minerals such as calcium, zinc, iron and other vitamins (A, B, C, and etc.), are macronutrients necessary for a healthy life.The ...
Randomized Clinical Trial: Efficacy of a New Synbiotic in Adults with Metabolic Syndrome [0.03%]
新型合生元治疗代谢综合征患者的疗效随机临床试验研究
Almagul Kushugulova,Valerii Benberin,Raushan Karabayeva et al.
Almagul Kushugulova et al.
Introduction: Metabolic syndrome is a lifestyle disease and is a frequent problem among the adult population. Human gut microbiota plays a key role in the development of metabolic syndrome. Recently, the gut microbiota ha...
Study of the erythropoiesis activity of nano-encapsulated forms of erythropoietin [0.03%]
纳米包封促红细胞生成素的促红细胞生长研究
Zhanagul Khasenbekova,Alexandr Gulayev,Elena Nechayeva et al.
Zhanagul Khasenbekova et al.
Introduction: The recombinant human erythropoietin (rhEPO) is used in the treatment of anemia. In order to improve its pharmacokinetic properties, nanoparticles of biodegradable polymers of natural or synthetic origin wer...
Effect of Probiotic Consortium on the Local Inflammatory Process in Chronic Periodontitis [0.03%]
益生菌联合制剂对慢性牙周炎局部炎症过程的影响
Zhanagul Khasenbekova,Saule Saduakhasova,Alexandr Gulayev et al.
Zhanagul Khasenbekova et al.
Introduction: Inflammatory periodontal disease is one of the major concerns of researchers and clinicians, because it can lead to tooth loss and an increased risk of systemic pathologies, even at the age of 35. The purpos...
The Central Asian Journal of Global Health to Increase Scientific Productivity [0.03%]
中亚全球卫生杂志增加科研产出
Kyle Freese,Eugene Shubnikov,Ron LaPorte et al.
Kyle Freese et al.
The WHO Collaborating Center at the University of Pittsburgh, USA partnering with Nazarbayev University, developed the Central Asian Journal of Global Health (CAJGH, cajgh.pitt.edu) in order to increase scientific productivity in Kazakhstan...